Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sílvia M. M. A. Pereira-Lima"'
Autor:
Ana R. M. Ribeiro, Catarina S. Miranda, Ana Francisca G. Silva, Filipa D. P. Mendes, Beatriz M. Silva, Bruna A. S. Oliveira, Eduardo D. Paiva, Sónia P. Gonçalves, Sílvia M. M. A. Pereira-Lima, Susana P. G. Costa, Helena P. Felgueiras
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 911 (2024)
In diabetic ulcers, an increased secretion of human neutrophil elastase (HNE) and bacterial infections play crucial roles in hindering healing. Considering that, the present study proposed the development of multi-action polycaprolactone (PCL)/polyet
Externí odkaz:
https://doaj.org/article/1fb58956a94648cb81467410e3e42abd
Autor:
Catarina S. Miranda, Ana Francisca G. Silva, Sílvia M. M. A. Pereira-Lima, Susana P. G. Costa, Natália C. Homem, Helena P. Felgueiras
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 164 (2022)
Electrospinning and wet-spinning have been recognized as two of the most efficient and promising techniques for producing polymeric fibrous constructs for a wide range of applications, including optics, electronics, food industry and biomedical appli
Externí odkaz:
https://doaj.org/article/4adc47d1e9a047dc88c0da8138481575
Autor:
Renata da S Arruda, Sílvia M. M. A. Pereira Lima, Rafaelle Fazzi Gomes, Aline Oliveira da Silva, Isabelle Caroline Bailosa do Rosário
Publikováno v:
Enciclopédia Biosfera. 16:596-604
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
To tackle one of the biggest global health problems, the resistance of microorganisms to antibiotics, a collective effort in the search for more effective agents against bacteria was required. Peptides with antimicrobial activity have been raising mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca7df951ae2649d300c7f3a6a60578c
Autor:
Susana P. G. Costa, A. Francisca G. Silva, Helena P. Felgueiras, Sílvia M. M. A. Pereira Lima
Publikováno v:
Proceedings of 6th International Electronic Conference on Medicinal Chemistry.
Autor:
Susana P. G. Costa, Elisabete M. S. Castanheira, Rui D. V. Fernandes, Carina Martins Carvalho, Sílvia M. M. A. Pereira-Lima, Vânia I. B. Castro
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Analogues of Peptaibolin, a peptaibol with antibiotic activity, incorporating α,α-dialkylglycines (Deg, Dpg, and Ac6c) at selected positions were synthesised by MW-SPPS and fully characterized. A control analogue incorporating L-alanine was also pr
Publikováno v:
Current Chemical Biology. 8:109-113
Foundation for Science and Technology (FCT) – Portugal and Fundo Europeu de Desenvolvimento Regional (FEDER) for financial support to Chemistry Centre of University of Minho. The NMR spectrometer Bruker Avance II+ 400 is part of the National NMR Ne
Publikováno v:
ARKIVOC, Vol 2014, Iss 5, Pp 170-180 (2014)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The application of trialkyloxonium tetrafluoroborates for N-alkylation of the nonnatural amino acid Cα, α-dimethylglycine is described. Several methyl esters of dimethylglycine protected with different amine protecting groups were subject to N-ethy
Autor:
Filipa C.S.C. Pinto, Lídia M. P. C. Albuquerque, Sílvia M. M. A. Pereira-Lima, Hernâni L. S. Maia, Raquel Gonçalves-Maia, Cristina Ventura
Publikováno v:
Tetrahedron. 62:8184-8198
Several derivatives of N-phenylacetyl-N-benzyl-α,α-dimethylglycine cyclohexylamide and their α,α-dibenzylglycine analogues were synthesised by a Ugi–Passerini reaction. In addition, a few analogues of the former but having an N-phenyl instead o
Publikováno v:
Organic & Biomolecular Chemistry. 1:1475-1479
A general and simple strategy for routine peptide synthesis with α,α-dialkyl glycines taking advantage of the four-component Ugi–Passerini reaction is presented. The isonitrile required for the reaction can be relatively simple and its selection