Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sébastien Perron"'
Publikováno v:
Journal of Software. :137-148
The complexity of current software and the various dependencies between their components can affect their reliability, in particular their ability to tolerate faults. In object-oriented software, the interactions derived from such dependencies can le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff1f76e058bca8fd759fc4a86b99ecb
https://doi.org/10.17706/jsw.17.4.137-148
https://doi.org/10.17706/jsw.17.4.137-148
Publikováno v:
Canadian Journal of General Internal Medicine. 16:14-18
Giant cell arteritis (GCA) is a primary vasculitis of large and medium-sized arteries. It is the most common vasculitis affecting the elderly. GCA involves the cranial branches of the carotid arteries and classically presents with cranial symptoms su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cf0a57b67bd0fb4ac04ad4f15d2ae0
https://doi.org/10.22374/cjgim.v16i3.474
https://doi.org/10.22374/cjgim.v16i3.474
Autor:
Sébastien Perron
La médecine nous permet de vivre plus vieux qu'avant, mais pas nécessairement moins malades. Comment vivre plus longtemps sans traîner des maladies chroniques comme des boulets jusqu'à notre dernier souffle? Comment faire en sorte que nos vieux j
Autor:
Jean Pierre Marquette, Andreas Karlsson, Sylvie Monget, Thomas Bertrand, Jean Christophe Carry, Frank Halley, Marc Antoine Perrin, Jean Paul Nicolas, Tsiala Benard, Angela Virone-Oddos, Luc Bertin, Céline Amara, Hélène Bonnevaux, Laurence Delbarre, Gilles Doerflinger, Pierre Yves Abecassis, Youssef El-Ahmad, Véronique Charrier, Victor Certal, Bruno Filoche-Romme, Florence Gruss-Leleu, Sébastien Perron, Alexey Rak, Patrick Richepin, Stephane Guerif, Carlos Garcia-Echeverria, Loic Vincent, Nadine Michot, Magali Mathieu, Véronique Loyau, Olivier Lemaitre, Maurice Brollo, Christoph Lengauer, Houlfa Guizani, Laurent Schio, Fabienne Thompson, Cécile Delorme
Publikováno v:
Journal of Medicinal Chemistry. 57:903-920
Compelling molecular biology publications have reported the implication of phosphoinositide kinase PI3Kβ in PTEN-deficient cell line growth and proliferation. These findings supported a scientific rationale for the development of PI3Kβ-specific inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c85553ea8c69d86eeaefddb3c7297b6
https://doi.org/10.1021/jm401642q
https://doi.org/10.1021/jm401642q
Publikováno v:
Organic Process Research & Development. 17:1568-1571
We report herein the isolation and characterization of (S)-(+)-tert-butyl-3-hydroxyazepane-1-carboxylate via resolution of the commercially available racemate, using chiral supercritical fluid chromatography (SFC). After optimization of the experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de939e59c31617d7ca1f14c0a5ac9086
https://doi.org/10.1021/op400274b
https://doi.org/10.1021/op400274b
Autor:
Cécile Delorme, Angela Virone-Oddos, Bernadette Tric, Audrey Louboutin, Fabienne Thompson, Christoph Lengauer, Loic Vincent, Nadine Michot, Isabelle Vade, Jean Paul Nicolas, Frank Halley, Youssef El-Ahmad, Bruno Filoche-Romme, Hélène Bonnevaux, Andreas Karlsson, Sylvie Monget, Renaud Morales, Victor Certal, Laurent Schio, Gilles Doerflinger, Sébastien Perron, Jean Christophe Carry, Pierre Yves Abecassis
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:6381-6384
From a HTS campaign, a new series of pyrimidone anilides exemplified by compound 1 has been identified with good inhibitory activity for the PI3Kβ isoform. The structure of compound 1 in PI3Kγ was solved revealing a binding mode in agreement with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a7ad294cd6eed46f1ac36681f76724
https://doi.org/10.1016/j.bmcl.2012.08.072
https://doi.org/10.1016/j.bmcl.2012.08.072
Publikováno v:
Computers and Fluids
Computers and Fluids, 2004, 33 (10), pp.1305-1333. ⟨10.1016/j.compfluid.2003.10.006⟩
Computers and Fluids, 2004, 33 (10), pp.1305-1333. ⟨10.1016/j.compfluid.2003.10.006⟩
A new method to solve the Navier–Stokes equations for incompressible viscous flows and the transport of a scalar quantity is proposed. This method is based upon a fractional time step scheme and the finite volume method on unstructured meshes. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a93f6331aa170e3626673e8c3e6312
https://doi.org/10.1016/j.compfluid.2003.10.006
https://doi.org/10.1016/j.compfluid.2003.10.006
Autor:
Kirsten Bjergarde, Cécile Delorme, Pierre-Yves Abecassis, Alain Krick, Jean-Paul Nicolas, Gilles Doerflinger, Sébastien Perron, Michel Murer, Houlfa Guizani, Bruno Filoche-Romme, Sylvette Lachaud, Ronan Le Moigne, Céline Prévost, Cécile Combeau, Jacques Mauger, Jean-Christophe Carry, Stéphanie Pouzieux, Laure Delarbre, Laurent Schio, Francois Clerc, Marie-Line Monteiro, Hervé Minoux, Sylvie Monget, Thomas Bertrand, Véronique Crocq-Stuerga, Ma Nina, Francis Gasse, Odile Angouillant-Boniface, Rémi Lebel, Sébastien Maignan, Sylvie Gontier, Anil Nair, Eric Parmantier
Publikováno v:
Journal of medicinal chemistry. 58(1)
The Aurora family of serine/threonine kinases is essential for mitosis. Their crucial role in cell cycle regulation and aberrant expression in a broad range of malignancies have been demonstrated and have prompted intensive search for small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efa98d742ac08ebfaa138362d1053b5
https://pubmed.ncbi.nlm.nih.gov/25369539
https://pubmed.ncbi.nlm.nih.gov/25369539
Autor:
Sébastien Perron
Publikováno v:
Résolution numérique d'écoulements 3 dimensions avec une nouvelle méthode de volumes finis pour maillages non structurés /
L'objectif de cette these de doctorat est de developper un nouveau schema numerique de resolution des equations 3D de Navier-Stokes. Les ecoulements consideres sont incompressibles et les proprietes physiques telle la viscosite peuvent etre variables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47339fbf8cc0f6e9fe21fe5996c65c9a
https://doi.org/10.1522/12770629
https://doi.org/10.1522/12770629