Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Søren Astrup Jørgensen"'
Autor:
Pernille Barbre Pedersen, Ragna Berthelsen, Thomas Rades, Søren Astrup Jørgensen, Peter Vilmann, Daniel Bar-Shalom, Stefania Baldursdottir, Anette Müllertz
Publikováno v:
Pedersen, P B, Berthelsen, R, Rades, T, Jørgensen, S A, Vilmann, P, Bar-Shalom, D, Baldursdottir, S & Müllertz, A 2022, ' Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine ', International Journal of Pharmaceutics, vol. 622, 121856 . https://doi.org/10.1016/j.ijpharm.2022.121856
To elucidate the critical parameters affecting drug dissolution in the human stomach, the intrinsic dissolution rate (IDR) of cinnarizine was determined in aspirated and simulated human gastric fluids (HGF). Fasted aspirated HGF (aspHGF) was collecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b5b70034ebab6407f1b59e00362b8a
https://curis.ku.dk/portal/da/publications/physicochemical-characterization-of-aspirated-and-simulated-human-gastric-fluids-to-study-their-influence-on-the-intrinsic-dissolution-rate-of-cinnarizine(32ec6d42-b295-4877-ba95-c8bd6bc3ad65).html
https://curis.ku.dk/portal/da/publications/physicochemical-characterization-of-aspirated-and-simulated-human-gastric-fluids-to-study-their-influence-on-the-intrinsic-dissolution-rate-of-cinnarizine(32ec6d42-b295-4877-ba95-c8bd6bc3ad65).html
Autor:
Anette Müllertz, Andrew Leithead, Thomas Rades, Kung-I Feng, Søren Astrup Jørgensen, Nicole Canfield, Cecilie Maria Madsen
Publikováno v:
European Journal of Pharmaceutical Sciences. 111:311-319
The composition of the human intestinal fluids varies both intra- and inter-individually. This will influence the solubility of orally administered drug compounds, and hence, the absorption and efficacy of compounds displaying solubility limited abso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d3a6f461c7bd5de57cef2e3f30200c
https://doi.org/10.1016/j.ejps.2017.10.003
https://doi.org/10.1016/j.ejps.2017.10.003
