Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Søren Preus"'
Autor:
Anders Foller Füchtbauer, Søren Preus, Karl Börjesson, Scott A. McPhee, David M. J. Lilley, L. Marcus Wilhelmsson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA.
Externí odkaz:
https://doaj.org/article/f9924c7b2eb845ad804425dc82e6bff6
Autor:
Scott A. McPhee, Karl Börjesson, David M.J. Lilley, Anders Foller Füchtbauer, Søren Preus, L. Marcus Wilhelmsson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA. We here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd373b3900f68629e71f878248c4db6c
https://doaj.org/article/f9924c7b2eb845ad804425dc82e6bff6
https://doaj.org/article/f9924c7b2eb845ad804425dc82e6bff6
Publikováno v:
Selnihhin, D, Sparvath, S M, Preus, S, Birkedal, V & Andersen, E S 2018, ' Multifluorophore DNA Origami Beacon as a Biosensing Platform ', ACS Nano, vol. 12, no. 6, pp. 5699–5708 . https://doi.org/10.1021/acsnano.8b01510
Biosensors play increasingly important roles in many fields, from clinical diagnosis to environmental monitoring, and there is a growing need for cheap and simple analytical devices. DNA nanotechnology provides methods for the creation of sophisticat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e593cde97680c8942156cc65c75c70e
https://pure.au.dk/portal/da/publications/multifluorophore-dna-origami-beacon-as-a-biosensing-platform(193f5400-a55d-4e34-9999-19d8e8cb4797).html
https://pure.au.dk/portal/da/publications/multifluorophore-dna-origami-beacon-as-a-biosensing-platform(193f5400-a55d-4e34-9999-19d8e8cb4797).html
Autor:
Søren Preus, Mikayel Aznauryan, Sofie L. Noer, Daniel Gudnason, Jean-Louis Mergny, Victoria Birkedal
Publikováno v:
Kragh, S L, Preus, S, Gudnason, D A, Aznauryan, M, Mergny, J-L & Birkedal, V 2016, ' Folding dynamics and conformational heterogeneity of human telomeric G-quadruplex structures in Na+ solutions by single molecule FRET microscopy ', Nucleic Acids Research, vol. 44, no. 1, pp. 464-471 . https://doi.org/10.1093/nar/gkv1320
Nucleic Acids Research
Nucleic Acids Research
G-quadruplex structures can occur throughout the genome, including at telomeres. They are involved in cellular regulation and are potential drug targets. Human telomeric G-quadruplex structures can fold into a number of different conformations and sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ec2edb09577e24d36d13dc4a11ea14
https://doi.org/10.1093/nar/gkv1320
https://doi.org/10.1093/nar/gkv1320
Autor:
L. Marcus Wilhelmsson, Bo Albinsson, Anke Dierckx, Michael Pittelkow, Thitinun Karpkird, Søren Preus, Søren Jønck
Publikováno v:
Photochemical & Photobiological Sciences. 12:1416-1422
While fluorescent analogues of the canonical nucleobases have proven to be highly valuable in a large number of applications, up until today, fluorescent DNA base analogues remain virtually inapplicable for single-molecule fluorescence experiments wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9289bef9f88e9ba230dcf65f4ac439ff
https://doi.org/10.1039/c3pp50057h
https://doi.org/10.1039/c3pp50057h
Publikováno v:
Preus, S, Hildebrandt, L L & Birkedal, V 2016, ' Optimal Background Estimators in Single-Molecule FRET Microscopy ', Biophysical Journal, vol. 111, no. 6, pp. 1278-1286 . https://doi.org/10.1016/j.bpj.2016.07.047
Single-molecule total internal reflection fluorescence (TIRF) microscopy constitutes an umbrella of powerful tools that facilitate direct observation of the biophysical properties, population heterogeneities, and interactions of single biomolecules w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836382ae9d70d354546955b052ea3c4d
https://europepmc.org/articles/PMC5034361/
https://europepmc.org/articles/PMC5034361/
Publikováno v:
Savic, A G, Preus, S, Rebecchi, L & Guidetti, R 2016, ' New multivariate image analysis method for detection of differences in chemical and structural composition of chitin structures in tardigrade feeding apparatuses ', Zoomorphology, vol. 135, no. 1, pp. 43-50 . https://doi.org/10.1007/s00435-015-0295-2
