Duration of Device-Based Fever Prevention after Cardiac Arrest

Autor: Christian Hassager, Henrik Schmidt, Jacob E. Møller, Johannes Grand, Simon Mølstrøm, Rasmus P. Beske, Søren Boesgaard, Britt Borregaard, Ditte Bekker-Jensen, Jordi S. Dahl, Martin S. Frydland, Dan E. Høfsten, Yusuf A. Isse, Jakob Josiassen, Vibeke R. Lind Jørgensen, Daniel Kondziella, Matias G. Lindholm, Emil Moser, Benjamin C. Nyholm, Laust E.R. Obling, Laura Sarkisian, Frederik T. Søndergaard, Jakob H. Thomsen, Jens J. Thune, Søren Venø, Sebastian C. Wiberg, Matilde Winther-Jensen, Martin A.S. Meyer, Jesper Kjaergaard

Publikováno v: New England Journal of Medicine. 388:888-897

Guidelines recommend active fever prevention for 72 hours after cardiac arrest. Data from randomized clinical trials of this intervention have been lacking.We randomly assigned comatose patients who had been resuscitated after an out-of-hospital card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b95bb794d93f48be75d34c35f2ece49
https://doi.org/10.1056/nejmoa2212528

Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC

Autor: Marta Pérez-Hernández, Chantal J.M. van Opbergen, Navratan Bagwan, Christoffer Rasmus Vissing, Grecia M. Marrón-Liñares, Mingliang Zhang, Estefania Torres Vega, Andrea Sorrentino, Lylia Drici, Karolina Sulek, Ruxu Zhai, Finn B. Hansen, Alex Hørby Christensen, Søren Boesgaard, Finn Gustafsson, Kasper Rossing, Eric M. Small, Michael J. Davies, Eli Rothenberg, Priscila Y. Sato, Marina Cerrone, Thomas Hartvig Lindkær Jensen, Klaus Qvortrup, Henning Bundgaard, Mario Delmar, Alicia Lundby

Publikováno v: Circulation. 146(11)

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by high propensity to life-threatening arrhythmias and progressive loss of heart muscle. More than 40% of reported genetic variants linked to ARVC reside in the PKP2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edd7414fa4b54f3858bd75e129cda12
https://pubmed.ncbi.nlm.nih.gov/35959657

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

Autor: Jesper Kjaergaard, Jacob E. Møller, Henrik Schmidt, Johannes Grand, Simon Mølstrøm, Britt Borregaard, Søren Venø, Laura Sarkisian, Dmitry Mamaev, Lisette O. Jensen, Benjamin Nyholm, Dan E. Høfsten, Jakob Josiassen, Jakob H. Thomsen, Jens J. Thune, Laust E.R. Obling, Matias G. Lindholm, Martin Frydland, Martin A.S. Meyer, Matilde Winther-Jensen, Rasmus P. Beske, Ruth Frikke-Schmidt, Sebastian Wiberg, Søren Boesgaard, Søren A. Madsen, Vibeke L. Jørgensen, Christian Hassager

Publikováno v: Kjaergaard, J, Møller, J E, Schmidt, H, Grand, J, Mølstrøm, S, Borregaard, B, Venø, S, Sarkisian, L, Mamaev, D, Jensen, L O, Nyholm, B, Høfsten, D E, Josiassen, J, Thomsen, J H, Thune, J J, Obling, L E R, Lindholm, M G, Frydland, M, Meyer, M A S, Winther-Jensen, M, Beske, R P, Frikke-Schmidt, R, Wiberg, S, Boesgaard, S, Madsen, S A, Jørgensen, V L & Hassager, C 2022, ' Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest ', New England Journal of Medicine, vol. 387, no. 16, pp. 1456-1466 . https://doi.org/10.1056/NEJMoa2208687

Evidence to support the choice of blood-pressure targets for the treatment of comatose survivors of out-of-hospital cardiac arrest who are receiving intensive care is limited.In a double-blind, randomized trial with a 2-by-2 factorial design, we eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16d7749fc0a0a7bacf2121e209f7ce0
https://pubmed.ncbi.nlm.nih.gov/36260797

Three decades of heart transplantation: experience and long-term outcome

Autor: Lærke Marie Nelson, Kasper Rossing, Søren Boesgaard, Hasse Møller-Sørensen, Christian Holdflod Møller, Finn Gustafsson, Peter Skov Olsen

Publikováno v: Nelson, L M, Rossing, K, Boesgaard, S, Møller-Sørensen, H, Møller, C H, Gustafsson, F & Olsen, P S 2022, ' Three decades of heart transplantation : experience and long-term outcome ', Scandinavian Cardiovascular Journal, vol. 56, no. 1, pp. 65-72 . https://doi.org/10.1080/14017431.2022.2061726

Objectives. Heart transplantation (HTx) has become an established treatment option in patients with end-stage heart failure. The aim of this study was to report on long-term outcome over the past three decades. Design. Consecutive adult patients rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19b22d52aecd044bc03bf91c9541377
https://pubmed.ncbi.nlm.nih.gov/35481404

Socioeconomic Disparities in Referral for Invasive Hemodynamic Evaluation for Advanced Heart Failure: A Nationwide Cohort Study

Autor: Morten Schou, Søren Boesgaard, Lars Køber, Kasper Rossing, Finn Gustafsson, C. Madelaire, Søren Lund Kristensen, Johan Larsson

Publikováno v: Larsson, J, Kristensen, S L, Madelaire, C, Schou, M, Rossing, K, Boesgaard, S, Køber, L & Gustafsson, F 2021, ' Socioeconomic Disparities in Referral for Invasive Hemodynamic Evaluation for Advanced Heart Failure : A Nationwide Cohort Study ', Circulation. Heart Failure, vol. 14, no. 10, e008662 . https://doi.org/10.1161/CIRCHEARTFAILURE.121.008662

Background: Factors determining referral for advanced heart failure (HF) evaluation are poorly studied. We studied the influence of socioeconomic aspects on the referral process in Denmark, which has a taxpayer-funded national health care system. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fa9f0397beb58bc6278abcdb819e06
https://doi.org/10.1161/circheartfailure.121.008662