Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Séverine Celton-Morizur"'
Autor:
Vanessa Maillet, Nadia Boussetta, Jocelyne Leclerc, Véronique Fauveau, Marc Foretz, Benoit Viollet, Jean-Pierre Couty, Séverine Celton-Morizur, Christine Perret, Chantal Desdouets
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 1994-2005 (2018)
Summary: Liver kinase B1 (LKB1) is involved in several biological processes and is a key regulator of hepatic metabolism and polarity. Here, we demonstrate that the master kinase LKB1 plays a dual role in liver regeneration, independently of its majo
Externí odkaz:
https://doaj.org/article/aaefdd6b409e402988f53a843dabb732
Publikováno v:
International Journal of Hepatology, Vol 2012 (2012)
Most cells in mammalian tissues usually contain a diploid complement of chromosomes. However, numerous studies have demonstrated a major role of “diploid-polyploid conversion” during physiopathological processes in several tissues. In the liver p
Externí odkaz:
https://doaj.org/article/0fbaad78ad1c4eea831a4a448a4faa2d
Publikováno v:
Cancers
Cancers, MDPI, 2021, 13 (20), pp.5151. ⟨10.3390/cancers13205151⟩
Cancers, Vol 13, Iss 5151, p 5151 (2021)
Cancers, MDPI, 2021, 13 (20), pp.5151. ⟨10.3390/cancers13205151⟩
Cancers, Vol 13, Iss 5151, p 5151 (2021)
Simple Summary Polyploidy, a balanced amplification of the genome is a defining feature of the liver. Up to 90% of adult hepatocytes in rodents and around 40% of those in humans are polyploid. The polyploidy of these cells depends on both the DNA con
Publikováno v:
médecine/sciences. 35:519-526
La polyploïdie (amplification du génome entier) fait référence à des organismes dont les cellules ont plus de deux jeux complets de chromosomes homologues. La polyploïdie a été observée pour la première fois chez les plantes, il y a plus d'
Autor:
Stefano Caruso, Anne-Marie Crain-Denoyelle, Marie Anson, Antoine L’Hermitte, Jessica Zucman-Rossi, Séverine Celton-Morizur, Sandrine Pham, Mathilde Cadoux, Gabrielle Couchy, Satoshi Yamagoe, Chantal Desdouets, Jean-Pierre Couty
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
Hepatology, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
Hepatology, Wiley-Blackwell, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
Hepatology, 2019, 69 (1), pp.160-178. ⟨10.1002/hep.30140⟩
International audience; Leukocyte cell-derived chemotaxin-2 (LECT2) was originally identified as a hepatocyte-secreted chemokine-like factor and a positive target of β-catenin signaling. Here, we dissected out the mechanisms by which LECT2 modulates
Autor:
Rozenn Riou, Angélique Gougelet, Robin Loesch, Cong Trung Nguyen, Nadia Guerra, Julien Calderaro, Jean-Pierre Couty, Jessica Zucman-Rossi, Sandrine Pham, Chantal Desdouets, Stefano Caruso, Sabine Colnot, Séverine Celton-Morizur, Mathilde Cadoux, Céline Pophillat
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2021, ⟨10.1016/j.jhep.2021.01.017⟩
Journal of Hepatology, Elsevier, 2021, ⟨10.1016/j.jhep.2021.01.017⟩
Background & Aims The NKG2D system is a potent immunosurveillance mechanism in cancer, wherein the activating NK cell receptor (NKG2D) on immune cells recognises its cognate ligands on tumour cells. Herein, we evaluated the expression of NKG2D ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc5181677241666a18c0389bba58fb0
https://hal.archives-ouvertes.fr/hal-03140512
https://hal.archives-ouvertes.fr/hal-03140512
Autor:
Nadia Boussetta, Sandrine Pham, Jean-Pierre Couty, Chantal Desdouets, Séverine Celton-Morizur, Manon Fortier, Mathilde Cadoux, Romain Donne
Publikováno v:
Scientific Reports
Scientific Reports, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Nature Publishing Group, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Nature Publishing Group, 2019, 9, pp.14614. ⟨10.1038/s41598-019-51175-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Mammalian p38α MAPK (Mitogen-Activated Protein Kinase) transduces a variety of extracellular signals that regulate cellular processes, such as inflammation, differentiation, proliferation or apoptosis. In the liver, depending of the physiopathologic
Publikováno v:
Medecine sciences : M/S. 35(6-7)
Polyploidy (alias whole genome amplification) refers to organisms containing more than two basic sets of chromosomes. Polyploidy was first observed in plants more than a century ago, and it is known that such processes occur in many eukaryotes under
Autor:
Manon, Fortier, Mathilde, Cadoux, Nadia, Boussetta, Sandrine, Pham, Romain, Donné, Jean-Pierre, Couty, Chantal, Desdouets, Séverine, Celton-Morizur
Publikováno v:
Scientific Reports
Mammalian p38α MAPK (Mitogen-Activated Protein Kinase) transduces a variety of extracellular signals that regulate cellular processes, such as inflammation, differentiation, proliferation or apoptosis. In the liver, depending of the physiopathologic
Autor:
Jean-Pierre Couty, Valérie Paradis, Géraldine Gentric, Miguel Albuquerque, Romain Donne, Christophe Klein, Chantal Desdouets, Antoine L’Hermitte, Jessica Zucman-Rossi, Julien Calderaro, Thomas Guilbert, Mathilde Cadoux, Gabrielle Couchy, Stefano Caruso, Séverine Celton-Morizur, Myriam Bou-Nader
Publikováno v:
Gut
Gut, BMJ Publishing Group, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
Gut, BMJ Publishing Group, 2020, 69 (2), pp.355-364. ⟨10.1136/gutjnl-2018-318021⟩
Gut, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
Gut, BMJ Publishing Group, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
Gut, BMJ Publishing Group, 2020, 69 (2), pp.355-364. ⟨10.1136/gutjnl-2018-318021⟩
Gut, In press, pp.gutjnl-2018-318021. ⟨10.1136/gutjnl-2018-318021⟩
ObjectivesPolyploidy is a fascinating characteristic of liver parenchyma. Hepatocyte polyploidy depends on the DNA content of each nucleus (nuclear ploidy) and the number of nuclei per cell (cellular ploidy). Which role can be assigned to polyploidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee5f7b20cd3a1905f8faaad785675cd
https://hal.sorbonne-universite.fr/hal-02102441/file/gutjnl-2018-318021.full.pdf
https://hal.sorbonne-universite.fr/hal-02102441/file/gutjnl-2018-318021.full.pdf