Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Séverine Péchiné"'
Autor:
Lise Hunault, Emile Auria, Patrick England, Julien Deschamps, Romain Briandet, Vanessa Kremer, Bruno Iannascoli, Léo Vidal-Maison, Chunguang Guo, Lynn Macdonald, Séverine Péchiné, Cécile Denève-Larrazet, Bruno Dupuy, Guy Gorochov, Pierre Bruhns, Delphine Sterlin
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTClostridioides difficile (C. difficile), a gram-positive anaerobic and spore-forming bacterium, is the leading cause of nosocomial antibiotic-associated diarrhea in adults which is characterized by high levels of recurrence and mortality. Sur
Externí odkaz:
https://doaj.org/article/fd64b7a0f8ab4b62930cc098c58b38b3
Autor:
Tri-Hanh-Dung Doan, Marie-Françoise Bernet-Camard, Sandra Hoÿs, Claire Janoir, Séverine Péchiné
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 624 (2022)
Clostridioides difficile infection (CDI) is the primary cause of health-care-associated infectious diarrhea. Treatment requires mostly specific antibiotics such as metronidazole (MTZ), vancomycin or fidaxomicin. However, approximately 20% of treated
Externí odkaz:
https://doaj.org/article/ae494ad29b0545eb85f50eed7bd0361f
Autor:
Tri-Hanh-Dung Doan, Stéphanie Yen-Nicolaÿ, Marie-Françoise Bernet-Camard, Isabelle Martin-Verstraete, Séverine Péchiné
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241903 (2020)
Clostridioides difficile is responsible for various intestinal symptoms from mild diarrhea to severe pseudomembranous colitis and is the primary cause of antibiotic-associated diarrhea in adults. Metronidazole was the first-line treatment for mild to
Externí odkaz:
https://doaj.org/article/f8e5495ca4754d71abcb590463e0a1cb
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
New therapies are needed to prevent and treat Clostridium difficile infection and to limit the rise in antibiotic resistance. Besides toxins, several surface components have been characterized as colonization factors and have been shown as immunogeni
Externí odkaz:
https://doaj.org/article/68cf8aee2b534428a08dede1dbff20fa
Autor:
Jean-François Bruxelle, Assaf Mizrahi, Sandra Hoÿs, Anne Collignon, Claire Janoir, Séverine Péchiné
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187212 (2017)
The immunogenicity of bacterial flagellin has been reported in different studies. By its close interaction with the immune system, the flagellin represents an interesting adjuvant and vaccine candidate. Salmonella Typhimurium flagellin has already be
Externí odkaz:
https://doaj.org/article/300a1fb783f849f092a45b3c59a7e084
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81112 (2013)
Clostridium difficile is a pathogen which is responsible for diarrhea and colitis, particularly after treatment with antibiotics. Clinical signs are mainly due to two toxins, TcdA and TcdB. However, the first step of pathogenesis is the colonization
Externí odkaz:
https://doaj.org/article/89f6387406e446d4b651ad33ab677afd
Autor:
Nicholas J. Harmer, Andrea Kovacs-Simon, Séverine Péchiné, Claire Janoir, Jean François Bruxelle, William J. Bradshaw, K. Ravi Acharya, Stephen L. Michell
Publikováno v:
The Journal of Biological Chemistry
Clostridioides difficile is the primary cause of antibiotic-associated diarrhea and colitis, a healthcare-associated intestinal disease resulting in a significant fatality rate. Colonization of the gut is critical for C. difficile pathogenesis. The b
Publikováno v:
Anaerobe. 54:164-168
Clostridium difficile is a major cause of healthcare-associated diarrhea. SlpA is the precursor of the S-layer of C. difficile. The aim of this work was to evaluate the humoral immune response of hospitalized patients to SlpA and its potential role o
Autor:
Stéphanie Yen-Nicolaÿ, Marie-Françoise Bernet-Camard, Séverine Péchiné, Isabelle Martin-Verstraete, Tri-Hanh-Dung Doan
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (11), pp.e0241903. ⟨10.1371/journal.pone.0241903⟩
PLoS ONE, 2020, 15 (11), pp.e0241903. ⟨10.1371/journal.pone.0241903⟩
PLoS ONE, Vol 15, Iss 11, p e0241903 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (11), pp.e0241903. ⟨10.1371/journal.pone.0241903⟩
PLoS ONE, 2020, 15 (11), pp.e0241903. ⟨10.1371/journal.pone.0241903⟩
PLoS ONE, Vol 15, Iss 11, p e0241903 (2020)
Clostridioides difficile is responsible for various intestinal symptoms from mild diarrhea to severe pseudomembranous colitis and is the primary cause of antibiotic-associated diarrhea in adults. Metronidazole was the first-line treatment for mild to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36987963a12c993069e9ab2b8cc05ea4
https://hal.inrae.fr/hal-03339710/document
https://hal.inrae.fr/hal-03339710/document
Autor:
Nicolas Tsapis, Claire Janoir, Jean-François Bruxelle, Anne Collignon, Séverine Péchiné, Sandra Hoys, Elias Fattal
Publikováno v:
Vaccine
Vaccine, Elsevier, 2018, 36 (40), pp.6017-6021. ⟨10.1016/j.vaccine.2018.08.013⟩
Vaccine, Elsevier, 2018, 36 (40), pp.6017-6021. ⟨10.1016/j.vaccine.2018.08.013⟩
International audience; Clostridium difficile flagellin FliC is a highly immunogenic pathogen-associated molecular pattern playing a key role in C. difficile pathogenesis and gut colonization. Here, we designed an oral vaccine against C. difficile wi