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Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents

Autor: Blindheim, Fredrik Heen, Olsen, Cecilie Elisabeth, Søgaard, Caroline Krogh, Otterlei, Marit, Sundby, Eirik, Hoff, Bård Helge

Externí odkaz: https://hdl.handle.net/11250/3105203

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"Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling

Autor: Søgaard, Caroline Krogh, Blindheim, Augun, Røst, Lisa Marie, Petrovic, Voin, Nepal, Anala, Bachke, Siri, Liabakk, Nina-Beate, Gederaas, Odrun Arna, Viset, Trond, Arum, Carl-Jørgen, Bruheim, Per, Otterlei, Marit

Externí odkaz: http://hdl.handle.net/11250/2586614

"Two hits - one stone"; increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling.

Autor: Søgaard CK; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Clinic of Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Blindheim A; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Department of Urology and Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Røst LM; Department of Biotechnology and Food Science, NTNU, Trondheim, Norway., Petrović V; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Nepal A; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Bachke S; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Liabakk NB; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Gederaas OA; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Viset T; Department of Pathology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Arum CJ; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Department of Urology and Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Bruheim P; Department of Biotechnology and Food Science, NTNU, Trondheim, Norway., Otterlei M; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Clinic of Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.; APIM Therapeutics A/S, Trondheim, Norway.

Publikováno v: Oncotarget [Oncotarget] 2018 Aug 21; Vol. 9 (65), pp. 32448-32465. Date of Electronic Publication: 2018 Aug 21 (Print Publication: 2018).