Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Sérgio, de Albuquerque"'
Autor:
Meiry L. Lacerda, Carla D. Lopes, Raphael T.C. Silva, Renan D. Zanetti, Mariete B. Moreira, Adelino V.G. Netto, Wesley A. Souza, Sérgio de Albuquerque, Drielly A. Paixão, Wendell Guerra
Publikováno v:
Chemistry of Inorganic Materials, Vol 3, Iss , Pp 100049- (2024)
In this work, a new platinum(II) complex was prepared by the reaction of K2PtCl4 with 1,4-benzodioxan-6-amine (bda) at room temperature in the molar ratio 2:1 (L:M). The complex was characterized by physicochemical (elemental analysis, TGA/DTA, and c
Externí odkaz:
https://doaj.org/article/ee982abcbc0a4816b9cc26a8985ae8e8
Autor:
Glaucio Monteiro Ferreira, Thales Kronenberger, Vinicius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor Medeiros Almeida, Sandro Roberto Marana, Carla Duque Lopes, Daiane Yukie Tezuka, Sérgio de Albuquerque, Flavio da Silva Emery, Gustavo Henrique Goulart Trossini
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 428 (2023)
Trypanosoma cruzi, the etiological agent of Chagas disease, relies on finely coordinated epigenetic regulation during the transition between hosts. Herein we targeted the silent information regulator 2 (Sir2) enzyme, a NAD+-dependent class III histon
Externí odkaz:
https://doaj.org/article/1982c52c73ab40ffae0e62189ec84db7
Autor:
Drielly A. Paixão, Carla D. Lopes, Zumira A. Carneiro, Luana M. Sousa, Leticia P. de Oliveira, Norberto P. Lopes, Marcos Pivatto, Joana Darc S. Chaves, Mauro V. de Almeida, Javier Ellena, Mariete B. Moreira, Adelino V.G. Netto, Ronaldo J. de Oliveira, Silvana Guilardi, Sérgio de Albuquerque, Wendell Guerra
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 157-166 (2019)
In order to improve the previously observed antichagasic activity of Cu(II) complexes containing 2-chlorobenzhydrazide (2-CH), we report herein the synthesis and anti-Trypanosoma cruzi activity of novel copper complexes containing 2-methoxybenzhydraz
Externí odkaz:
https://doaj.org/article/6556df07ab6246f0b61cfa4933a4ad4d
Publikováno v:
RAC: Revista de Administração Contemporânea, Vol 25, Iss 4, Pp e210055-e210055 (2021)
Futebol é uma paixão nacional. Todos, no Brasil, já ouviram essa frase alguma vez. E ela expressa uma verdade irretocável. Realmente, se há um esporte genuinamente popular no maior país da América Latina e que, ao mesmo tempo, atrai o interess
Externí odkaz:
https://doaj.org/article/ffad3e5cb0874251b1444c554c3207c0
Autor:
Julia M. Souza, Tatiana M. Vieira, Ana Carolina B.B. Candido, Daiane Y. Tezuka, G. Subba Rao, Sérgio de Albuquerque, Antônio E.M. Crotti, Jair L. Siqueira-Neto, Lizandra G. Magalhães
Publikováno v:
Current Research in Parasitology and Vector-Borne Diseases, Vol 1, Iss , Pp 100031- (2021)
Chagas disease is a tropical disease caused by the protozoan parasite Trypanosoma cruzi and currently affects millions of people worldwide. Curcumin (CUR), the major constituent of turmeric spice (dry powder of Curcuma longa L. plant rhizomes and roo
Externí odkaz:
https://doaj.org/article/168a9d5f74c942abb6407657d91a07c2
Autor:
Ana Camila Micheletti, Neli Kika Honda, Paola Dias de Oliveira, Dênis Pires de Lima, Adilson Beatriz, Sérgio de Albuquerque
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 12, Iss 3 (2020)
A series of xanthone derivatives containing different side chains, including ω-bromo and ω-aminoalkoxylxanthones (with linear alkoxy chains of 3, 4 and 5 carbon atoms and methyl, propyl, tert-butylamino and piperidinyl moieties), synthesized from t
Externí odkaz:
https://doaj.org/article/cb72cc055a5f4d79aba1d63a156f586d
Autor:
Lorenzo Cianni, Carina Lemke, Erik Gilberg, Christian Feldmann, Fabiana Rosini, Fernanda Dos Reis Rocho, Jean F R Ribeiro, Daiane Y Tezuka, Carla D Lopes, Sérgio de Albuquerque, Jürgen Bajorath, Stefan Laufer, Andrei Leitão, Michael Gütschow, Carlos A Montanari
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0007755 (2020)
The cysteine protease cruzipain is considered to be a validated target for therapeutic intervention in the treatment of Chagas disease. A series of 26 new compounds were designed, synthesized, and tested against the recombinant cruzain (Cz) to map it
Externí odkaz:
https://doaj.org/article/3510716dcbcc410e83482bb1244acca6
Autor:
Drielly A. Paixão, Leticia P. de Oliveira, Pedro Ivo da S. Maia, Victor M. Deflon, Zumira A. Carneiro, Katia Júlia de Almeida, Norberto P. Lopes, Marcos Pivatto, Joana Darc S. Chaves, Sérgio de Albuquerque, Mauro V. de Almeida, Silvana Guilardi, Wendell Guerra
Publikováno v:
Journal of Saudi Chemical Society, Vol 22, Iss 7, Pp 809-815 (2018)
We report here the characterization of two new polymeric copper(II) complexes containing 2-chlorobenzhydrazide (2-CH) and two N,N-donor ligands, namely, 1,10-phenanthroline (phen) and 4-4′-dimethoxy-2-2′-bipyridine (dmb). The structure of a new p
Externí odkaz:
https://doaj.org/article/50a25a530dff40b9b162054267f5a88a
Autor:
Suzane Quintana Gomes, Leonardo Bruno Federico, Guilherme Martins Silva, Carla Duque Lopes, Sérgio de Albuquerque, Carlos Henrique Tomich de Paula da Silva
Chagas disease is a well-known Neglected Tropical Disease, mostly endemic in continental Latin America, but that has spread to North America and Europe. Unfortunately, current treatments against such disease are ineffective and produce known and unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548032c619f373abb2e2dd9a3d70a532
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 51, Iss 1, Pp 101-109 (2015)
Ursolic acid is a promising candidate for treatment of Chagas disease; however it has low aqueous solubility and intestinal absorption, which are both limiting factors for bioavailability. Among the strategies to enhance the solubility and dissolutio
Externí odkaz:
https://doaj.org/article/9e901aa0a4b54dffa29fd07088e6c0a6