Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Séverine Roselli"'
Autor:
Nikita Panicker, Melody Coutman, Charley Lawlor-O’Neill, Richard G. S. Kahl, Séverine Roselli, Nicole M. Verrills
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The serine/threonine protein phosphatase 2A (PP2A) is a master regulator of the complex cellular signaling that occurs during all stages of mammalian development. PP2A is composed of a catalytic, a structural, and regulatory subunit, for which there
Externí odkaz:
https://doaj.org/article/079b63daaa234f27927c5204d2bd7850
Autor:
Hubert Hondermarck, Marjorie M. Walker, John Attia, Séverine Roselli, Nathan Griffin, Mark Marsland, Christopher Oldmeadow, Sam Faulkner
Publikováno v:
Biomolecules, Vol 10, Iss 1329, p 1329 (2020)
Biomolecules
Volume 10
Issue 9
Biomolecules
Volume 10
Issue 9
The tyrosine kinase receptor A (NTRK1/TrkA) is increasingly regarded as a therapeutic target in oncology. In breast cancer, TrkA contributes to metastasis but the clinicopathological significance remains unclear. In this study, TrkA expression was as
Autor:
Christopher J. Scarlett, Séverine Roselli, Joshua S. Brzozowski, Richard G. S. Kahl, Helen Jankowski, Leonie K. Ashman, Judith Weidenhofer, Danielle R. Bond, William J. Muller, Mamta Pariyar, Claude Boucheix, Murray J. Cairns, Kelly A. Avery-Kiejda, Crystal Naudin
Publikováno v:
Cancers
Volume 12
Issue 4
Cancers, Vol 12, Iss 4, p 795 (2020)
Volume 12
Issue 4
Cancers, Vol 12, Iss 4, p 795 (2020)
Breast cancer is the most commonly diagnosed and the second leading cause of cancer-related mortality among women worldwide. miR-518f-5p has been shown to modulate the expression of the metastasis suppressor CD9 in prostate cancer. However, the role
Autor:
Sam Faulkner, Rick F. Thorne, Philip Jobling, Hubert Hondermarck, S.M. Rodrigues Oliveira, Séverine Roselli, Xudong Zhang, Christopher W. Rowe, Christopher Oldmeadow, Chen Chen Jiang, John Attia, Marjorie M. Walker
Publikováno v:
The American Journal of Pathology. 188:229-241
Neurotrophin receptors are emerging targets in oncology, but their clinicopathologic significance in thyroid cancer is unclear. In this study, the neurotrophin tyrosine receptor kinase TrkA (also called NTRK1), the common neurotrophin receptor p75 NT
Autor:
Danielle R. Bond, Judith Weidenhofer, Rodney J. Scott, Leonie K. Ashman, Séverine Roselli, Brian J Smith, Matthew D. Dun, Crystal Naudin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
In humans and FVB/N mice, loss of functional tetraspanin CD151 is associated with glomerular disease characterised by early onset proteinuria and ultrastructural thickening and splitting of the glomerular basement membrane (GBM). To gain insight into
Autor:
Ben T. Copeland, Nicole M. Verrills, Richard G. S. Kahl, Abdul Mannan, Nikita Panicker, Matthew D. Dun, Lauren F. Watt, Séverine Roselli, Barbara Young
Publikováno v:
Breast Cancer Research and Treatment. 166:117-131
Protein phosphatase 2A (PP2A) is a family of serine/threonine phosphatases that regulate multiple cellular signalling pathways involved in proliferation, survival and apoptosis. PP2A inhibition occurs in many cancers and is considered a tumour suppre
Autor:
Hubert Hondermarck, Yohann Demont, Séverine Roselli, Marjorie M. Walker, Geneviève Choquet, Philippe Leissner, John Attia, Christopher Oldmeadow, Sam Faulkner, Jay Pundavela
Publikováno v:
Oncotarget
The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to define the clinicopathological significance of proNGF in thyroid cancer. ProNGF expression was
Autor:
Phillip Jobling, Sónia M R Oliveira, Hubert Hondermarck, Jay Pundavela, Marjorie M. Walker, Séverine Roselli
Publikováno v:
Cancer Research. 75:1777-1781
Recent studies have revealed the essential role played by nerves in tumor progression. Nerves have been shown to infiltrate the tumor microenvironment and actively stimulate cancer cell growth and dissemination. This mechanism involves the release of
Autor:
Crystal, Naudin, Brian, Smith, Danielle R, Bond, Matthew D, Dun, Rodney J, Scott, Leonie K, Ashman, Judith, Weidenhofer, Séverine, Roselli
Publikováno v:
Scientific Reports
In humans and FVB/N mice, loss of functional tetraspanin CD151 is associated with glomerular disease characterised by early onset proteinuria and ultrastructural thickening and splitting of the glomerular basement membrane (GBM). To gain insight into
Autor:
Joshua S. Brzozowski, Kathryn A. Skelding, Judith Weidenhofer, Séverine Roselli, Danielle R. Bond
Publikováno v:
Breast Cancer Management. 3:123-126
123 ISSN 1758-1923 10.2217/BMT.14.2 © 2014 Future Medicine Ltd Breast Cancer Manage. (2014) 3(2), 123–126 Advances in the treatment of breast cancer have slowed in recent years, with approximately 41,000 women/per year in the USA alone succumbing