Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sílvia Menéndez"'
Autor:
Clara Montagut, Ana Rovira, Joan Albanell, Beatriz Bellosillo, Michael Kragh, Thomas Tuxen Poulsen, Mariona Gelabert-Baldrich, Sergi Clavé, Alba Dalmases, Élisabeth Gaye, Sílvia Menéndez, Mar Iglesias, Laura Visa, Oriol Arpí, Francisco Javier Sánchez-Martín, Aïda Sampera
Supplementary Figures and Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c283e805f3486b9bc952a2ff90fadb7
https://doi.org/10.1158/1535-7163.22518999.v1
https://doi.org/10.1158/1535-7163.22518999.v1
Autor:
Clara Montagut, Ana Rovira, Joan Albanell, Beatriz Bellosillo, Michael Kragh, Thomas Tuxen Poulsen, Mariona Gelabert-Baldrich, Sergi Clavé, Alba Dalmases, Élisabeth Gaye, Sílvia Menéndez, Mar Iglesias, Laura Visa, Oriol Arpí, Francisco Javier Sánchez-Martín, Aïda Sampera
Despite the clinical benefit of trastuzumab, eventually all HER2-amplified gastric cancer tumors develop drug resistance. We aimed to identify molecular mechanisms of acquired resistance to trastuzumab in gastric cancer by using well-established cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5486c13f06d3e5057276e0a3643c9c
https://doi.org/10.1158/1535-7163.c.6542220
https://doi.org/10.1158/1535-7163.c.6542220
Autor:
Joan Albanell, Miguel López-Botet, Ana Rovira, Abel Gonzalez-Perez, Ana Lluch, Ivonne Vazquez, Sílvia Menéndez, María Martínez-Garcia, Marcel Costa-García, David Tamborero, Mariona Cabo, Carlota Rubio-Perez, Sonia Servitja, Federico Rojo, Aura Muntasell
Supplementary Figure 1: HER2-positive Breast Cancer Study cohorts Supplementary Figure 2: TI-NK cells as categorical variable predicted pCR to anti-HER2 mAb-based neoadjuvant treatment with high sensitivity and specificity Supplementary Table I: TIL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e346b4bb639e2fece1fdea361b35276
https://doi.org/10.1158/1078-0432.22472022.v1
https://doi.org/10.1158/1078-0432.22472022.v1
Autor:
Joan Albanell, Miguel López-Botet, Ana Rovira, Abel Gonzalez-Perez, Ana Lluch, Ivonne Vazquez, Sílvia Menéndez, María Martínez-Garcia, Marcel Costa-García, David Tamborero, Mariona Cabo, Carlota Rubio-Perez, Sonia Servitja, Federico Rojo, Aura Muntasell
Purpose:We investigated the value of tumor-infiltrating NK (TI-NK) cells and HLA class I tumor expression as biomarkers of response to neoadjuvant anti-HER2 antibody–based treatment in breast cancer.Experimental Design:TI-NK cells and HLA-I were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66838d95de12266386b540dae3e8ecb9
https://doi.org/10.1158/1078-0432.c.6528087.v1
https://doi.org/10.1158/1078-0432.c.6528087.v1
Autor:
Sara Santana-Hernández, Jesús Suarez-Olmos, Sonia Servitja, Pau Berenguer-Molins, Marcel Costa-Garcia, Laura Comerma, Anna Rea, Julia Perera-Bel, Silvia Menendez, Oriol Arpí, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo, Iñaki Comino-Méndez, Javier Pascual, Emilio Alba, Miguel López-Botet, Federico Rojo, Ana Rovira, Joan Albanell, Aura Muntasell
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The variability in responses to neoadjuvant treatment with anti-HER2 antibodies prompts to personalized clinical management and the development of innovative treatment strategies. Tumor-infiltrating Natural Killer (TI-NK) cells ca
Externí odkaz:
https://doaj.org/article/5bc22c2f73dc42618cc14ecab70aa357
Autor:
Aura, Muntasell, Federico, Rojo, Sonia, Servitja, Carlota, Rubio-Perez, Mariona, Cabo, David, Tamborero, Marcel, Costa-García, María, Martínez-Garcia, Sílvia, Menéndez, Ivonne, Vazquez, Ana, Lluch, Abel, Gonzalez-Perez, Ana, Rovira, Miguel, López-Botet, Joan, Albanell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(5)
We investigated the value of tumor-infiltrating NK (TI-NK) cells and HLA class I tumor expression as biomarkers of response to neoadjuvant anti-HER2 antibody-based treatment in breast cancer.TI-NK cells and HLA-I were determined by IHC in pretreatmen
Autor:
Laura S Danielson, Maria V Guijarro, Silvia Menendez, Brett Higgins, Qiang Sun, Khushbakhat Mittal, Dorota A Popiolek, Michael Overholtzer, Glyn D Palmer, Eva Hernando
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0278844 (2023)
Leiomyosarcoma (LMS) is an aggressive, often poorly differentiated cancer of the smooth muscle (SM) lineage for which the molecular drivers of transformation and progression are poorly understood. In microRNA (miRNA) profiling studies, miR-130b was p
Externí odkaz:
https://doaj.org/article/811f590e1ad94d7687d8c31f9fb8336d
Autor:
Dalia Raïch-Regué, Javier Gimeno, Laura Llinàs-Mallol, Silvia Menéndez, David Benito, Dolores Redondo, M. José Pérez-Sáez, Marta Riera, Elaine F. Reed, Julio Pascual, Marta Crespo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Antibody-mediated rejection (ABMR) caused by donor-specific HLA-antibodies (DSA) is a mediator of allograft loss after kidney transplantation (KT). DSA can activate microvascular endothelium damage through the mTOR pathway. In this study we assessed
Externí odkaz:
https://doaj.org/article/2d070eb4b9eb4425bc691ec70c7975e1
Autor:
Neus Martínez-Bosch, Noelia Vilariño, Francesc Alameda, Sergi Mojal, Montserrat Arumí-Uria, Cristina Carrato, Iban Aldecoa, Teresa Ribalta, Noemí Vidal, Beatriz Bellosillo, Silvia Menéndez, Sonia Del Barco, Oscar Gallego, Estela Pineda, Raquel López-Martos, Ainhoa Hernández, Carlos Mesia, Anna Esteve-Codina, Nuria de la Iglesia, Carme Balañá, María Martínez-García, Pilar Navarro
Publikováno v:
Cells, Vol 12, Iss 6, p 843 (2023)
Glioblastoma (GBM) is the most frequent primary malignant brain tumor and has a dismal prognosis. Unfortunately, despite the recent revolution of immune checkpoint inhibitors in many solid tumors, these have not shown a benefit in overall survival in
Externí odkaz:
https://doaj.org/article/fe87b94e5dbf4348afbbf8e60ee01f36
Autor:
Erika López-Arribillaga, Bing Yan, Teresa Lobo-Jarne, Yolanda Guillén, Silvia Menéndez, Montserrat Andreu, Anna Bigas, Mar Iglesias, Lluís Espinosa
Publikováno v:
Cells, Vol 10, Iss 11, p 2928 (2021)
Background: Previous studies in mice indicated that Paneth cells and c-Kit-positive goblet cells represent the stem cell niche of the small intestine and colon, respectively, partly by supporting Wnt and Notch activation. Whether these cell populatio
Externí odkaz:
https://doaj.org/article/a2b2abc47bf94a33859ea7afe20bbba6