Výsledky vyhledávání - "Sílvia E. Matsuo"

TGFbeta, activin and SMAD signalling in thyroid cancer

Autor: Julio C. Ricarte-Filho, Edna Teruko Kimura, Sílvia E. Matsuo

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia, Volume: 51, Issue: 5, Pages: 683-689, Published: JUL 2007
Arquivos Brasileiros de Endocrinologia & Metabologia v.51 n.5 2007
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM

TGFbeta e activina são membros da superfamília TGFbeta e desempenham um amplo papel no desenvolvimento, proliferação e apoptose. Estes fatores de crescimento exercem seus efeitos biológicos ligando-se a receptores de membrana do tipo I e do tipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfc3f9204484b35f5744034993d8db7
https://doi.org/10.1590/s0004-27302007000500005

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Marcadores biológicos de tumores tiroidianos

Autor: Kátia N. Ebina, S. G. Leoni, Sílvia E. Matsuo, Luciane Martins, Julio C. Ricarte-Filho, Edna Teruko Kimura, Denise Hajjar

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia. 48:114-125

Um marcador biológico ideal deve ser específico e sensível para identificar o tipo tumoral e caracterizar o estágio da progressão neoplásica. Os tumores de tiróide originam-se de dois tipos celulares: 1) carcinoma medular originário de célul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6b1cba68c491c71f2ab23f02bd1e010
https://doi.org/10.1590/s0004-27302004000100013

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Expression of SMAD proteins, TGF-beta/activin signaling mediators, in human thyroid tissues

Autor: Edna Teruko Kimura, Simone M. Siguematu, Kátia N. Ebina, Maria C. Ferro, Celso U. M. Friguglietti, Marco Aurélio Vamondes Kulcsar, Sílvia E. Matsuo, Ana Paula Zen Petisco Fiore

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia v.54 n.4 2010
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
ResearcherID

OBJECTIVE: To investigate the expression of SMAD proteins in human thyroid tissues since the inactivation of TGF-β/activin signaling components is reported in several types of cancer. Phosphorylated SMAD 2 and SMAD3 (pSMAD2/3) associated with the SM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7a12f147f13a9617b3276e7a875e41
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302010000400010

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[TGFbeta, activin and SMAD signalling in thyroid cancer]

Autor: Edna T, Kimura, Sílvia E, Matsuo, Júlio Cézar, Ricarte-Filho

Publikováno v: Arquivos brasileiros de endocrinologia e metabologia. 51(5)

TGFbeta and activin are members of the TGFbeta superfamily and play a wide role in development, proliferation and apoptosis. These growth factors exert their biological effects by binding to the type I and II membrane receptors to transduce their sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3aae3f16fe23d43189e4408cee05034
https://pubmed.ncbi.nlm.nih.gov/17891231

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Transforming growth factor-beta1 and activin A generate antiproliferative signaling in thyroid cancer cells

Autor: Edna Teruko Kimura, Alison Colquhoun, Sílvia E. Matsuo, S. G. Leoni

Publikováno v: The Journal of endocrinology. 190(1)

Transforming growth factor-beta 1 (TGF-β1) and activin A (ActA) induce similar intracellular signaling mediated by the mothers against decapentaplegic homolog (SMAD) proteins. TGF-β1 is a potent antimitogenic factor for thyroid follicular cells, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02d9463713425df4a4892ceb9cc149d
https://pubmed.ncbi.nlm.nih.gov/16837618

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Expression of Smad4 and Smad7 in human thyroid follicular carcinoma cell lines

Autor: Edna Teruko Kimura, Kátia N. Ebina, Janete M. Cerutti, Sílvia E. Matsuo, Rui M. B. Maciel, Luciane Martins

Publikováno v: Journal of endocrinological investigation. 26(6)

Smad proteins have been shown tomediate the signal transduction pathway downstream of the transforming growth factor beta (TGFbeta). TGFbeta induces the phosphorylation of Smad2 and Smad3 which associate with Smad4 and translocate to the nucleus wher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7721b5594ea4f10990848c9910398a
https://pubmed.ncbi.nlm.nih.gov/12952364

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Galectin-3 messenger ribonucleic acid and protein are expressed in benign thyroid tumors

Autor: Kátia N. Ebina, Luciane Martins, Sílvia E. Matsuo, Edna Teruko Kimura, Celso U. M. Friguglietti, Marco Aurélio Vamondes Kulcsar

Publikováno v: The Journal of clinical endocrinology and metabolism. 87(10)

Galectin-3 is a protein of the lectin family that has been associated with neoplastic processes in various tissues. In the thyroid, expression of this protein has been described in differentiated follicular cancer, suggesting that the immunohistochem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cb09f3b97982c5d66081976cc0d870
https://pubmed.ncbi.nlm.nih.gov/12364477

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