Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sílvia Vale-Costa"'
Autor:
Sílvia Vale-Costa, Temitope Akhigbe Etibor, Daniela Brás, Ana Laura Sousa, Mariana Ferreira, Gabriel G Martins, Victor Hugo Mello, Maria João Amorim
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002290 (2023)
It is now established that many viruses that threaten public health establish condensates via phase transitions to complete their lifecycles, and knowledge on such processes may offer new strategies for antiviral therapy. In the case of influenza A v
Externí odkaz:
https://doaj.org/article/30fef2fdbff74e1ebed2f18c41744806
Autor:
Temitope Akhigbe Etibor, Aidan O’Riain, Marta Alenquer, Christian Diwo, Sílvia Vale-Costa, Maria João Amorim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15253 (2023)
Biomolecular condensates are crucial compartments within cells, relying on their material properties for function. They form and persist through weak, transient interactions, often undetectable by classical biochemical approaches. Hence, microscopy-b
Externí odkaz:
https://doaj.org/article/3aa0ec50ffb640e4bb0c76e37736430e
Autor:
Marta Alenquer, Tiago Milheiro Silva, Onome Akpogheneta, Filipe Ferreira, Sílvia Vale-Costa, Mónica Medina-Lopes, Frederico Batista, Ana Margarida Garcia, Vasco M. Barreto, Cathy Paulino, João Costa, João Sobral, Maria Diniz-da-Costa, Susana Ladeiro, Rita Corte-Real, José Delgado Alves, Ricardo B. Leite, Jocelyne Demengeot, Maria João Rocha Brito, Maria João Amorim
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Background Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given the ongoing appearance of SARS-CoV-2 variants. Children remain largely unvaccinated and are susceptible to infe
Externí odkaz:
https://doaj.org/article/90766476328c4808b91b52d1807d82f0
Autor:
Marta Alenquer, Sílvia Vale-Costa, Temitope Akhigbe Etibor, Filipe Ferreira, Ana Laura Sousa, Maria João Amorim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Influenza A virus forms cytosolic inclusions containing viral ribonucleoproteins. Here, the authors show that viral inclusions form juxtaposed the endoplasmic reticulum and have liquid properties, likely constituting sites of assembly of epidemic and
Externí odkaz:
https://doaj.org/article/94d834963d7a4427afe59405bbcf676a
Autor:
Filipe Marques, Sílvia Vale-Costa, Tânia Cruz, Joana Moreira Marques, Tânia Silva, João Vilares Neves, Sofia Cortes, Ana Fernandes, Eduardo Rocha, Rui Appelberg, Pedro Rodrigues, Ana M. Tomás, Maria Salomé Gomes
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-12 (2015)
Abstract Background Visceral leishmaniasis is a severe and potentially fatal disease caused by protozoa of the genus Leishmania, transmitted by phlebotomine sandflies. In Europe and the Mediterranean region, L. infantum is the commonest agent of visc
Externí odkaz:
https://doaj.org/article/dca6a0bfb58c45f5949929d36e8dafdf
Autor:
Sílvia Vale-Costa, Sandra Gomes-Pereira, Carlos Miguel Teixeira, Gustavo Rosa, Pedro Nuno Rodrigues, Ana Tomás, Rui Appelberg, Maria Salomé Gomes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 2, p e2061 (2013)
Iron plays a central role in host-parasite interactions, since both intervenients need iron for survival and growth, but are sensitive to iron-mediated toxicity. The host's iron overload is often associated with susceptibility to infection. However,
Externí odkaz:
https://doaj.org/article/b919dd1cb3764a2f97a61b02ba68eb44
Autor:
Sílvia Vale-Costa, Maria João Amorim
Publikováno v:
Viruses, Vol 8, Iss 3, p 64 (2016)
Many viruses exploit specific arms of the endomembrane system. The unique composition of each arm prompts the development of remarkably specific interactions between viruses and sub-organelles. This review focuses on the viral–host interactions occ
Externí odkaz:
https://doaj.org/article/98c56e19ac004590b3f2428b641c85b7
Autor:
Temitope Akhigbe Etibor, Sílvia Vale-Costa, Sindhuja Sridharan, Daniela Brás, Isabelle Becher, Victor Hugo Mello, Filipe Ferreira, Marta Alenquer, Mikhail M Savitski, Maria João Amorim
Controlled phase transitions in biomolecular condensates will provide further understanding to cell physiology and diseases as the material properties in these structures are tailored for function. Since native or engineered transitions affect conden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e56309c6cd0aa0e3e6d01c795a4356f
Autor:
Temitope Akhigbe Etibor, Sílvia Vale-Costa, Sindhuja Sridharan, Daniela Brás, Isabelle Becher, Victor Hugo Mello, Filipe Ferreira, Marta Alenquer, Mikhail M Savitski, Maria João Amorim
Publikováno v:
bioRxiv
SummaryMultiple viral infections form biomolecular condensates in the host cell to compartmentalize viral reactions. Accumulating evidence indicates that these viral condensates may be hardened, a strategy with potential for exploitation as novel ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa78e08879d984bd0ce5490a5fb4928b
https://doi.org/10.1101/2022.08.03.502602
https://doi.org/10.1101/2022.08.03.502602
Autor:
Daniel Lévy, Feng-Ching Tsai, Daniel Hamaoui, Sílvia Vale-Costa, Maria João Amorim, Aurélie Di Cicco, Yueyao Zhu, Anne-Sophie Macé, Tal Keren-Kaplan, Mathilde Dimarco, Cédric Delevoye, Patricia Bassereau, Ilse Hurbain, Juan S. Bonifacino, Michael S. Marks, Agathe Subtil, Riddhi Atul Jani, Graça Raposo
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, 2022, 221 (11), pp.e202110132. ⟨10.1083/jcb.202110132⟩
Journal of Cell Biology, 2022, 221 (11), pp.e202110132. ⟨10.1083/jcb.202110132⟩
International audience; The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233669a4d26091add9612c1976ec4280
https://hal.archives-ouvertes.fr/hal-03452929
https://hal.archives-ouvertes.fr/hal-03452929