Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sérgio J. C. do Carmo"'
Autor:
Ivanna Hrynchak, Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Sérgio J. C. do Carmo, Roxana Cornoiu, Amílcar Falcão, Dana Niculae, Antero J. Abrunhosa
Publikováno v:
Molecules, Vol 28, Iss 12, p 4670 (2023)
Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being proposed as theranostic tools in multiple human diseases. While the production of copper-64 using solid targets has been established for many years, its use is limited
Externí odkaz:
https://doaj.org/article/2baf189e8d844e77878f52becd51db8c
Autor:
Alexandra I. Fonseca, Vítor H. Alves, Sérgio J. C. do Carmo, Magda Silva, Ivanna Hrynchak, Francisco Alves, Amílcar Falcão, Antero J. Abrunhosa
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 723 (2022)
PET imaging has gained significant momentum in the last few years, especially in the area of oncology, with an increasing focus on metal radioisotopes owing to their versatile chemistry and favourable physical properties. Copper-61 (t1/2 = 3.33 h, 61
Externí odkaz:
https://doaj.org/article/a2e0fb73e4574e5a99ea2c4ff6442773
Publikováno v:
Instruments, Vol 2, Iss 3, p 17 (2018)
An automated process for the production and purification of radiometals produced by irradiating liquid targets in a medical cyclotron, using a commercially available module, has been developed. The method is suitable for the production and purificati
Externí odkaz:
https://doaj.org/article/3d0968e4a6704ebdb2210b8ac59e6b86
Autor:
Abrunhosa, Ivanna Hrynchak, Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Sérgio J. C. do Carmo, Roxana Cornoiu, Amílcar Falcão, Dana Niculae, Antero J.
Publikováno v:
Molecules; Volume 28; Issue 12; Pages: 4670
Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being proposed as theranostic tools in multiple human diseases. While the production of copper-64 using solid targets has been established for many years, its use is limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4bcf8a8da6482bb5ce4d4b0f9dacd217
Autor:
Sergio J. C. do Carmo, Ângela C. B. Neves, Eric Kral, Jean-Michel Geets, Benoit Nactergal, Antero J. Abrunhosa, Francisco Alves
Publikováno v:
Instruments, Vol 8, Iss 3, p 38 (2024)
The implementation of the Variable Energy (VE) feature in the previously fixed-energy IBA Cyclone® Kiube cyclotron is presented as an upgrade enabling the production of novel radioisotopes with improved radionuclidic purity and production yields. Th
Externí odkaz:
https://doaj.org/article/23b0a9f49a874c13ab6ade65896d0408
Autor:
Sergio J. C. do Carmo, Francisco Alves
Publikováno v:
Instruments, Vol 8, Iss 2, p 33 (2024)
The present work promotes and validates the benefits of using niobium instead of Havar® as the material for the target windows in most routine irradiations in cyclotrons. Calculation of the material activation and measurements of the contamination o
Externí odkaz:
https://doaj.org/article/ff7e0872c12e4ac8aaf8fb8a58b2cd82
Autor:
Diana Cocioabă, Alexandra I. Fonseca, Radu Leonte, Ivanna Hrynchak, Roxana Tudoroiu-Cornoiu, Sergio J. C. do Carmo, Bogdan Burghelea, Simona Băruță, Ana Rita Almeida, Radu Șerban, Anca Dinischiotu, Antero J. Abrunhosa, Dana Niculae
Publikováno v:
Molecules, Vol 29, Iss 6, p 1390 (2024)
On the verge of a theranostic approach to personalised medicine, copper-64 is one of the emerging radioisotopes in nuclear medicine due to its exploitable nuclear and biochemical characteristics. The increased demand for copper-64 for preclinical and
Externí odkaz:
https://doaj.org/article/65aa69a591734cd7a2fe00914b4c8230
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-21 (2020)
Abstract Over the last several years, the use of radiometals has gained increasing relevance in supporting the continuous development of new, complementary and more specific biological targeting agents. Radiopharmaceuticals labelled with radiometals
Externí odkaz:
https://doaj.org/article/0b1b73002b6d4086bff2865cbce07771
Autor:
Sergio J. C. do Carmo, Francisco Alves
Publikováno v:
Instruments, Vol 6, Iss 1, p 3 (2022)
The present work describes a method to determine excitation function curves and, therefore, cross-sections, making use of the irradiation of liquid targets at distinct energies in a biomedical cyclotron. The method relies on the derivative of experim
Externí odkaz:
https://doaj.org/article/9d096d7f48204aee9b3e4122184f91e8
Publikováno v:
Applied Sciences, Vol 11, Iss 22, p 10922 (2021)
This work presents a simulation model developed with the aim to represent and study the thermal behavior of cyclotron liquid targets. Understanding and improving the thermal behavior of the target system is fundamental to improving the target overall
Externí odkaz:
https://doaj.org/article/cf466309d7a64cefa88d5475582ecf2d