Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Séverine Hebbe"'
Autor:
Catherine Robin-Jagerschmidt, Helene Jary, Ellen van der Aar, Nicolas Triballeau, Luke Jonathan Alvey, Francois Nique, Denis Guédin, Kris Van Beeck, Dominque Minet, Florence Namour, Jean H.M. Feyen, Pierre Deprez, Hugo Klaassen, Jean-Michel Lefrancois, Roland Blanque, Christophe Peixoto, Murielle Manioc, Séverine Hebbe, Stephen Robert Fletcher, Christopher Gaëtan Housseman
Publikováno v:
Journal of Medicinal Chemistry. 55:8236-8247
Structural modification performed on a 4-methyl-4-(4-hydroxyphenyl)hydantoin series is described which resulted in the development of a new series of 4-(hydroxymethyl)diarylhydantoin analogues as potent, partial agonists of the human androgen recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841982488e4fec11bfd3145a00ecb1c9
https://doi.org/10.1021/jm300281x
https://doi.org/10.1021/jm300281x
Publikováno v:
Helvetica Chimica Acta. 91:2181-2202
The A*[s]U(*) dinucleosides 1 and 2 form thermoreversible gels in organic solvents. The basis of the gelation is the formation of linear aggregates by base pairing following desolvation of the nucleobases. This is evidenced by the absence of gel form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1fdec0a80463595f89c55902b3ac05c
https://doi.org/10.1002/hlca.200890236
https://doi.org/10.1002/hlca.200890236
Autor:
Francois Nique, Denis Guédin, Nicolas Triballeau, Eric Duval, Jean-Michel Lemoullec, Denis Annoot, Catherine Robin-Jagerschmidt, Maxime Thauvin, Jean-Michel Lefrancois, Thierry Prangé, Laurence Michoux, Philippe Clément-Lacroix, Damien Fleury, Pierre Deprez, Patrick Mollat, Séverine Hebbe, Dominique Minet, Christophe Peixoto
Publikováno v:
Journal of medicinal chemistry. 55(19)
A novel selective androgen receptor modulator scaffold has been discovered through structural modifications of hydantoin antiandrogens. Several 4-(4-hydroxyphenyl)-N-arylhydantoins displayed partial agonism with nanomolar in vitro potency in transact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac608008905445d4f9b1a1f2414f5434
https://pubmed.ncbi.nlm.nih.gov/22897611
https://pubmed.ncbi.nlm.nih.gov/22897611
Autor:
Catherine Howsham, Séverine Hebbe, Jean-François Basset, Anthony G. M. Barrett, Thomas Werner, Jan Bräckow, Sarah M. Major, Ismael Navarro
Publikováno v:
Journal of the American Chemical Society. 130(31)
Diketo-1,3-dioxin-2-ones underwent retro-Diels-Alder reaction on heating in toluene at 110 degrees C to generate alpha,gamma,-triketo-ketenes. These were trapped with alcohols to provide 2,4,6-triketocarboxylates, which were smoothly aromatized by se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87596d090de16b8d2443ab444a80d7d7
https://pubmed.ncbi.nlm.nih.gov/18611011
https://pubmed.ncbi.nlm.nih.gov/18611011
Publikováno v:
Helvetica Chimica Acta; Nov2008, Vol. 91 Issue 11, p2181-2202, 22p