Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Séverine Deforges"'
Autor:
Nan Jiang, Dario Cupolillo, Noelle Grosjean, Emeline Muller, Séverine Deforges, Christophe Mulle, Thierry Amédée
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105345- (2021)
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by cognitive decline related to deficits in synaptic transmission and plasticity. We report in APP/PS1 mice, a double transgenic mouse model of AD, that females display
Externí odkaz:
https://doaj.org/article/89ce528e291a429f9623e2632bed57d6
Autor:
Céline Desseille, Séverine Deforges, Olivier Biondi, Léo Houdebine, Domenico D’amico, Antonin Lamazière, Cédric Caradeuc, Gildas Bertho, Gaëlle Bruneteau, Laure Weill, Jean Bastin, Fatima Djouadi, François Salachas, Philippe Lopes, Christophe Chanoine, Charbel Massaad, Frédéric Charbonnier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Amyotrophic Lateral Sclerosis is an adult-onset neurodegenerative disease characterized by the specific loss of motor neurons, leading to muscle paralysis and death. Although the cellular mechanisms underlying amyotrophic lateral sclerosis (ALS)-indu
Externí odkaz:
https://doaj.org/article/93e08f1473ec471cac23c066507b727c
Autor:
Gaël Barthet, Ana Moreira-de-Sá, Pei Zhang, Séverine Deforges, Jorge Castanheira, Adam Gorlewicz, Christophe Mulle
Publikováno v:
J Neurosci
Kainate receptors (KARs) form a family of ionotropic glutamate receptors that regulate the activity of neuronal networks by both presynaptic and postsynaptic mechanisms. Their implication in pathologies is well documented for epilepsy. The higher pre
Autor:
Thierry Amédée, Dario Cupolillo, Emeline Muller, Noelle Grosjean, Séverine Deforges, Nan Jiang, Christophe Mulle
Publikováno v:
Neurobiology of Disease, Vol 154, Iss, Pp 105345-(2021)
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 154, ⟨10.1016/j.nbd.2021.105345⟩
Neurobiology of Disease, Elsevier, 2021, 154, pp.105345. ⟨10.1016/j.nbd.2021.105345⟩
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 154, ⟨10.1016/j.nbd.2021.105345⟩
Neurobiology of Disease, Elsevier, 2021, 154, pp.105345. ⟨10.1016/j.nbd.2021.105345⟩
International audience; Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by cognitive decline related to deficits in synaptic transmission and plasticity. We report in APP/PS1 mice, a double transgenic mouse model of
Autor:
Stéphane J. Baudouin, April R. Giles, Nick Pearson, Severine Deforges, Chenxia He, Céline Boileau, Nicolas Partouche, Andreas Borta, Justine Gautron, Morgane Wartel, Irena Bočkaj, Didier Scavarda, Fabrice Bartolomei, Guillaume Penchet, Jérôme Aupy, Jennifer Sims, Jared Smith, Andrew Mercer, Olivier Danos, Christophe Mulle, Valérie Crépel, Richard Porter
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101342- (2024)
Mesial temporal lobe epilepsy (mTLE) is the most prevalent type of epilepsy in adults. First and subsequent generations of anti-epileptic therapy regimens fail to decrease seizures in a large number of patients suffering from mTLE, leaving surgical a
Externí odkaz:
https://doaj.org/article/b7eefb3836e346488c8327be3214fc97
Autor:
Vincent, Maingret, Gaël, Barthet, Séverine, Deforges, Nan, Jiang, Christophe, Mulle, Thierry, Amédée
Publikováno v:
Neurobiology of aging. 50
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by early cognitive deficits linked to synaptic dysfunction and loss. Considerable evidence suggests that neuroinflammation contributes to AD. Prostaglandin E
Autor:
Claude Pariset, Sylvie Lécolle, Olivier Biondi, Jocelyn Côté, Camille Lancelin, Gabriel Sanchez, Frédéric Charbonnier, Séverine Deforges, Philippe Lopes, Julien Branchu, Christophe Chanoine
Publikováno v:
The Journal of Neuroscience. 30:11288-11299
Spinal muscular atrophy (SMA), a lethal neurodegenerative disease that occurs in childhood, is caused by the misexpression of the survival of motor neuron (SMN) protein in motor neurons. It is still unclear whether activating motor units in SMA corre
Autor:
Julien Branchu, Philippe Lopes, Claude Pariset, Christophe Chanoine, Frédéric Charbonnier, Séverine Deforges, Sylvie Lécolle, Clément Grondard, Olivier Biondi, Pierre-Paul Vidal
Publikováno v:
The Journal of Physiology. 587:3561-3572
Several studies using transgenic mouse models of familial amyotrophic lateral sclerosis (ALS) have reported a life span increase in exercised animals, as long as animals are submitted to a moderate-intensity training protocol. However, the neuroprote
Autor:
Hung Li, Philippe Lopes, Sylvie Lécolle, Séverine Deforges, Carmen Cifuentes-Diaz, Bruno Della Gaspera, Frédéric Charbonnier, Christophe Chanoine, Clément Grondard, Claude Pariset, Olivier Biondi
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. ⟨10.1523/JNEUROSCI.3237-07.2008⟩
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. <10.1523/JNEUROSCI.3237-07.2008>
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. ⟨10.1523/JNEUROSCI.3237-07.2008⟩
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. <10.1523/JNEUROSCI.3237-07.2008>
Spinal muscular atrophy (SMA) is an inborn neuromuscular disorder caused by low levels of survival motor neuron protein, and for which no efficient therapy exists. Here, we show that the slower rate of postnatal motor-unit maturation observed in type
Autor:
Nicolas Vibert, Daniel Eugène, Pierre-Paul Vidal, L. E. Moore, Erwin Idoux, F. Guimont, Séverine Deforges
Publikováno v:
The Journal of Physiology. 583:923-943
The effect of the lack of vestibular input on the membrane properties of central vestibular neurons was studied by using a strain of transgenic, vestibular-deficient mutant KCNE1(-/-) mice where the hair cells of the inner ear degenerate just after b