Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sébastien J. Thuault"'
Autor:
Ceri H. Davies, Andrew J Doherty, Andrew D. Randall, Sébastien J. Thuault, Sonia Piccinin, Zuner A. Bortolotto, Jon T. Brown, Graham L. Collingridge
Publikováno v:
Neuropharmacology. 55:459-463
It is well established that activation of group I metabotropic glutamate receptors (mGluRs) produces long-lasting alterations in synaptic efficacy. We now demonstrate that activation of mGluRs can also induce long-term alterations in synchronised net
Autor:
Christine M. Constantinople, Sébastien J. Thuault, Irene Chen, Randy M. Bruno, Steven A. Siegelbaum, Svetlana Vronskaya, Judy P. Zhu, Eric R. Kandel, Gaël Malleret, Matthew F. Nolan, Russell E. Nicholls, Andrey A. Panteleyev
Publikováno v:
Thuault, S J, Malleret, G, Constantinople, C M, Nicholls, R, Chen, I, Zhu, J, Panteleyev, A, Vronskaya, S, Nolan, M F, Bruno, R, Siegelbaum, S A & Kandel, E R 2013, ' Prefrontal Cortex HCN1 Channels Enable Intrinsic Persistent Neural Firing and Executive Memory Function ', Journal of Neuroscience, vol. 33, no. 34, pp. 13583-13599 . https://doi.org/10.1523/JNEUROSCI.2427-12.2013
In many cortical neurons, HCN1 channels are the major contributors to Ih, the hyperpolarization-activated current, which regulates the intrinsic properties of neurons and shapes their integration of synaptic inputs, paces rhythmic activity, and regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876db0417d4d7163408bb0693de3bb65
https://www.pure.ed.ac.uk/ws/files/13531154/Prefrontal_cortex_HCN1_channels_enable_intrinsic_persistent_neural_firing_and_executive_memory_function.pdf
https://www.pure.ed.ac.uk/ws/files/13531154/Prefrontal_cortex_HCN1_channels_enable_intrinsic_persistent_neural_firing_and_executive_memory_function.pdf
Autor:
Eric R. Kandel, Sébastien J. Thuault, Syed Abid Hussaini, Kimberly A. Kempadoo, Steven A. Siegelbaum
SUMMARY Hippocampal CA1 and CA3 pyramidal neuron place cells encode the spatial location of an animal through localized firing patterns called ‘‘place fields.’’ To explore the mechanisms that control place cell firing and their relationship t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb18a7863ec1f1c227606ac2d62f1b26
https://europepmc.org/articles/PMC4435580/
https://europepmc.org/articles/PMC4435580/
Autor:
Angus C. Nairn, Kelly T. Dineley, Maïté Hotte, Hugh C. Hemmings, Thérèse M. Jay, Sébastien J. Thuault
Publikováno v:
Synapse (New York, N.Y.). 61(1)
Specific patterns of stimulation applied in the ventral hippocampus produce long-term potentiation (LTP) of postsynaptic synapses in the prefrontal cortex in vivo. The induction of LTP is dependent on NMDA receptors and cAMP-dependant kinase (PKA) ac
Autor:
Kelly T. Dineley, Fabienne Lachaise, Maïté Hotte, Sébastien J. Thuault, Thérèse M. Jay, Hugh C. Hemmings, Angus C. Nairn
Publikováno v:
Behavioural brain research. 171(1)
We have recently shown a significant role of dopamine D1 receptors in recognition and temporal order memory retrieval for objects in rodents [Hotte M, Naudon L, Jay TM. Modulation of recognition and temporal order memory retrieval by dopamine D(1) re
Autor:
Sébastien J. Thuault, Graham L. Collingridge, Andrew D. Randall, Andrew R. Calver, Ceri H. Davies, Jon T. Brown
Publikováno v:
Epilepsy research. 65(1-2)
GABAergic synaptic transmission plays an important role in the patterning of epileptiform activity. We have previously shown that global loss of GABA(B) receptor function due to transgenic deletion of the GABA(B1) receptor subunit exacerbates epilept
Publikováno v:
Neuropharmacology. 43(2)
The hippocampus is well known for its susceptibility to epileptic seizures, in part because of its neuronal architecture that facilitates synchronization. Although synaptic networks are important for the genesis and spread of epileptiform activity, s
Autor:
Ya-Ting eLei, Sebastien J. Thuault, Pierre eLaunay, Robert eMargolskee, Eric R. Kandel, Steven A. Siegelbaum
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
In certain neurons from different brain regions, a brief burst of action potentials can activate a slow afterdepolarization (sADP) in the presence of muscarinic acetylcholine receptor agonists. The sADP, if suprathreshold, can contribute to persisten
Externí odkaz:
https://doaj.org/article/c45454b09dc647e49b664a8c1241d61d