Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Sérgia Velho"'
Publikováno v:
Gels, Vol 10, Iss 5, p 307 (2024)
Nanostructured lipid carriers (NLCs) have the potential to increase the bioavailability and reduce the side effects of docetaxel (DTX). However, only a small fraction of nanoparticles given intravenously can reach a solid tumor. In situ-forming gels
Externí odkaz:
https://doaj.org/article/70ecbc5deda34b0688dca78c7d426ab9
Publikováno v:
Life, Vol 14, Iss 4, p 489 (2024)
The specific interaction between cell surface receptors and corresponding antibodies has driven opportunities for developing targeted cancer therapies using nanoparticle systems. It is challenging to design and develop such targeted nanomedicines usi
Externí odkaz:
https://doaj.org/article/31566eb1b1a447e6a8708efd69815bc1
Publikováno v:
Gels, Vol 9, Iss 7, p 593 (2023)
The widespread push to invest in local cancer therapies comes from the need to overcome the limitations of systemic treatment options. In contrast to intravenous administration, local treatments using intratumoral or peritumoral injections are indepe
Externí odkaz:
https://doaj.org/article/b1a049c812134accaf4bf9a90bef02c3
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 216 (2023)
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and lipid–polymer hybrid nan
Externí odkaz:
https://doaj.org/article/c74f0eacbc6747d89b144461c878c686
Autor:
Patrícia Carneiro, Ana Margarida Moreira, Joana Figueiredo, Rita Barros, Patrícia Oliveira, Maria Sofia Fernandes, Anabela Ferro, Raquel Almeida, Carla Oliveira, Fátima Carneiro, Fernando Schmitt, Joana Paredes, Sérgia Velho, Raquel Seruca
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background E-cadherin has been awarded a key role in the aetiology of both sporadic and hereditary forms of gastric cancer. In this study, we aimed to identify molecular interactors that influence the expression and function of E-cadherin as
Externí odkaz:
https://doaj.org/article/f4d68857c4854fe6aa506e715a3e18f9
Publikováno v:
Cells, Vol 11, Iss 16, p 2490 (2022)
KRAS mutations have been shown to extend their oncogenic effects beyond the cancer cell, influencing the tumor microenvironment. Herein, we studied the impact of mutant KRAS on the modulation of the pro-tumorigenic properties of cancer-associated fib
Externí odkaz:
https://doaj.org/article/ec2c3338ba0a4db2a804ca312c75175f
Publikováno v:
Cells, Vol 11, Iss 13, p 1988 (2022)
Understanding how mutant KRAS signaling is modulated by exogenous stimuli is of utmost importance to elucidate resistance mechanisms underlying pathway inhibition failure, and to uncover novel therapeutic targets for mutant KRAS patients. Hence, aimi
Externí odkaz:
https://doaj.org/article/ad7176ed763241caa3b73e09042363d7
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Tables 1 and 2 PDF file 91K, Table 1 contains clinical and genotypic data from the patient cohort referred to in Fig. 6. Table 2 contains shRNA target sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90a292b3f3f7482d1d060ada9b3e8f5
https://doi.org/10.1158/2159-8290.22530575
https://doi.org/10.1158/2159-8290.22530575
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Figure S3 PDF file 66K,Additional data related to the proliferative and apoptotic phenotypes of CRC cells expressing mutant Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1944ab43e95e00de6e3eb39c7c552d
https://doi.org/10.1158/2159-8290.22530590
https://doi.org/10.1158/2159-8290.22530590
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Figure Legends PDF file 72K, Legends for Supplementary Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c16078b4de56035cb8e2965a547dd63
https://doi.org/10.1158/2159-8290.22530599.v1
https://doi.org/10.1158/2159-8290.22530599.v1