Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Søren E. Pischke"'
Autor:
Eline de Boer, Marina Sokolova, Neeltina M. Jager, Camilla Schjalm, Marc G. Weiss, Olav M. Liavåg, Hanno Maassen, Harry van Goor, Ebbe Billmann Thorgersen, Kristin Pettersen, Dorte Christiansen, Judith Krey Ludviksen, Bente Jespersen, Tom E. Mollnes, Henri G. D. Leuvenink, Søren E. Pischke
Publikováno v:
Transplant International, Vol 37 (2024)
Normothermic machine perfusion (NMP) is a clinical strategy to reduce renal ischemia-reperfusion injury (IRI). Optimal NMP should restore metabolism and minimize IRI induced inflammatory responses. Microdialysis was used to evaluate renal metabolism.
Externí odkaz:
https://doaj.org/article/c476551ac52e4e81b7795f7c667c036c
Autor:
Torbjørn F. Heldal, Anders Åsberg, Thor Ueland, Anna V. Reisæter, Søren E. Pischke, Tom E. Mollnes, Pål Aukrust, Finn Reinholt, Anders Hartmann, Kristian Heldal, Trond G. Jenssen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundEarly graft loss following kidney transplantation is mainly a result of acute rejection or surgical complications, while long-term kidney allograft loss is more complex. We examined the association between systemic inflammation early after
Externí odkaz:
https://doaj.org/article/0bd26e24681644d4a40fdbb95d1ba58e
Autor:
Hanno Maassen, Leonie H. Venema, Marc G. Weiss, Tobias M. Huijink, H. Sijbrand Hofker, Anna K. Keller, Tom E. Mollnes, Marco Eijken, Søren E. Pischke, Bente Jespersen, Harry van Goor, Henri G. D. Leuvenink
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 749 (2023)
Kidney extraction time has a detrimental effect on post-transplantation outcome. This study aims to improve the flush-out and potentially decrease ischemic injury by the addition of hydrogen sulphide (H2S) to the flush medium. Porcine kidneys (n = 22
Externí odkaz:
https://doaj.org/article/883abdf9886d4ee194a43847362ce2fc
Autor:
Bartlomiej J. Witczak, Søren E. Pischke, Anna V. Reisæter, Karsten Midtvedt, Judith K. Ludviksen, Kristian Heldal, Trond Jenssen, Anders Hartmann, Anders Åsberg, Tom E. Mollnes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe major reason for graft loss is chronic tissue damage, as interstitial fibrosis and tubular atrophy (IF/TA), where complement activation may serve as a mediator. The association of complement activation in a stable phase early after kidn
Externí odkaz:
https://doaj.org/article/381cdef388294bcfa91422c31b67ebd6
Autor:
Hilde L. Orrem, Per H. Nilsson, Søren E. Pischke, Ola Kleveland, Arne Yndestad, Karin Ekholt, Jan K. Damås, Terje Espevik, Bjørn Bendz, Bente Halvorsen, Ida Gregersen, Rune Wiseth, Geir Ø. Andersen, Thor Ueland, Lars Gullestad, Pål Aukrust, Andreas Barratt-Due, Tom E. Mollnes
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Elevated interleukin-6 (IL-6) and complement activation are associated with detrimental effects of inflammation in coronary artery disease (CAD). The complement anaphylatoxins C5a and C3a interact with their receptors; the highly inflamma
Externí odkaz:
https://doaj.org/article/b43390071e8c48b390a28360a21eee93
Autor:
Torbjørn Fossum Heldal, Anders Åsberg, Thor Ueland, Anna Varberg Reisæter, Søren E. Pischke, Tom Eirik Mollnes, Pål Aukrust, Anders Hartmann, Kristian Heldal, Trond Jenssen
Publikováno v:
American Journal of Transplantation
In the general population, low-grade inflammation has been established as a risk factor for all-cause mortality. We hypothesized that an inflammatory milieu beyond the time of recovery from the surgical trauma could be associated with increased long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7e5cf2aa897db764cb8b3e2764968a
http://hdl.handle.net/10852/94916
http://hdl.handle.net/10852/94916
Autor:
Anub Mathew Thomas, Viktoriia Chaban, Søren E. Pischke, Hilde Lang Orrem, Vidar Bosnes, Kjetil Sunde, Ingebjørg Seljeflot, Christofer Lundqvist, Espen Rostrup Nakstad, Geir Øystein Andersen, Camilla Schjalm, Tom Eirik Mollnes, Andreas Barratt-Due
Publikováno v:
Molecular Immunology
Background Complement activation plays an important pathogenic role in numerous diseases. The ratio between an activation product and its parent protein is suggested to be more sensitive to detect complement activation than the activation product its
Autor:
Eline de Boer, Marina Sokolova, Huy Q. Quach, Karin E. McAdam, Maximilian P. Götz, Viktoriia Chaban, Jarle Vaage, Beatrice Fageräng, Trent M. Woodruff, Peter Garred, Per H. Nilsson, Tom E. Mollnes, Søren E. Pischke
Publikováno v:
Journal of Immunology
Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG motifs and the complement sys