Výsledky vyhledávání - "Séverine Freisz"

Sequence and structure requirements for specific recognition of HIV-1 TAR and DIS RNA by the HIV-1 Vif protein

Autor: Lamine Hafirassou, Christophe Romier, Eric Ennifar, Joelle Mezher, Séverine Freisz, Philippe Dumas, Yves Nominé, Philippe Wolff

Publikováno v: RNA Biology. 9:966-977

The HIV-1 Vif protein plays an essential role in the regulation of the infectivity of HIV-1 virion and in vivo pathogenesis. Vif neutralizes the human DNA-editing enzyme APOBEC3 protein, an antiretroviral cellular factor from the innate immune system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8e70e6d936c4d6129abb83e9cb8f4b
https://doi.org/10.4161/rna.20483

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Crystal structure of HIV-1 reverse transcriptase bound to a non-nucleoside inhibitor with a novel mechanism of action

Autor: Giovanni Maga, Eric Ennifar, Philippe Dumas, Guillaume Bec, Philippe Wolff, Séverine Freisz, Emmanuele Crespan, Marco Radi, Maurizio Botta, Lucilla Angeli

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2010, 49 (10), pp.1805-8. ⟨10.1002/anie.200905651⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3fc2afda146eeb1473b4b387c52bf7
https://hal.archives-ouvertes.fr/hal-00484515

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Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site

Autor: Kathrin Lang, Séverine Freisz, Eric Ennifar, Ronald Micura, Philippe Dumas

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2008, 47 (22), pp.4110-3. ⟨10.1002/anie.200800726⟩
Angewandte Chemie (English Edition)
Angewandte Chemie (English Edition), John Wiley & Sons, 2008, 47 (22), pp.4110-3. ⟨10.1002/anie.200800726⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eb421708614149dd248bb84b30e78b
https://pubmed.ncbi.nlm.nih.gov/18435520

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Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: thermodynamics and effect on the kissing-loop to duplex conversion

Autor: Philippe Dumas, Clarisse Maechling, Séverine Freisz, Bernard Spiess, Eric Ennifar, Roland Marquet, Serena Bernacchi

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2007, 35 (21), pp.7128-39. ⟨10.1093/nar/gkm856⟩

International audience; Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the RNA kissing-loop complex formed by the HIV-1 genomic RNA dimerization initiation site (DIS) spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e5cdddbf818153905898e8f0057b4e
https://pubmed.ncbi.nlm.nih.gov/17942426

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