Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sören Reinhard"'
Autor:
Veria Khosrawipour, Sören Reinhard, Alice Martino, Tanja Khosrawipour, Mohamed Arafkas, Agata Mikolajczyk
Publikováno v:
International Journal of Surgical Oncology, Vol 2019 (2019)
Background. High‐intensity ultrasound (HIUS) has been studied for the past two decades as a new therapeutic option for solid tumor direct treatment and a method for better chemotherapy delivery and perfusion. This treatment approach has not been te
Externí odkaz:
https://doaj.org/article/dd2b7dc06a36425f9a5d285b1fd6a72f
Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles
Autor:
Lisa Haddick, Wei Zhang, Sören Reinhard, Karin Möller, Hanna Engelke, Ernst Wagner, Thomas Bein
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 505 (2020)
Multifunctional core-shell mesoporous silica nanoparticles (MSN) were tailored in size ranging from 60 to 160 nm as delivery agents for antitumoral microRNA (miRNA). The positively charged particle core with a pore diameter of about 5 nm and a stella
Externí odkaz:
https://doaj.org/article/c0358f73583d491ea7726b8847214426
Autor:
Roland E. Kälin, Rainer Glass, Josefine Radke, Jörg-Christian Tonn, Ulrich Schüller, Dolores Hambardzumyan, Rolf Bjerkvig, Michel Mittelbronn, Ernst Wagner, Josef M. Penninger, Patrick N. Harter, Angelo L. Vescovi, Michael Synowitz, Gaetano Gargiulo, Katharina Eisenhut, Susanne Kleber, Christel C. Herold-Mende, Sören Reinhard, Hrvoje Miletic, Marie N.M. Volmar, Nina Zdouc, Veit M. Stoecklein, Min Li, Mengzhuo Hou, Giorgia Mastrella
Apelin is expressed in tumor vessels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1846a4f7053adb8094d803ad8c400655
https://doi.org/10.1158/0008-5472.22423526
https://doi.org/10.1158/0008-5472.22423526
Autor:
Roland E. Kälin, Rainer Glass, Josefine Radke, Jörg-Christian Tonn, Ulrich Schüller, Dolores Hambardzumyan, Rolf Bjerkvig, Michel Mittelbronn, Ernst Wagner, Josef M. Penninger, Patrick N. Harter, Angelo L. Vescovi, Michael Synowitz, Gaetano Gargiulo, Katharina Eisenhut, Susanne Kleber, Christel C. Herold-Mende, Sören Reinhard, Hrvoje Miletic, Marie N.M. Volmar, Nina Zdouc, Veit M. Stoecklein, Min Li, Mengzhuo Hou, Giorgia Mastrella
APLN co-expressed genes are enriched for angiogenesis in glioblastoma subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8832339fdd710cb706693f1f838b12
https://doi.org/10.1158/0008-5472.22423520
https://doi.org/10.1158/0008-5472.22423520
Autor:
Roland E. Kälin, Rainer Glass, Josefine Radke, Jörg-Christian Tonn, Ulrich Schüller, Dolores Hambardzumyan, Rolf Bjerkvig, Michel Mittelbronn, Ernst Wagner, Josef M. Penninger, Patrick N. Harter, Angelo L. Vescovi, Michael Synowitz, Gaetano Gargiulo, Katharina Eisenhut, Susanne Kleber, Christel C. Herold-Mende, Sören Reinhard, Hrvoje Miletic, Marie N.M. Volmar, Nina Zdouc, Veit M. Stoecklein, Min Li, Mengzhuo Hou, Giorgia Mastrella
Antiangiogenic therapy of glioblastoma (GBM) with bevacizumab, a VEGFA-blocking antibody, may accelerate tumor cell invasion and induce alternative angiogenic pathways. Here we investigate the roles of the proangiogenic apelin receptor APLNR and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a50ffe150cec046f2da683997978d96
https://doi.org/10.1158/0008-5472.c.6511514.v1
https://doi.org/10.1158/0008-5472.c.6511514.v1
Autor:
Joachim Justad Røise, Hesong Han, Jie Li, D. Lucas Kerr, Chung Taing, Kamyar Behrouzi, Maomao He, Emily Ruan, Lienna Y. Chan, Eli M. Espinoza, Sören Reinhard, Kanav Thakker, Justin Kwon, Mohammad R. K. Mofrad, Niren Murthy
Publikováno v:
Molecular Pharmaceutics. 19:67-79
The development of endosomal disruptive agents is a major challenge in the field of drug delivery and pharmaceutical chemistry. Current endosomal disruptive agents are composed of polymers, peptides, and nanoparticles and have had limited clinical im
Autor:
Marek Pieczka, Mohamed Arafkas, Alessio Pigazzi, Tanja Khosrawipour, Alice Martino, Sören Reinhard, Veria Khosrawipour, Jacek Bania, Justyna Schubert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
For decades, intraperitoneal chemotherapy (IPC) was delivered into the abdominal cavity as a liquid solution. This preliminary study aims to evaluate foam as a potential new drug carrier for IPC delivery. Foam-based intraperitoneal chemotherapy (FBIC
Autor:
Hesong Han, Hye Young Lee, Joachim Justad Røise, Niren Murthy, I-Che Li, Jie Li, Sören Reinhard, Jan Tuma
Publikováno v:
Chemical Communications. 56:14207-14210
There is great interest in developing strategies to deliver proteins into the cytoplasm of cells. We report here a PEG-poly-eosin block copolymer (PEG-pEosin) that can encapsulate proteins and release them in active form under mildly acidic condition
Autor:
Sören Reinhard, Ernst Wagner
Publikováno v:
Nanoparticles for Brain Drug Delivery ISBN: 9781003119326
Nanoparticles for Brain Drug Delivery
Nanoparticles for Brain Drug Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ced1adbfa470894c0a0144f49b5d06
https://doi.org/10.1201/9781003119326-11
https://doi.org/10.1201/9781003119326-11
Publikováno v:
Bioconjugate Chemistry. 29:3649-3657
Sequence-defined cationic lipo-oligomers are potent siRNA carriers, forming stable lipo-polyplexes based on both electrostatic and hydrophobic interactions and, after endocytosis and endosomal protonation, facilitating the delivery of siRNA into the