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In vivo mallard experiments indicate that zanamivir has less potential for environmental influenza A virus resistance development than oseltamivir.

Autor: Nykvist M; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Gillman A; Section for Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Söderström Lindström H; Department of Chemistry, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden., Tang C; Department of Chemistry, Umeå University, Umeå, Sweden., Fedorova G; University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Vodnany, Czech Republic., Lundkvist Å; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Latorre-Margalef N; Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Faculty of Health and Life Sciences, Linnaeus University, Kalmar, Sweden., Wille M; Zoonosis Science Center, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Present address: WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Järhult JD; Section for Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Publikováno v: The Journal of general virology [J Gen Virol] 2017 Dec; Vol. 98 (12), pp. 2937-2949.