Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Søren Kofoed, Rasmussen"'
Autor:
Søren Kofoed Rasmussen, Davide Vito, Jens Christian Eriksen, Dietmar Weilguny, C. Mark Smales, Christian Skjødt
Publikováno v:
iScience
iScience, Vol 23, Iss 1, Pp-(2020)
iScience, Vol 23, Iss 1, Pp-(2020)
Summary How the long non-coding RNA (lncRNA) genome in recombinant protein producing Chinese hamster ovary (CHO) cell lines relates to phenotype is not well described. We therefore defined the CHO cell lncRNA transcriptome from cells grown in control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cb2db8b391db39833188dde2b527d3
Autor:
Dietmar Weilguny, Christian Müller, Anne Mathilde Lund, Jette Wagtberg Sen, Cleo Kontoravdi, Søren Kofoed Rasmussen, Yuzhou Fan, Ioscani Jimenez del Val, Michael J. Betenbaugh, Mikael Rørdam Andersen, Deniz Baycin-Hizal
Publikováno v:
Biotechnology and Bioengineering. 112:2172-2184
In this study, omics-based analysis tools were used to explore the effect of glucose starvation and culture duration on monoclonal antibody (mAb) production in fed-batch CHO cell culture to gain better insight into how these parameters can be control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3ff5f631ee5d6f7a7ba698974c7826
https://doi.org/10.1002/bit.25620
https://doi.org/10.1002/bit.25620
Autor:
Ioscani Jimenez del Val, Cleo Kontoravdi, Jette Wagtberg Sen, Søren Kofoed Rasmussen, Yuzhou Fan, Dietmar Weilguny, Christian Müller, Mikael Rørdam Andersen
Publikováno v:
Biotechnology and Bioengineering. 112:521-535
Fed-batch Chinese hamster ovary (CHO) cell culture is the most commonly used process for IgG production in the biopharmaceutical industry. Amino acid and glucose consumption, cell growth, metabolism, antibody titer, and N-glycosylation patterns are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8820f132a264570fd70977e278d3f2db
https://doi.org/10.1002/bit.25450
https://doi.org/10.1002/bit.25450
Autor:
Yuzhou, Fan, Ioscani, Jimenez Del Val, Christian, Müller, Anne Mathilde, Lund, Jette Wagtberg, Sen, Søren Kofoed, Rasmussen, Cleo, Kontoravdi, Deniz, Baycin-Hizal, Michael J, Betenbaugh, Dietmar, Weilguny, Mikael Rørdam, Andersen
Publikováno v:
Biotechnology and bioengineering. 112(10)
In this study, omics-based analysis tools were used to explore the effect of glucose starvation and culture duration on monoclonal antibody (mAb) production in fed-batch CHO cell culture to gain better insight into how these parameters can be control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fe24be0436185bf75fe12fa4ccccf78
https://pubmed.ncbi.nlm.nih.gov/25899530
https://pubmed.ncbi.nlm.nih.gov/25899530
Publikováno v:
Animal Cell Biotechnology: In Biologics Production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88b77825a8a31ceb92b884cbfd74f71
https://doi.org/10.1515/9783110278965.280
https://doi.org/10.1515/9783110278965.280
Autor:
Yuzhou, Fan, Ioscani, Jimenez Del Val, Christian, Müller, Jette, Wagtberg Sen, Søren Kofoed, Rasmussen, Cleo, Kontoravdi, Dietmar, Weilguny, Mikael Rørdam, Andersen
Publikováno v:
Biotechnology and bioengineering. 112(3)
Fed-batch Chinese hamster ovary (CHO) cell culture is the most commonly used process for IgG production in the biopharmaceutical industry. Amino acid and glucose consumption, cell growth, metabolism, antibody titer, and N-glycosylation patterns are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::123025de00c5269ef479cecbd9715a00
https://pubmed.ncbi.nlm.nih.gov/25220616
https://pubmed.ncbi.nlm.nih.gov/25220616
Autor:
Dietmar Weilguny, Torben P. Frandsen, Lars S. Nielsen, Henrik Næsted, Frank Nygaard, Nina T. Mønster, Anne Bondgaard Tolstrup, Søren Kofoed Rasmussen, Christian Müller, Thomas Bouquin
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 5, Iss Suppl 8, p O2 (2011)
BMC Proceedings, Vol 5, Iss Suppl 8, p O2 (2011)
Background Recombinant antibody mixtures represent an important new class of antibody therapeutics as demonstrated by the increasing amount of literature showing that combinations of two or more antibodies show superiority compared to monoclonal anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03fd18d0c2a2dd15d1e39eba7b62a1f
https://pubmed.ncbi.nlm.nih.gov/22373259
https://pubmed.ncbi.nlm.nih.gov/22373259
Autor:
Anne Bondgaard Tolstrup, Søren Kofoed Rasmussen, Henrik Næsted, Christian Müller, Torben P. Frandsen
Publikováno v:
Archives of biochemistry and biophysics. 526(2)
Recombinant monoclonal antibodies have during the last two decades emerged as a very successful class of biological drugs for the treatment of a variety of different diseases used either as biological mono therapy or in combination with small molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9dd77ec3d1ffc5e6eaf6816b4da9a4
https://pubmed.ncbi.nlm.nih.gov/22820097
https://pubmed.ncbi.nlm.nih.gov/22820097
Autor:
Cecilia Förberg, Peter Hauptig, Margareta Wikén, Anne Bondgaard Tolstrup, Søren Kofoed Rasmussen, Henrik Næsted, Yun Jiang, Susan J. Thorpe, Finn C. Wiberg, Lone Kjaer Rasmussen, Anne Marie Valentin Jensen, Anders Engström, Torben P. Frandsen, Pia Persson
Publikováno v:
Biotechnology and bioengineering. 108(9)
The beneficial effect of antibody therapy in human disease has become well established mainly for the treatment of cancer and immunological disorders. The inherent monospecificity of mAbs present limitations to mAb therapy which have become apparent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77feea29697c4bf9c377c14c652de1e
https://pubmed.ncbi.nlm.nih.gov/21495017
https://pubmed.ncbi.nlm.nih.gov/21495017
Autor:
Allan Jensen, Søren Bregenholt, Jackie Duggan, Irene Naylor, Hansen Margit H, Søren Kofoed Rasmussen, Tine Rugh Poulsen, Linda Easterbrook, Lucilla Steinaa, Johan Lantto, Mike Dennis, John Haurum
The eradication of smallpox (variola) and the subsequent cessation of routine vaccination have left modern society vulnerable to bioterrorism employing this devastating contagious disease. The existing, licensed vaccines based on live vaccinia virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f60434bb59e598cdc78933eb053d4d
https://europepmc.org/articles/PMC3028881/
https://europepmc.org/articles/PMC3028881/