Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Søren Kamp"'
1
Hidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume are significantly reduced in uninvolved hair follicles from patients with hidradenitis suppurativa
Autor: Kåre Kemp, Gregor B.E. Jemec, Bente Pakkenberg, Cecilia Rosada, Søren Kamp, Karin Stenderup, A M Fiehn, Tomas Norman Dam
Publikováno v: British Journal of Dermatology. 164:1017-1022
Summary Background The pathogenesis of hidradenitis suppurativa (HS) is not clearly understood. The nomenclature suggests an important role for the apocrine glands but recent evidence implicates the pilosebaceous unit as a more likely candidate to pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fce408688f201c8e7fc2177f2676224
https://doi.org/10.1111/j.1365-2133.2011.10224.x
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2
Stereological Estimation of Epidermal Volumes and Dermo-Epidermal Surface Area in Normal Skin
Autor: Gregor B.E. Jemec, Cecilia Rosada, T.N. Dam, L.S. Balkert, Kåre Kemp, Bente Pakkenberg, Søren Kamp, Karin Stenderup
Publikováno v: Kamp, S, Balkert, L S, Stenderup, K, Rosada, C, Pakkenberg, B, Kemp, K, Jemec, G & Dam, T N 2011, ' Stereological estimation of epidermal volumes and dermo-epidermal surface area in normal skin ', Dermatology, vol. 223, no. 2, pp. 131-9 . https://doi.org/10.1159/000330737
Quantitative morphological studies of the healthy epidermis are essential in providing a range of parameter estimates that can be considered within the range of normality. Stereology is a set of statistical tools that provides potentially unbiased an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b6c952def168e3adc660c9392ecf73
https://doi.org/10.1159/000330737
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3
Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model
Autor: Maria Jakobsen, Jacob Giehm Mikkelsen, Brian Moldt, Søren Kamp, Karin Stenderup, Tomas Norman Dam, Cecilia Rosada, Thomas G. Jensen
Publikováno v: Jakobsen, M, Stenderup, K, Rosada, C, Moldt, B, Kamp, S, Dam, T N, Jensen, T G & Mikkelsen, J G 2009, ' Amelioration of Psoriasis by Anti-TNF-alpha RNAi in the Xenograft Transplantation Model ', Molecular Therapy . https://doi.org/10.1038/mt.2009.141
Udgivelsesdato: 2009-Jun-30 Tumor necrosis factor-alpha (TNF-alpha) is upregulated in psoriatic skin and represents a prominent target in psoriasis treatment. The level of TNF-alpha-encoding mRNA, however, is not increased in psoriatic skin, and it r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42292534b4035962f75c0fb89d56d55
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4
Prodefensins are matrix proteins of specific granules in human neutrophils
Autor: Jero Calafat, Henrik Winther, Søren Kamp, Mikkel Faurschou, Anders H. Johnsen, Lene Udby, Jack B. Cowland, Niels Borregaard
Publikováno v: Journal of Leukocyte Biology. 78:785-793
Defensins are potent antimicrobial and proinflammatory peptides. The human neutrophil defensins human neutrophil peptide (HNP)-1–3 are synthesized as 94 amino acide (aa) preproHNPs, which are converted to 75 aa proHNPs by cotranslational removal of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf338145eb8b301226d838b68f9f7f9
https://doi.org/10.1189/jlb.1104688
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5
Targeting of human interleukin-12B by small hairpin RNAs in xenografted psoriatic skin
Autor: Rasmus O. Bak, Line Petersen, Brian Moldt, Cecilia Rosada, Thomas G. Jensen, Maria Jakobsen, Frederik Dagnæs-Hansen, Søren Kamp, Karin Stenderup, Jacob Giehm Mikkelsen, Tomas Norman Dam
Publikováno v: Bak, R O, Stenderup, K, Rosada, C, Petersen, L B, Moldt, B, Dagnæs-Hansen, F, Jakobsen, M, Kamp, S, Jensen, T G, Dam, T N & Mikkelsen, J G 2011, ' Targeting of human interleukin-12B by small hairpin RNAs in xenografted psoriatic skin ', B M C Dermatology, vol. 11, no. 1, pp. 5 . https://doi.org/10.1186/1471-5945-11-5
BMC Dermatology, Vol 11, Iss 1, p 5 (2011)
Publons
BMC Dermatology
Background Psoriasis is a chronic inflammatory skin disorder that shows as erythematous and scaly lesions. The pathogenesis of psoriasis is driven by a dysregulation of the immune system which leads to an altered cytokine production. Proinflammatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9ffd29e790075c93d373d6d3d6bd04
https://doi.org/10.1186/1471-5945-11-5
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6
Valrubicin in a topical formulation treats psoriasis in a xenograft transplantation model
Autor: Frederik Dagnæs-Hansen, Søren Kamp, Karin Stenderup, Elisabeth de Darkó, Tomas Norman Dam, Cecilia Rosada
Publikováno v: Rosada, C, Stenderup, K, de Darkó, E, Dagnaes-Hansen, F, Kamp, S & Dam, T N 2010, ' Valrubicin in a topical formulation treats psoriasis in a xenograft transplantation model ', Journal of Investigative Dermatology, vol. 130, no. 2, pp. 455-63 . https://doi.org/10.1038/jid.2009.277
Valrubicin is a cytostatic drug currently approved by the American Federal Drug Administration as a trademarked Valstar sterile solution for the treatment of bladder cancer. Valrubicin has shown an excellent therapeutic potential with minimal toxicit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88179ba2b3f0c3214629178482fbe3ab
https://pubmed.ncbi.nlm.nih.gov/19741712
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9
Partial Correction of Psoriasis upon Genetic Knock-Down of Human TNF-α by Lentivirus-Encoded shRNAs in a Xenograft Mouse Model
Autor: Maria Jakobsen, Karin Stenderup, Cecilia Rosada Kjeldsen, Brian Moldt, Søren Kamp, Tomas Norman Dam, Jensen, Thomas G., Jacob Giehm Mikkelsen
Publikováno v: Jakobsen, M, Stenderup, K, Rosada, C, Moldt, B, Kamp, S, Dam, T N, Jensen, T G & Mikkelsen, J G 2008, ' Partial Correction of Psoriasis upon Genetic Knock-Down of Human TNF-α by Lentivirus-Encoded shRNAs in a Xenograft Mouse Model ', Boston, Massachusetts, United States, 28/05/2008-01/06/2008, .
Aarhus University
The proinflammatory cytokine Tumor Necrosis Factor alpha (TNF-) is upregulated in inflammatory psoriatic skin. The increased level of TNF- protein is thought to cause keratinocyte hyperproliferation, leukocyte infiltration as well as growth and dilat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5558c71786adac9b182b6fd8afc7ec05
https://pure.au.dk/portal/da/publications/partial-correction-of-psoriasis-upon-genetic-knockdown-of-human-tnf-by-lentivirusencoded-shrnas-in-a-xenograft-mouse-model(9c66fdb0-1cd5-11dd-be51-000ea68e967b).html
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