Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sébastien Tabruyn"'
Autor:
Sonia Cinque, Yvessa Verheyden, Vicky Katopodi, Zorica Knezevic, Ewout Demesmaeker, Sara Adnane, Sarah Hanache, Roberto Vendramin, Fabian Stinkens, Felicia Vervloesem, Alessandro Cuomo, Joanna Pozniak, Alvaro Cortes Calabuig, Sébastien Tabruyn, Oliver Bechter, Maria Francesca Baietti, Elisabetta Groaz, Tiziana Bonaldi, Eleonora Leucci
Responses to anticancer therapies in patients with advanced metastatic disease are often lower than 50% and the majority of patients initially responding develop resistance later on. Therapy resistance often follows an adaptation phase in which cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::543a55e7c9dacb7cee425a820dc5ecf1
https://doi.org/10.1101/2023.01.06.523012
https://doi.org/10.1101/2023.01.06.523012
Autor:
Sonia Cinque, Yvessa Verheyden, Vicky Katopodi, Zorica Knezevic, Ewout Demesmaeker, Sara Adnane, Sarah Hanache, Roberto Vendramin, Fabian Stinkens, Felicia Vervloesem, Alessandro Cuomo, Joanna Pozniak, Alvaro Cortes Calabuig, Sébastien Tabruyn, Oliver Bechter, Maria Francesca Baietti, Elisabetta Groaz, Tiziana Bonaldi, Eleonora Leucci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0089d146221b5fbdd46a84f260c366b7
https://doi.org/10.2139/ssrn.4430396
https://doi.org/10.2139/ssrn.4430396
Autor:
Michel Aurrand-Lions, Mélanie Quintero, Christian Righini, Jean-François Mayol, Nathalie Sturm, Benoit Manfroi, Sébastien Tabruyn, Jérôme Moreaux, Bertrand Huard, Maria De Grandis
Publikováno v:
Blood Advances
Blood Advances, 2021, 5 (21), pp.4338-4351. ⟨10.1182/bloodadvances.2021004203⟩
Blood Advances, 2021, 5 (21), pp.4338-4351. ⟨10.1182/bloodadvances.2021004203⟩
Key Points CCL5 is differentially expressed by DLBCL cells and efficiently recruits TAMs through their expression of CCR1/CCR5.Most DLBCL TAMs have a noncanonical gene signature.
Visual Abstract
Tissue invasion by tumor cells induces a host
Visual Abstract
Tissue invasion by tumor cells induces a host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b905bb6dae03ebbe454b9d542e767ef
https://hal.science/hal-03531067
https://hal.science/hal-03531067
Autor:
Christophe Ferrand, Etienne Daguindau, Francine Garnache-Ottou, Sabeha Biichle, Cyril Faure, Mathieu Neto Da Rocha, Denis Caillot, Eric Deconinck, Fabrice Larosa, Séverine Valmary-Degano, Olivier Adotevi, Marina Deschamps, Rim Trad, Sébastien Tabruyn, Ziad Fajloun, Marius Moldovan, Walid Warda
Publikováno v:
Cancer Research. 79:663-675
Chronic myeloid leukemia (CML) is a chronic disease resulting in myeloid cell expansion through expression of the BCR-ABL1 fusion transcript. Tyrosine kinase inhibitors (TKI) have significantly increased survival of patients with CML, and deep respon
Autor:
Mary Callanan, Martin J. S. Dyer, Alexandar Tzankov, Thomas Alexander Mckee, Pascal Schneider, Sebastien Moret, Bertrand Huard, Jean Francois Mayol, Nathalie Sturm, Christian Righini, Benoit Manfroi, Sébastien Tabruyn, Christian L. Villiers, Thomas Matthes
Publikováno v:
Cancer Research
Cancer research, vol. 77, no. 5, pp. 1097-1107
Cancer Research, Vol. 77, No 5 (2017) pp. 1097-1107
Cancer research, vol. 77, no. 5, pp. 1097-1107
Cancer Research, Vol. 77, No 5 (2017) pp. 1097-1107
Tumor-infiltrating neutrophils have been implicated in malignant development and progression, but mechanisms are ill defined. Neutrophils produce a proliferation-inducing ligand APRIL/TNFSF13, a factor that promotes development of tumors from diverse
Autor:
Natasha L. Harvey, Jan Kazenwadel, Chan-Eng Chong, Genevieve A. Secker, Jacqueline M. Matthews, David M. Lawrence, Kelly L. Betterman, Sébastien Tabruyn, Cansaran Saygili Demir, Philippa H. Stokes, Yan Agalarov, Naoyuki Miura, Young Koung Lee, Tatiana V. Petrova, Drew L. Sutton, Marjo Salminen, Hamish S. Scott, Christopher N. Hahn
Publikováno v:
The Journal of clinical investigation
Journal of Clinical Investigation, vol. 125, no. 8, pp. 2979-2994
Journal of Clinical Investigation, vol. 125, no. 8, pp. 2979-2994
Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including Emberger syndrome, a disorder characterized by lymphedema and predisposition to myelodysplast
Autor:
Ingrid Struman, Karolien Castermans, Arash Haghikia, Ngoc-Quynh-Nhu Nguyen, Julie Halkein, Michaela Scherr, Melanie Ricke-Hoch, Denise Hilfiker-Kleiner, Joseph Martial, Sébastien Tabruyn, Marc Thiry, Karen Sliwa, Ludovic Malvaux, Vincent Lambert, Agnès Noël
Publikováno v:
Journal of Clinical Investigation; Vol 123
Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16-kDa N-terminal prolactin fragment (16K PRL), the underlying molecular mechanisms are poo
Autor:
Casey W. Williamson, Toshina Ishiguro-Oonuma, James G. Christensen, Dana T. Aftab, Ryan M. Naylor, Donald M. McDonald, Sébastien Tabruyn, Harold A. Chapman, Vikash J. Bhagwandin, Ying Wei, Barbara Sennino, Weon-Kyoo You
Publikováno v:
Cancer Discovery. 2:270-287
Invasion and metastasis increase after the inhibition of VEGF signaling in some preclinical tumor models. In the present study we asked whether selective VEGF inhibition is sufficient to increase invasion and metastasis and whether selective c-Met in
Autor:
Gou Young Koh, David Epstein, Tohru Morisada, Alicia Adams, Katharine Colton, Harras B. Zaid, Sébastien Tabruyn, Peter Baluk, Tom Le, Shaun O'Brien, Donald M. McDonald, Erin Lashnits, Jonas Fuxe
Publikováno v:
The American Journal of Pathology. 178:2897-2909
Blood vessel leakiness is an early, transient event in acute inflammation but can also persist as vessels undergo remodeling in sustained inflammation. Angiopoietin/Tie2 signaling can reduce the leakiness through changes in endothelial cells. The rol
Autor:
Anthony J. Coyle, Katharine Colton, Jane Connor, Donald M. McDonald, Jonas Fuxe, Sébastien Tabruyn, Stanley J. Wiegand, Gavin Thurston, Tohru Morisada
Publikováno v:
The American Journal of Pathology. 177:3233-3244
Vascular remodeling is a feature of chronic inflammation during which capillaries transform into venules that expand the region of the vasculature in which leakage and leukocyte emigration both occur. Recently, we found that angiopoietin/Tie2 recepto