Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Séverine Gratia"'
Autor:
Lucia Potenza, Séverine Gratia, Piero Sestili, Valérie Novel-Chaté, Coralie Schnebelen, Uwe Schlattner, Malgorzata Tokarska-Schlattner, Laurence Kay, Amal Seffouh
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2012, epub ahead of print. ⟨10.1093/cvr/cvs134⟩
Scopus-Elsevier
Cardiovascular Research, Oxford University Press (OUP), 2012, epub ahead of print. ⟨10.1093/cvr/cvs134⟩
Scopus-Elsevier
International audience; AIMS: Cardiotoxic side effects of anthracyclines, the most widely used anticancer drugs, are well documented, while mechanisms involved are not fully elucidated. The cellular energy sensor and regulator AMP-activated protein k
Autor:
Rita Guzun, Michael Zaugg, Malgorzata Tokarska-Schlattner, Eliana Lucchinetti, Séverine Gratia, Uwe Schlattner, Laurence Kay, Valdur Saks
Publikováno v:
AJP-Regulatory, Integrative and Comparative Physiology
AJP-Regulatory, Integrative and Comparative Physiology, American Physiological Society, 2010, 298 (4), pp.R1075-88. ⟨10.1152/ajpregu.00360.2009⟩
AJP-Regulatory, Integrative and Comparative Physiology, American Physiological Society, 2010, 298 (4), pp.R1075-88. ⟨10.1152/ajpregu.00360.2009⟩
International audience; Doxorubicin (DXR) belongs to the most efficient anticancer drugs. However, its clinical application is limited by the risk of severe cardiac-specific toxicity, for which an efficient treatment is missing. Underlying molecular