Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sönke Harder"'
Autor:
Jana Willim, Daniel Woike, Daniel Greene, Sarada Das, Kevin Pfeifer, Weimin Yuan, Anika Lindsey, Omar Itani, Amber L. Böhme, Debora Tibbe, Hans-Hinrich Hönck, Fatemeh Hassani Nia, Undiagnosed Diseases Network, Michael Zech, Theresa Brunet, Laurence Faivre, Arthur Sorlin, Antonio Vitobello, Thomas Smol, Cindy Colson, Kristin Baranano, Krista Schatz, Allan Bayat, Kelly Schoch, Rebecca Spillmann, Erica E. Davis, Erin Conboy, Francesco Vetrini, Konrad Platzer, Sonja Neuser, Janina Gburek-Augustat, Alexandra Noel Grace, Bailey Mitchell, Alexander Stegmann, Margje Sinnema, Naomi Meeks, Carol Saunders, Maxime Cadieux-Dion, Juliane Hoyer, Julien Van-Gils, Jean-Madeleine de Sainte-Agathe, Michelle L. Thompson, E. Martina Bebin, Monika Weisz-Hubshman, Anne-Claude Tabet, Alain Verloes, Jonathan Levy, Xenia Latypova, Sönke Harder, Gary A. Silverman, Stephen C. Pak, Tim Schedl, Kathleen Freson, Andrew Mumford, Ernest Turro, Christian Schlein, Vandana Shashi, Hans-Jürgen Kreienkamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Members of the leucine rich repeat (LRR) and PDZ domain (LAP) protein family are essential for animal development and histogenesis. Densin-180, encoded by LRRC7, is the only LAP protein selectively expressed in neurons. Densin-180 is a posts
Externí odkaz:
https://doaj.org/article/fa7e561bde0647a3a38569265135f1c2
Autor:
Aikaterini Laskou, Eva B. Znalesniak, Sönke Harder, Hartmut Schlüter, Dörthe Jechorek, Kathrin Langer, Carina Strecker, Claudia Matthes, Svetlana N. Tchaikovski, Werner Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2287 (2024)
TFF3 is a typical secretory poplypeptide of mucous epithelia belonging to the trefoil factor family (TFF) of lectins. In the intestine, respiratory tract, and saliva, TFF3 mainly exists as a high-molecular-mass complex with IgG Fc binding protein (FC
Externí odkaz:
https://doaj.org/article/da7b258381c04058ad6c07ede8ffdd9d
Autor:
Maria Thürmer, André Gollowitzer, Helmut Pein, Konstantin Neukirch, Elif Gelmez, Lorenz Waltl, Natalie Wielsch, René Winkler, Konstantin Löser, Julia Grander, Madlen Hotze, Sönke Harder, Annika Döding, Martina Meßner, Fabiana Troisi, Maximilian Ardelt, Hartmut Schlüter, Johanna Pachmayr, Óscar Gutiérrez-Gutiérrez, Karl Lenhard Rudolph, Kathrin Thedieck, Ulrike Schulze-Späte, Cristina González-Estévez, Christian Kosan, Aleš Svatoš, Marcel Kwiatkowski, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Fatty acid unsaturation by stearoyl-CoA desaturase 1 (SCD1) protects against cellular stress through unclear mechanisms. Here the authors show 1,2-dioleoyl-sn-glycero-3-phospho-(1’-myo-inositol) is an SCD1-derived signaling lipid that regulates str
Externí odkaz:
https://doaj.org/article/8fff1ccb32314909871bbf27bc179a32
Autor:
Franz Salm, Eva B. Znalesniak, Aikaterini Laskou, Sönke Harder, Hartmut Schlüter, Werner Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12684 (2023)
Tff1 is a typical gastric peptide secreted together with the mucin, Muc5ac. Tff1-deficient (Tff1KO) mice are well known for their prominent gastric phenotype and represent a recognized model for antral tumorigenesis. Notably, intestinal abnormalities
Externí odkaz:
https://doaj.org/article/dba705b437c44edfbf1ead26715a3b06
Autor:
Eva B. Znalesniak, Aikaterini Laskou, Franz Salm, Katharina Haupenthal, Sönke Harder, Hartmut Schlüter, Werner Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7059 (2023)
The lectin TFF2 belongs to the trefoil factor family (TFF). This polypeptide is typically co-secreted with the mucin MUC6 from gastric mucous neck cells, antral gland cells, and duodenal Brunner glands. Here, TFF2 fulfills a protective function by fo
Externí odkaz:
https://doaj.org/article/832643fc0ed541d9b8d19037a19aafbe
Autor:
Fatemeh Hassani Nia, Daniel Woike, Victoria Martens, Malte Klüssendorf, Hans-Hinrich Hönck, Sönke Harder, Hans-Jürgen Kreienkamp
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Background Neurodevelopmental disorders such as autism spectrum disorder (ASD) may be caused by alterations in genes encoding proteins that are involved in synapse formation and function. This includes scaffold proteins such as Shank3, and s
Externí odkaz:
https://doaj.org/article/97bef13100c9431198e38c3473b6b65f
Autor:
Jens Weste, Till Houben, Sönke Harder, Hartmut Schlüter, Eva Lücke, Jens Schreiber, Werner Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15359 (2022)
The polypeptide TFF3 belongs to the trefoil factor family (TFF) of lectins. TFF3 is typically secreted from mucous epithelia together with mucins. Both intestinal and salivary TFF3 mainly exist as disulfide-linked heterodimers with IgG Fc binding pro
Externí odkaz:
https://doaj.org/article/f0aa8b1793aa418f9ef102f912b84468
Autor:
Sophie C. Brandt, Bernhard Ellinger, Thuat van Nguyen, Sönke Harder, Hartmut Schlüter, Richard L. Hahnke, Martin Rühl, Wilhelm Schäfer, Martin Gand
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
A prerequisite for the transition toward a biobased economy is the identification and development of efficient enzymes for the usage of renewable resources as raw material. Therefore, different xylanolytic enzymes are important for efficient enzymati
Externí odkaz:
https://doaj.org/article/846e1733415a4b10aef61cc9613ab320
Autor:
Gerrit Wolters-Eisfeld, Baris Mercanoglu, Bianca T. Hofmann, Thomas Wolpers, Claudia Schnabel, Sönke Harder, Pascal Steffen, Kai Bachmann, Babett Steglich, Jörg Schrader, Nicola Gagliani, Hartmut Schlüter, Cenap Güngör, Jakob R. Izbicki, Christoph Wagener, Maximilian Bockhorn
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 10, Pp 1-13 (2018)
Pancreatic disorders: when protein modification misfires Reduced levels of a protein called Cosmc in the pancreas may lead to pancreatic disorders and a rare form of diabetes. Disruption to glycosylation, the process by which carbohydrates are added
Externí odkaz:
https://doaj.org/article/e4cd471544554380848bc885224144b7
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8872 (2020)
Flooding induces low-oxygen environments (hypoxia or anoxia) that lead to energy disruption and an imbalance of reactive oxygen species (ROS) production and scavenging enzymes in plants. The influence of hypoxia on roots of hydroponically grown maize
Externí odkaz:
https://doaj.org/article/13bcdb06a2b04514907bbdc041d380cb