ProtecT-2-D trial protocol: cardiovascular protection in patients with type 2 diabetes and established heart and/or vascular disease at a cardio-metabolic clinic—a randomized controlled trial

Autor: Katrine Schultz Overgaard, Roda Abdulkadir Mohamed, Thomas Rueskov Andersen, Jess Lambrechtsen, Kenneth Egstrup, Søren Auscher

Publikováno v: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-10 (2024)

Abstract Background Cardiovascular disease remains the primary cause of morbidity and mortality despite advancements in the treatment of patients with type 2 diabetes. Effective diabetes management extends beyond blood glucose control and includes ca

Externí odkaz: https://doaj.org/article/3524db430a8f4125b373ff737ad8a5ee

Liraglutide treatment is associated with progression of coronary artery fibrous plaque: a prospective 1-year follow-up study in asymptomatic patients with type 2 diabetes

Autor: Laurits Juhl Heinsen, Gokulan Pararajasingam, Thomas Rueskov Andersen, Søren Auscher, Hussam Mahmoud Sheta, Helle Precht, Kalle Brunebjerg Engdam, Jørgen Hangaard, Jess Lambrechtsen, Filip Krag Knop, Kenneth Egstrup

Publikováno v: BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-8 (2023)

Abstract Objective The objective of this study was to assess the association between clinically indicated liraglutide treatment and coronary artery plaque progression during 1-year follow-up in asymptomatic diabetes. Methods Patients were divided int

Externí odkaz: https://doaj.org/article/ddc0534d48a74cd386c3f12f3cdb4150

High-risk coronary artery plaque in asymptomatic patients with type 2 diabetes: clinical risk factors and coronary artery calcium score

Autor: Laurits Juhl Heinsen, Gokulan Pararajasingam, Thomas Rueskov Andersen, Søren Auscher, Hussam Mahmoud Sheta, Helle Precht, Jess Lambrechtsen, Kenneth Egstrup

Publikováno v: Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-11 (2021)

Abstract Background High-risk coronary artery plaque (HRP) is associated with increased risk of acute coronary syndrome. We aimed to investigate the prevalence of HRP in asymptomatic patients with type 2 diabetes (T2D), and its relation to patient ch

Externí odkaz: https://doaj.org/article/81646d1b146349fda230ab963f8cfa89

Dysglycemia and increased left ventricle mass in normotensive patients admitted with a first myocardial infarction: prognostic implications of dysglycemia during 14 years of follow-up

Autor: Gokulan Pararajasingam, Brian Bridal Løgstrup, Dan Eik Høfsten, Thomas Brøcher Christophersen, Søren Auscher, Jørgen Hangaard, Kenneth Egstrup

Publikováno v: BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-12 (2019)

Abstract Background Left ventricle mass (LVM) can be influenced by various conditions including hypertension and/or inherent cardiomyopathies. Dysglycemia is also thought to exert an anabolic effect on heart tissue by hyperinsulinemia and thereby pro

Externí odkaz: https://doaj.org/article/fcaf53e78f0f49f0a30e5c0ad6dfef28

Diabetic microvascular complications are associated with reduced global longitudinal strain independent of atherosclerotic coronary artery disease in asymptomatic patients with diabetes mellitus: a cross-sectional study

Autor: Laurits Juhl Heinsen, Gokulan Pararajasingam, Johanna Larsson, Thomas Rueskov Andersen, Rasmus Møgelvang, Jørgen Hangaard, Søren Auscher, Kenneth Egstrup, Brian Bridal Løgstrup

Publikováno v: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-13 (2021)
Pararajasingam, G, Heinsen, L J, Larsson, J, Andersen, T R, Løgstrup, B B, Auscher, S, Hangaard, J, Møgelvang, R & Egstrup, K 2021, ' Diabetic microvascular complications are associated with reduced global longitudinal strain independent of atherosclerotic coronary artery disease in asymptomatic patients with diabetes mellitus : a cross-sectional study ', BMC Cardiovascular Disorders, vol. 21, 269 . https://doi.org/10.1186/s12872-021-02063-w
BMC Cardiovascular Disorders

Background Reduced left ventricular function, assessed by global longitudinal strain (GLS), is sometimes observed in asymptomatic patients with diabetes mellitus (DM) and is often present in patients with diabetes-related microvascular complications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7354a22018e22dd02e46833531a7fd88
https://doaj.org/article/b481711d27914233843a352a05a27001