Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sören Gregersen"'
Autor:
Zheer Kejlberg Al-Mashhadi, Rikke Viggers, Rasmus Fuglsang-Nielsen, Peter Vestergaard, Søren Gregersen, Jakob Starup-Linde
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundType 2 diabetes mellitus (T2D) is associated with an increased fracture risk. There is little evidence for the effects of glucagon-like peptide 1 receptor agonists (GLP-1RA) on fracture risk in T2D. We aimed to investigate the risk of major
Externí odkaz:
https://doaj.org/article/ebfcb6798f3142cbac0d9f552dcd758c
Autor:
Xiao-Jun Xu, Silvana Consolo, Katarina Bedecs, Zsuzsanna Wiesenfeld-Hallin, Rebecca L. Corwin, Tiit Land, P. Girotti, Siv Andell, Jacqueline N. Crawley, Tomas Hökfelt, Bo Ahrén, Ülo Langel, Sören Gregersen, Tamas Bartfai
Publikováno v:
Proceedings of the National Academy of Sciences. 90:11287-11291
The galanin-receptor ligand M40 [galanin-(1-12)-Pro3-(Ala-Leu)2-Ala amide] binds with high affinity to [mono[125I]iodo-Tyr26]galanin-binding sites in hippocampal, hypothalamic, and spinal cord membranes and in membranes from Rin m5F rat insulinoma ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa85bcf25cf61e2beb9a61b55c1c191
https://doi.org/10.1073/pnas.90.23.11287
https://doi.org/10.1073/pnas.90.23.11287
Publikováno v:
European Journal of Pharmacology. 232:35-39
The neuropeptide galanin occurs in pancreatic adrenergic nerves and has been suggested to be the adrenergic mediator of the stress-induced inhibition of insulin release. To study its physiological function, we recently synthesized a galanin-like gala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03dfedba0bb4396d18812160d6dfa3c
https://doi.org/10.1016/0014-2999(93)90725-w
https://doi.org/10.1016/0014-2999(93)90725-w
Autor:
Zheer Kejlberg Al-Mashhadi, Rikke Viggers, Jakob Starup-Linde, Peter Vestergaard, Søren Gregersen
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundType 2 diabetes mellitus (T2D) is associated with an increased fracture risk. It is debated whether sodium-glucose cotransporter 2 (SGLT2) inhibitors influence fracture risk in T2D. We aimed to investigate the risk of major osteoporotic fra
Externí odkaz:
https://doaj.org/article/f22056d0f41b4c79a2c7d484322234ac
Autor:
Jakob Starup-Linde, Marie Juul Ornstrup, Thomas Nordstrøm Kjær, Simon Lykkeboe, Aase Handberg, Søren Gregersen, Torben Harsløf, Steen Bønløkke Pedersen, Peter Vestergaard, Bente Lomholt Langdahl
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveMetabolic syndrome (MetS), type 1 diabetes (T1D), and type 2 diabetes, are associated with an increased risk of fractures; however, the impact of obesity on bone deficits in diabetes is unknown. We aimed to compare markers of bone structure,
Externí odkaz:
https://doaj.org/article/b6e8e585bf594021adcf03f5eebf960f
Autor:
Rasmus Fuglsang-Nielsen, Elin Rakvaag, Peter Vestergaard, Kjeld Hermansen, Søren Gregersen, Jakob Starup-Linde
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundWhile osteoporosis is characterized by skeletal fragility due to increased bone turnover and low bone mineral density (BMD), subjects with abdominal obesity and type-2 diabetes have increased risk of bone fractures despite low bone turnover
Externí odkaz:
https://doaj.org/article/63621d9e931b4c5d811996ed5ad1e014
Galanin message-associated polypeptide (GMAP) does not affect insulin secretion from isolated islets
Publikováno v:
European journal of pharmacology. 259(1)
Galanin message-associated polypeptide (GMAP) is processed from preprogalanin. Recently, GMAP-like immunoreactivity was demonstrated in insulin cells in the endocrine pancreas. We therefore examined whether synthetic rat GMAP, like galanin, inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6da63846e4d3f78b1e97c13ca3c21a7
https://pubmed.ncbi.nlm.nih.gov/7525312
https://pubmed.ncbi.nlm.nih.gov/7525312
Publikováno v:
European journal of pharmacology. 203(1)
The 29-amino acid neuropeptide galanin occurs in intrapancreatic nerves and inhibits insulin secretion. To study the structure-activity relations of galanin, we examined the effects of pig and rat galanin, three galanin fragments (galanin-(1-11), gal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41e51bf0b2c0268fe459f44af2876d0
https://pubmed.ncbi.nlm.nih.gov/1724652
https://pubmed.ncbi.nlm.nih.gov/1724652
Autor:
Wenqian Gu, Andreas Rebsdorf, Camilla Anker, Søren Gregersen, Kjeld Hermansen, Jan M. C. Geuns, Per Bendix Jeppesen
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 2, Iss 4, Pp n/a-n/a (2019)
Abstract Aims Steviol glycosides are the sweet components extracted from medicinal plant Stevia rebaudiana Bertoni, which have antihyperglycaemic effects. Steviol glucuronide (SVG) is the metabolite excreted in human urine after oral administration o
Externí odkaz:
https://doaj.org/article/040ec326fe8249a7a7f2f7e3aa1ea7c7
Autor:
Jakob Starup-Linde, Sidse Westberg-Rasmussen, Simon Lykkeboe, Aase Handberg, Bolette Hartmann, Jens J. Holst, Kjeld Hermansen, Peter Vestergaard, Søren Gregersen
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Aim: Osteocalcin and undercarboxylated osteocalcin are suggested to be endocrine messengers from the bones and have been shown to stimulate insulin secretion from pancreatic β-cells. Insulin is hypothesized to increase the osteoblastic production of
Externí odkaz:
https://doaj.org/article/f154ae0793b04c68897b985d4279fd36