Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sílvia Pérez-Lluch"'
Autor:
Carme Arnan, Sebastian Ullrich, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 coupled to a single gRNA has pro
Externí odkaz:
https://doaj.org/article/4c100e2cafc94ba2aca5955791116310
Autor:
Sílvia Pérez-Lluch, Cecilia C Klein, Alessandra Breschi, Marina Ruiz-Romero, Amaya Abad, Emilio Palumbo, Lyazzat Bekish, Carme Arnan, Roderic Guigó
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009245 (2020)
Natural Antisense Transcripts (NATs) are long non-coding RNAs (lncRNAs) that overlap coding genes in the opposite strand. NATs roles have been related to gene regulation through different mechanisms, including post-transcriptional RNA processing. Wit
Externí odkaz:
https://doaj.org/article/0954f744ac7e470b99f830337ebb88c9
Autor:
Ritobrata Ghose, Álvaro Aranguren-Ibáñez, Niccolò Arecco, Diego Balboa, Marc Bataller, Sergi Beltran, Hannah Benisty, Angèle Bénard, Edgar Bernardo, Sílvia Carbonell Sala, Eloi Casals, Ludovica Ciampi, Livia Condemi, Alberto Corvó, Marta Cosín-Tomás, Mirabai Cuenca-Ardura, Juan Manuel Duran Serrano, María Isabel Espejo Díaz, Marcos Fernandez Callejo, Antoni Gañez-Zapater, Raquel Garcia-Castellanos, Romina Garrido, Gil Henkin, Toni Hermoso Pulido, Xavier Hernandez-Alias, Jorge Herrero Vicente, Matthew Ingham, Wei Ming Lim, Sílvia Llonch, Elena Marmesat Bertoli, Irene Miguel-Escalada, Ariadna Montero-Blay, Cristina Navarrete Hernández, Maria Victoria Neguembor, Róisín-Ana Ní Chárthaigh, Natalia Pardo-Lorente, Laura Pascual-Reguant, Sílvia Pérez-Lluch, Reyes Perza, Martina Pesaresi, Daniel Picó Amador, Paula Pifarré, Davide Piscia, Marcos Plana-Carmona, Julia Ponomarenko, Leandro Radusky, Ezequiel Rivero, Malgorzata Rogalska, Guillem Torcal Garcia, José Wojnacki
Publikováno v:
F1000Research, Vol 9 (2020)
The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a vaccine, as well as to contribute to mass testing, which
Externí odkaz:
https://doaj.org/article/a31f23efbb70401e91a65643d3267f89
Autor:
Marina Ruiz-Romero, Cecilia C. Klein, Sílvia Pérez-Lluch, Amaya Abad, Alessandra Breschi, Roderic Guigó
BackgroundDuring development, most cells undergo striking changes in order to develop into functional tissues. All along this process, the identity of each tissue arises from the particular combination of regulatory transcription factors that specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bf1eddc5df54c146d8ebe15892936f0
https://doi.org/10.1101/2022.04.22.489139
https://doi.org/10.1101/2022.04.22.489139
Autor:
Ramil Nurtdinov, María Sanz, Amaya Abad, Alexandre Esteban, Sebastian Ullrich, Carme Arnan, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó
Many developmental and differentiation processes take substantially longer in human than in mouse. To investigate the molecular mechanisms underlying this phenomenon, here we have specifically focused on the transdifferentiation from B cells to macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::653419c0fee28826c03129aa222bea5d
https://doi.org/10.1101/2021.10.28.466072
https://doi.org/10.1101/2021.10.28.466072
Autor:
Roderic Guigó, Alexandre Esteban, Carlos Pulido-Quetglas, Carme Arnan, Joan Blanco-Fernandez, Sebastian Ullrich, Sílvia Pérez-Lluch, Estel Aparicio-Prat, Rory Johnson, Ramil N. Nurtdinov
Publikováno v:
Arnan, Carme; Ullrich, Sebastian; Pulido-Quetglas, Carlos; Nurtdinov, Ramil; Esteban, Alexandre; Blanco-Fernandez, Joan; Aparicio-Prat, Estel; Johnson, Rory; Pérez-Lluch, Sílvia; Guigó, Roderic (2022). Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages. BMC Genomics, 23(1), p. 402. BioMed Central 10.1186/s12864-022-08612-7
CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 coupled to a single gRNA has proven to ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fced87456a3125c78ee1e7f405bf774
https://pubmed.ncbi.nlm.nih.gov/35619054
https://pubmed.ncbi.nlm.nih.gov/35619054
Autor:
Pablo Villegas-Mirón, Roderic Guigó, Jaume Bertranpetit, Sandra Acosta, Hafid Laayouni, Alba Segarra-Casas, Sílvia Pérez-Lluch, Isabel Turpin, Beatrice Borsari
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Genome Res
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Genome Res
Digital.CSIC. Repositorio Institucional del CSIC
instname
Tissue function and homeostasis reflect the gene expression signature by which the combination of ubiquitous and tissue-specific genes contribute to the tissue maintenance and stimuli-responsive function. Enhancers are central to control this tissue-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604ad8b89073d59a64391fcdac2480f7
http://hdl.handle.net/2445/195705
http://hdl.handle.net/2445/195705
Autor:
Roderic Guigó, Alessandra Breschi, Lyazzat Bekish, Sílvia Pérez-Lluch, Emilio Palumbo, Carme Arnan, Amaya Abad, Cecilia C. Klein, Marina Ruiz-Romero
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009245 (2020)
PLoS Genetics
PLoS Genetics
Natural Antisense Transcripts (NATs) are long non-coding RNAs (lncRNAs) that overlap coding genes in the opposite strand. NATs roles have been related to gene regulation through different mechanisms, including post-transcriptional RNA processing. Wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95c6df2138e7c481bae0da9b542165b
https://doaj.org/article/0954f744ac7e470b99f830337ebb88c9
https://doaj.org/article/0954f744ac7e470b99f830337ebb88c9
Autor:
Emilio Palumbo, Roderic Guigó, Amaya Abad, Sanz M, Beatrice Borsari, Sílvia Pérez-Lluch, Bruna R. Correa, Cecilia C. Klein, Esteban A, Ramil N. Nurtdinov, Marina Ruiz-Romero, Rory Johnson
SummaryWe have monitored the transcriptomic and epigenomic status of cells at twelve time-points during the transdifferentiation of human pre-B cells into macrophages. Using this data, we have investigated some fundamental questions regarding the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e19431b41a0aabda06bf1a82d9f538cd
https://doi.org/10.1101/2020.11.20.391524
https://doi.org/10.1101/2020.11.20.391524
Autor:
Rory Johnson, Thomas R. Gingeras, Carrie A. Davis, Sílvia Pérez-Lluch, Adam Frankish, Silvia Carbonell, Roderic Guigó, Julien Lagarde, Amaya Abad, Barbara Uszczynska-Ratajczak, Jennifer Harrow
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature genetics
instname
Nature genetics
Accurate annotations of genes and their transcripts is a foundation of genomics, but no annotation technique presently combines throughput and accuracy. As a result, reference gene collections remain incomplete: many gene models are fragmentary, whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e1cd977e798406e9c5dd31f063adff
https://doi.org/10.1038/ng.3988
https://doi.org/10.1038/ng.3988