The feeding apparatus of the eutardigrade Paramacrobiotus richtersi was examined with confocal laser scanning microscopy using three different wavelengths, taking advantage of the autofluorescence of the chitin present in its structures. The main goa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f55c83075f1c878bcb3dcbabc247e58
https://pure.au.dk/portal/da/publications/new-multivariate-image-analysis-method-for-detection-of-differences-in-chemical-and-structural-composition-of-chitin-structures-in-tardigrade-feeding-apparatuses(43267f90-8bf8-4b7f-9ac3-0ffd64e2ef15).html
https://pure.au.dk/portal/da/publications/new-multivariate-image-analysis-method-for-detection-of-differences-in-chemical-and-structural-composition-of-chitin-structures-in-tardigrade-feeding-apparatuses(43267f90-8bf8-4b7f-9ac3-0ffd64e2ef15).html
Publikováno v:
Preus, S, Hildebrandt, L & Birkedal, V 2016, ' Influence of the Background in Single Molecule FRET TIRF Microscopy ', Biophysical Journal, vol. 110, no. 3, supp. 1, 970-Plat, pp. 194a . https://doi.org/10.1016/j.bpj.2015.11.1083
Single-molecule total internal reflection fluorescence (TIRF) microscopy combined with Forster Resonance Energy Transfer (FRET) is a powerful tool that allows direct observation of structural dynamics and heterogeneities without the need for ensemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740e3ab9143c7e5368bf6c6f67163b81
https://pure.au.dk/portal/da/publications/influence-of-the-background-in-single-molecule-fret-tirf-microscopy(d1d7b363-fc01-4218-a705-ea07b57861b3).html
https://pure.au.dk/portal/da/publications/influence-of-the-background-in-single-molecule-fret-tirf-microscopy(d1d7b363-fc01-4218-a705-ea07b57861b3).html
Publikováno v:
Hildebrandt, L, Preus, S & Birkedal, V 2015, ' Quantitative single molecule FRET efficiency using TIRF microscopy ', Faraday Discussions, vol. 184, pp. 131-142 . https://doi.org/10.1039/c5fd00100e
Förster resonance energy transfer (FRET) microscopy at the single molecule level has the potential to yield information on intra and intermolecular distances within the 2–10 nm range of molecules or molecular complexes that undergo frequent confor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2c7fc59a04da6525d12c5477df76c4
https://pure.au.dk/portal/da/publications/quantitative-single-molecule-fret-efficiency-using-tirf-microscopy(d99b4f10-4865-4058-a1ee-b1bde1480ac8).html
https://pure.au.dk/portal/da/publications/quantitative-single-molecule-fret-efficiency-using-tirf-microscopy(d99b4f10-4865-4058-a1ee-b1bde1480ac8).html
Autor:
Christopher P. Lawson, Søren Preus, Marcus Wilhelmsson, Blaise Dumat, Henrik Gradén, Mattias Bood, Anders Foller Larsen, Morten Grøtli, Moa Sandberg Wranne
Publikováno v:
Scientific Reports
Larsen, A F, Dumat, B, Wranne, M S, Lawson, C P, Preus, S, Bood, M, Graden, H, Wilhelmsson, L M & Grøtli, M 2015, ' Development of bright fluorescent quadracyclic adenine analogues : TDDFT-calculation supported rational design ', Scientific Reports, vol. 5, 12653 . https://doi.org/10.1038/srep12653
Larsen, A F, Dumat, B, Wranne, M S, Lawson, C P, Preus, S, Bood, M, Graden, H, Wilhelmsson, L M & Grøtli, M 2015, ' Development of bright fluorescent quadracyclic adenine analogues : TDDFT-calculation supported rational design ', Scientific Reports, vol. 5, 12653 . https://doi.org/10.1038/srep12653
Fluorescent base analogues (FBAs) comprise a family of increasingly important molecules for the investigation of nucleic acid structure and dynamics. We recently reported the quantum chemical calculation supported development of four microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3280bf914a243c3bddebc59a3ed25376
https://doi.org/10.1038/srep12653
https://doi.org/10.1038/srep12653