Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sérgio José Macedo-Júnior"'
Autor:
Francisney Pinto Nascimento, Sérgio José Macedo-Júnior, Fernanda Rocha Lapa-Costa, Fernando Cezar-dos-Santos, Adair R. S. Santos
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Since the 1970s, when ATP was identified as a co-transmitter in sympathetic and parasympathetic nerves, it and its active metabolite adenosine have been considered relevant signaling molecules in biological and pathological processes in the central n
Externí odkaz:
https://doaj.org/article/d43cdec9b9284320add6a3e38196df2a
Autor:
Fernando Cezar-Dos-Santos, Francisney Pinto do Nascimento, Fernanda Rocha Lapa-Costa, Sérgio José Macedo-Júnior, Adair R.S. Santos
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
Since the 1970s, when ATP was identified as a co-transmitter in sympathetic and parasympathetic nerves, it and its active metabolite adenosine have been considered relevant signaling molecules in biological and pathological processes in the central n
Autor:
Marina Delgobo, Samantha C. Lopes, Raquel Nascimento das Neves, Alfeu Zanotto-Filho, Rosângela Mayer Gonçalves, José Cláudio Fonseca Moreira, Juliano Ferreira, Fernando Spiller, Sérgio José Macedo-Júnior, Débora Denardin Lückemeyer, Vitória Wibbelt dos Santos, Jonathan Paulo Agnes, Daniel Pens Gelain, Rui Daniel Prediger, Carolina Saibro Girardi, Marcella de Amorim Ferreira
Publikováno v:
The journal of pain. 22(8)
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a common, difficult-to-treat, and dose-limiting side effect associated with Oxaliplatin (OXA) treatment. In this study, we evaluated the effect of three antioxidants - namely N-acetylcysteine, α-l
Autor:
Francisney Pinto do Nascimento, Sérgio José Macedo-Júnior, Murilo Luiz-Cerutti, Adair R.S. Santos
Publikováno v:
Purinergic Signal
The role of peripheral adenosine receptors in pain is a controversial issue and seems to be quite different from the roles of spinal and central adenosine receptors. The present study is aimed at clarifying the role of these receptors in peripheral n
Autor:
Roberta Giusti Schran, Sérgio José Macedo-Júnior, Débora Denardin Lückemeyer, Marcella de Amorim Ferreira, Ana Merian Silva, Raquel Tonello, Arthur da Silveira Prudente, Juliano Ferreira
Publikováno v:
Brain Research. 1764:147438
Central sensitization (CS) is characteristic of difficult to treat painful conditions, such as fibromyalgia and neuropathies and have sexual dimorphism involved. The calcium influx in nociceptive neurons is a key trigger for CS and the role of Cav2.1
Autor:
Murilo Luiz-Cerutti, Daniel Martins, M.D. da Silva, R.P. Cremonese, Fábio Rodrigo Mesquita Borges, Sérgio José Macedo-Júnior, Ana Lúcia S. Rodrigues, Adair R.S. Santos, Francisney Pinto do Nascimento
Publikováno v:
Neuroscience. 303:51-58
Background: It has been shown that chronic pain is able to induce depressive disorders in humans, in part, due to peripheral inflammation that reaches the central nervous system. However, the mechanisms involved remain to be established. The purpose
Autor:
Adair R.S. Santos, Denise Bohrer do Nascimento, Murilo Luiz-Cerutti, Marcelo Farina, Alcíbia Helena de Azevedo Maia, Sérgio José Macedo-Júnior
Publikováno v:
Journal of toxicology and environmental health. Part A. 80(19-21)
Various studies on methylmercury (MeHg)-induced toxicity focused on the central nervous system (CNS) as a primary target. However, MeHg-mediated toxicity is related to metallic interaction with electrophilic groups, which are not solely restricted to
Autor:
Rafael C. Dutra, Francisney Pinto do Nascimento, Fabrício A. Pamplona, João B. Calixto, Adair R.S. Santos, Sérgio José Macedo-Júnior, Murilo Luiz-Cerutti, Jana Sawynok, Marina Machado Córdova, Carla I. Tasca, Leandra C. Constantino, Allison Reid
Publikováno v:
Molecular Neurobiology. 51:1368-1378
Inosine is an endogenous nucleoside that has anti-inflammatory and antinociceptive properties. Inosine is a metabolite of adenosine, and some of its actions suggest the involvement of adenosine A1 receptors (A1Rs). The purpose of this study was to be
Autor:
Murilo Luiz-Cerutti, Sérgio José Macedo-Júnior, Francisney Pinto do Nascimento, Adair R.S. Santos
Publikováno v:
Purinergic Signalling. 9:51-58
Inosine is the first metabolite of adenosine. It exerts an antinociceptive effect by activating the adenosine A(1) and A(2A) receptors. We have previously demonstrated that inosine exhibits antinociceptive properties in acute and chronic mice models
Publikováno v:
Pharmacology and Therapeutics
Since the late 1920s, the importance of the physiological role of adenosine triphosphate (ATP) and its metabolites, mainly adenosine, has been clear. In 1970, strong evidence now suggests ATP as a neurotransmitter in nonadrenergic, noncholinergic (NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9b844c7503b195817c2a32ab435f62
http://www.intechopen.com/articles/show/title/pharmacology-of-adenosine-receptors-and-their-signaling-role-in-immunity-and-inflammation
http://www.intechopen.com/articles/show/title/pharmacology-of-adenosine-receptors-and-their-signaling-role-in-immunity-and-inflammation