Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Süleyman, Bozkurt"'
Autor:
Benedikt Sauer, Jan Kueckelhaus, Nadja I. Lorenz, Süleyman Bozkurt, Dorothea Schulte, Jan‐Béla Weinem, Mohaned Benzarti, Johannes Meiser, Hans Urban, Giulia Villa, Patrick N. Harter, Christian Münch, Johannes Rieger, Joachim P. Steinbach, Dieter Henrik Heiland, Michael W. Ronellenfitsch
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)
Abstract Glioblastoma, the most frequent primary malignant brain tumour in adults, is characterised by profound yet dynamic hypoxia and nutrient depletion. To sustain survival and proliferation, tumour cells are compelled to acquire metabolic plastic
Externí odkaz:
https://doaj.org/article/953fce7d5fd0419cb7f6878acc45a495
Autor:
Mahil Lambert, Jakob Gebel, Charlotte Trejtnar, Nicole Wesch, Süleyman Bozkurt, Martin Adrian-Allgood, Frank Löhr, Christian Münch, Volker Dötsch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The p53 family member TAp63α plays an important role in maintaining the genetic integrity in oocytes. DNA damage, in particular DNA double strand breaks, lead to the transformation of the inhibited, only dimeric conformation into the active
Externí odkaz:
https://doaj.org/article/0bcc9b700f734ed4a581d69e6765fd1c
Autor:
Cristian Prieto‐Garcia, Oliver Hartmann, Michaela Reissland, Fabian Braun, Süleyman Bozkurt, Nikolett Pahor, Carmina Fuss, Andreas Schirbel, Christina Schülein‐Völk, Alexander Buchberger, Marco A. Calzado Canale, Mathias Rosenfeldt, Ivan Dikic, Christian Münch, Markus E. Diefenbacher
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3082-3106 (2022)
Oncogenic transformation of lung epithelial cells is a multistep process, frequently starting with the inactivation of tumour suppressors and subsequent development of activating mutations in proto‐oncogenes, such as members of the PI3K or MAPK fam
Externí odkaz:
https://doaj.org/article/dce85c56cd0547f996b0cfb97c5fb3dc
Autor:
Jonas Benjamin Michaelis, Melinda Elaine Brunstein, Süleyman Bozkurt, Ludovico Alves, Martin Wegner, Manuel Kaulich, Christian Pohl, Christian Münch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mitophagy activation is mediated by mitochondrial depolarization. Here, the authors show that mitochondrial protein misfolding can activate mitophagy in a depolarization-independent manner mediated by a protein import reduction.
Externí odkaz:
https://doaj.org/article/28bd4ad93a744efda167cac0232e31a7
Publikováno v:
Bio-Protocol, Vol 12, Iss 24 (2022)
Mitochondria are cellular organelles essential for the function and survival of eukaryotic cells. Nearly all mitochondrial proteins are nuclear-encoded and require mitochondrial import upon their synthesis in the cytosol. Various approaches have been
Externí odkaz:
https://doaj.org/article/7f4c09d093be4471bf3a1d48e7c685ee
Autor:
Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt
Publikováno v:
Cells, Vol 12, Iss 1, p 201 (2023)
Therapy resistance is still a major reason for treatment failure in colorectal cancer (CRC). Previously, we identified the E3 ubiquitin ligase TRIM25 as a novel suppressor of caspase-2 translation which contributes to the apoptosis resistance of CRC
Externí odkaz:
https://doaj.org/article/5ff8f1fb40bd42789addf87a4fcb2828
Autor:
Daniel Schmitt, Süleyman Bozkurt, Pascale Henning-Domres, Heike Huesmann, Stefan Eimer, Laura Bindila, Christian Behrends, Emily Boyle, Florian Wilfling, Georg Tascher, Christian Münch, Christian Behl, Andreas Kern
Publikováno v:
Autophagy
Autophagosome isolation enables the thorough investigation of structural components and engulfed materials. Recently, we introduced a novel antibody-based FACS-mediated method for isolation of native macroautophagic/autophagic vesicles and confirmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f09f2ac023f2feacfd74579c7dda4c2
https://hdl.handle.net/21.11116/0000-000B-7E83-4
https://hdl.handle.net/21.11116/0000-000B-7E83-4
Autor:
Sarah Rehbein, Anna-Lena Possmayer, Süleyman Bozkurt, Catharina Lotsch, Julia Gerstmeier, Michael Burger, Stefan Momma, Claudia Maletzki, Carl-Friedrich Classen, Thomas M. Freiman, Daniel Dubinski, Katrin Lamszus, Bryan W. Day, Brett W. Stringer, Christel Herold-Mende, Christian Münch, Donat Kögel, Benedikt Linder
Glioblastoma is the most common primary brain cancer in adults and represents one of the worst cancer diagnosis for the patients. Suffering from a poor prognosis and limited treatment options, tumor recurrences are virtually inevitable. Additionally,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd118ac43c6b6f1142c1dd4faf132f4
https://doi.org/10.1101/2023.05.16.540926
https://doi.org/10.1101/2023.05.16.540926
Autor:
Eberhardt, Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang
Publikováno v:
Cells; Volume 12; Issue 1; Pages: 201
Therapy resistance is still a major reason for treatment failure in colorectal cancer (CRC). Previously, we identified the E3 ubiquitin ligase TRIM25 as a novel suppressor of caspase-2 translation which contributes to the apoptosis resistance of CRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::1eae38f4b697a1a93ecf752e3aff01c6
Publikováno v:
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity. 26:1357-1363
It is known that childhood maltreatment and problematic eating behaviors are higher in bariatric surgery patients compared to over- and normal-weight persons. The aim of the study is to investigate the relationship between childhood maltreatment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f335f49a773003cb807afbfddb87bc51
https://doi.org/10.1007/s40519-020-00943-2
https://doi.org/10.1007/s40519-020-00943-2