Results of a Randomized Clinical Trial of Speech after Early Neurostimulation in Parkinson's Disease

Autor: Serge, Pinto, Adelheid, Nebel, Jörn, Rau, Robert, Espesser, Pauline, Maillochon, Oliver, Niebuhr, Paul, Krack, Tatiana, Witjas, Alain, Ghio, Marie-Charlotte, Cuartero, Lars, Timmermann, Alfons, Schnitzler, Helke, Hesekamp, Niklaus, Meier, Julia, Müllner, Thomas D, Hälbig, Bettina, Möller, Steffen, Paschen, Laura, Paschen, Jens, Volkmann, Michael T, Barbe, Gereon R, Fink, Johannes, Becker, Paul, Reker, Andrea A, Kühn, Gerd-Helge, Schneider, Valérie, Fraix, Eric, Seigneuret, Andrea, Kistner, Olivier, Rascol, Christine, Brefel-Courbon, Fabienne, Ory-Magne, Christian J, Hartmann, Lars, Wojtecki, Anne, Fradet, David, Maltête, Philippe, Damier, Séverine, Le Dily, Friederike, Sixel-Döring, Petra, Benecke, Daniel, Weiss, Tobias, Wächter, Marcus O, Pinsker, Jean, Régis, Stéphane, Thobois, Gustavo, Polo, Jean-Luc, Houeto, Andreas, Hartmann, Karina, Knudsen, Marie, Vidailhet, Michael, Schüpbach, Günther, Deuschl

Publikováno v: Movement Disorders
Movement Disorders, 2023, 38 (2), pp.212-222. ⟨10.1002/mds.29282⟩

The EARLYSTIM trial demonstrated for Parkinson's disease patients with early motor complications that deep brain stimulation of the subthalamic nucleus (STN-DBS) and best medical treatment (BMT) was superior to BMT alone.This prospective, ancillary s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeae006c89cde3cf9af9998b08b4e56c
https://pubmed.ncbi.nlm.nih.gov/36461899

Colonic neuropathology is not associated with autonomic dysfunction in Parkinson's disease

Autor: Yann Péréon, Laurène Leclair-Visonneau, Fabienne Vavasseur, Thomas Clairembault, Pascal Derkinderen, Séverine Le Dily, Emmanuel Coron, Christelle Volteau, Guillaume Chapelet, Michel Neunlist, Cécile Preterre

Publikováno v: Parkinsonism and Related Disorders
Parkinsonism and Related Disorders, Elsevier, 2019, 61, pp.224-227. ⟨10.1016/j.parkreldis.2018.09.021⟩

Introduction Dysautonomia in Parkinson's disease (PD) has been shown to be associated with disease severity and especially with the occurrence of dementia. One proposed explanation for this finding is that phosphorylated alpha-synuclein histopatholog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d70db44528d08c49b1cd905ed6f56e0
https://doi.org/10.1016/j.parkreldis.2018.09.021

Heterogeneous pattern of autonomic dysfunction in Parkinson's disease

Autor: Thomas Clairembault, Cécile Preterre, Yann Péréon, Philippe Damier, Laurent Magy, Pascal Derkinderen, Laurène Leclair-Visonneau, Arnaud Peyre, Michel Neunlist, Séverine Le Dily, Christelle Volteau

Publikováno v: Journal of neurology. 265(4)

Dysautonomic symptoms are frequent non-motor complaints in patients with Parkinson's disease. Numerous neuropathological studies have shown that Lewy bodies and neurites, the pathological hallmarks of Parkinson's disease, are widely distributed throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8903a1bd71b1786e00bcfb545391e584
https://pubmed.ncbi.nlm.nih.gov/29464374

Structural alterations of the intestinal epithelial barrier in Parkinson’s disease

Autor: Marie-Françoise Heymann, Thomas Clairembault, Séverine Le Dily, Michel Neunlist, Arnaud Bourreille, Emmanuel Coron, Laurène Leclair-Visonneau, Pascal Derkinderen, Fabienne Vavasseur

Publikováno v: Acta Neuropathologica Communications

Functional and morphological alterations of the intestinal epithelial barrier (IEB) have been consistently reported in digestive disorders such as irritable bowel syndrome and inflammatory bowel disease. There is mounting evidence that Parkinson’s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f770e231158489962fe6e5c15ebb55e1
https://doi.org/10.1186/s40478-015-0196-0