Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sören Lukassen"'
Autor:
Maik Pietzner, Robert Lorenz Chua, Eleanor Wheeler, Katharina Jechow, Julian D. S. Willett, Helena Radbruch, Saskia Trump, Bettina Heidecker, Hugo Zeberg, Frank L. Heppner, Roland Eils, Marcus A. Mall, J. Brent Richards, Leif-Erik Sander, Irina Lehmann, Sören Lukassen, Nicholas J. Wareham, Christian Conrad, Claudia Langenberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Genetic factors have been found to be associated with severe COVID-19. Here, the authors integrated genomic, proteomic, and single-cell data to identify ELF5 as a candidate risk gene with a possible role in respiratory epithelial cells, which are tar
Externí odkaz:
https://doaj.org/article/7bddc4d6d42748edbe382377dc878d84
Autor:
Foo Wei Ten, Dongsheng Yuan, Nabil Jabareen, Yin Jun Phua, Roland Eils, Sören Lukassen, Christian Conrad
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Feature identification and manual inspection is currently still an integral part of biological data analysis in single-cell sequencing. Features such as expressed genes and open chromatin status are selectively studied in specific contexts, cell stat
Externí odkaz:
https://doaj.org/article/b02bbcd6ab174203b37dc2701d23b875
Autor:
Jessica Denise Schwarz, Sören Lukassen, Pranjali Bhandare, Lorenz Eing, Marteinn Thor Snaebjörnsson, Yiliam Cruz García, Jan Philipp Kisker, Almut Schulze, Elmar Wolf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cellular growth is a fundamental process of life and must be precisely controlled in multicellular organisms. Growth is crucially controlled by the number of functional ribosomes available in cells. The production of new ribosomes depends critically
Externí odkaz:
https://doaj.org/article/89c05fdd745a45f78a80af68cbaedfcd
Autor:
Bruce Schultz, Andrea Zaliani, Christian Ebeling, Jeanette Reinshagen, Denisa Bojkova, Vanessa Lage-Rupprecht, Reagon Karki, Sören Lukassen, Yojana Gadiya, Neal G. Ravindra, Sayoni Das, Shounak Baksi, Daniel Domingo-Fernández, Manuel Lentzen, Mark Strivens, Tamara Raschka, Jindrich Cinatl, Lauren Nicole DeLong, Phil Gribbon, Gerd Geisslinger, Sandra Ciesek, David van Dijk, Steve Gardner, Alpha Tom Kodamullil, Holger Fröhlich, Manuel Peitsch, Marc Jacobs, Julia Hoeng, Roland Eils, Carsten Claussen, Martin Hofmann-Apitius
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing.
Externí odkaz:
https://doaj.org/article/18b0a7d14b824058a3306b2a9990465c
Autor:
Vladimir G. Magalhães, Sören Lukassen, Maike Drechsler, Jennifer Loske, Sandy S. Burkart, Sandra Wüst, Eva-Maria Jacobsen, Jobst Röhmel, Marcus A. Mall, Klaus-Michael Debatin, Roland Eils, Stella Autenrieth, Aleš Janda, Irina Lehmann, Marco Binder
To cope with novel virus infections to which no prior adaptive immunity exists, the body strongly relies on the innate immune system. In such cases, including infections with SARS-CoV-2, children tend to fair better than adults. In the context of COV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c77e4fed6b9d3acc85255cc93877d01
https://doi.org/10.1101/2023.05.17.541103
https://doi.org/10.1101/2023.05.17.541103
Autor:
Luis P. Kuschel, Jürgen Hench, Stephan Frank, Ivana Bratic Hench, Elodie Girard, Maud Blanluet, Julien Masliah‐Planchon, Martin Misch, Julia Onken, Marcus Czabanka, Dongsheng Yuan, Sören Lukassen, Philipp Karau, Naveed Ishaque, Elisabeth G. Hain, Frank Heppner, Ahmed Idbaih, Nikolaus Behr, Christoph Harms, David Capper, Philipp Euskirchen
Publikováno v:
Neuropathology and Applied Neurobiology. 49
DNA methylation-based classification of cancer provides a comprehensive molecular approach to diagnose tumours. In fact, DNA methylation profiling of human brain tumours already profoundly impacts clinical neuro-oncology. However, current implementat
Autor:
Simon Völkl, Julia Moosmann, Andreas Mackensen, Okan Toka, Arif B. Ekici, Sven Dittrich, Sören Lukassen
Publikováno v:
The Thoracic and Cardiovascular Surgeon
Background Protein-losing enteropathy (PLE) is a severe complication of the Fontan circulation. There is increasing discussion about whether lymphatic dysregulation is involved as pathomechanism of PLE. This investigation focuses on the interplay bet
Autor:
Sayoni Das, Daniel Domingo-Fernández, Jindrich Cinatl, Manuel C. Peitsch, Sandra Ciesek, Martin Hofmann-Apitius, Shounak Baksi, Gerd Geisslinger, Bruce T. Schultz, P. Gribbon, Tamara Raschka, Julia Hoeng, Marc Jacobs, David van Dijk, Christian Ebeling, Manuel Lentzen, Roland Eils, Mark Strivens, Steve Gardner, Holger Fröhlich, Alpha Tom Kodamullil, Yojana Gadiya, Neal G. Ravindra, Jeanette Reinshagen, Vanessa Lage-Rupprecht, Carsten Claussen, Reagon Karki, Denisa Bojkova, Sören Lukassen, Andrea Zaliani, Lauren Nicole DeLong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing. However,
Autor:
Nils Lachmann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Linda Marie Laura Thole, Diana Stauch, Andreas Diefenbach, Tomasz Zemojtel, Katharina Jechow, Sören Lukassen, Alexander Potekhin, Katja Kotsch, Mira Choi, Yasmin Bergmann, Vanessa Proß, Oliver Hölsken, Ulrike Weber, Christian Conrad, Fabian Halleck, Caroline Tizian, Eva Schrezenmeier, Klemens Budde, Elena Storz, Friederike Bachmann, Henriette Straub-Hohenbleicher, Arne Sattler
Publikováno v:
Journal of Clinical Investigation
Novel mRNA-based vaccines have been proven powerful tools to combat the global pandemic caused by SARS-CoV2 with BNT162b2 efficiently protecting individuals from COVID-19 across a broad age range. Still, it remains largely unknown how renal insuffici
Autor:
Bruce T. Schultz, Daniel Domingo-Fernández, Sayoni Das, Sandra Ciesek, Christian Ebeling, P. Gribbon, David van Dijk, Yojana Gadiya, Holger Fröhlich, Shounak Baksi, Manuel C. Peitsch, Jindrich Cinatl, Julia Hoeng, Lauren Nicole DeLong, Martin Hofmann-Apitius, Andrea Zaliani, Alpha Tom Kodamullil, Mark Strivens, Gerd Geisslinger, Marc Jacobs, Roland Eils, Tamara Raschka, Jeanette Reinshagen, Manuel Lentzen, Reagon Karki, Neal G. Ravindra, Denisa Bojkova, Sören Lukassen, Carsten Claussen, Vanessa Lage-Rupprecht, Steve Gardner
The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::314730c0a8a164d5480e2330c2a520a9
https://doi.org/10.1101/2020.09.23.308239
https://doi.org/10.1101/2020.09.23.308239