Výsledky vyhledávání - "Sébastien Huault"

Akademický článek

An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers.

Autor: Krittalak Chakrabandhu, Sébastien Huault, Jérôme Durivault, Kévin Lang, Ly Ta Ngoc, Angelique Bole, Eszter Doma, Benoit Dérijard, Jean-Pierre Gérard, Michel Pierres, Anne-Odile Hueber

Publikováno v: PLoS Biology, Vol 14, Iss 3, p e1002401 (2016)

Demonstrations of both pro-apoptotic and pro-survival abilities of Fas (TNFRSF6/CD95/APO-1) have led to a shift from the exclusive "Fas apoptosis" to "Fas multisignals" paradigm and the acceptance that Fas-related therapies face a major challenge, as

Externí odkaz: https://doaj.org/article/1fb1d4ffabc3436098b9f496b5080dc0

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Chimeric virus-like particles (VLPs) designed from shrimp nodavirus (MrNV) capsid protein specifically target EGFR-positive human colorectal cancer cells

Autor: Krittalak Chakrabandhu, Orawan Thongsum, Charoonroj Chotwiwatthanakun, Sébastien Huault, Pitchanee Jariyapong, Chidchanok Chawiwithaya, Wattana Weerachatyanukul, Anne-Odile Hueber, Khwanthana Grataitong

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-95891-x⟩
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-95891-x⟩

Recombinant MrNV capsid protein has been shown to effectively deliver plasmid DNA and dsRNA into Sf9 insect cells and shrimp tissues. To extend its application to cancer cell-targeting drug delivery, we created three different types of chimeric MrNV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3a0ea0738ebfd396dc59f4b46c82d5
https://doi.org/10.1038/s41598-021-95891-x

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Site-Specific Detection of Tyrosine Phosphorylated CD95 Following Protein Separation by Conventional and Phospho-Protein Affinity SDS-PAGE

Autor: Krittalak, Chakrabandhu, Sébastien, Huault, Anne-Odile, Hueber

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1557

Phosphorylation of two tyrosines in the death domain of CD95 is a critical mechanism in determining the receptor's choices between cell death and survival signals. Recently, site-specific monoclonal antibodies against phosphorylated tyrosines of CD95

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1a6332f8e69dcc04105430c8db91739
https://pubmed.ncbi.nlm.nih.gov/28078592

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Site-Specific Detection of Tyrosine Phosphorylated CD95 Following Protein Separation by Conventional and Phospho-Protein Affinity SDS-PAGE

Autor: Sébastien Huault, Krittalak Chakrabandhu, Anne-Odile Hueber

Publikováno v: Methods in Molecular Biology ISBN: 9781493967780
CD95
CD95, 1557, Springer New York, pp.173-188, 2017, Methods in Molecular Biology, ⟨10.1007/978-1-4939-6780-3_16⟩
Methods Mol Biol
Methods Mol Biol, 1557, pp.173-188, 2017, ⟨10.1007/978-1-4939-6780-3_16⟩

International audience; Phosphorylation of two tyrosines in the death domain of CD95 is a critical mechanism in determining the receptor's choices between cell death and survival signals. Recently, site-specific monoclonal antibodies against phosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7748338ec4edcefe82204bc8e7b3dfd3
https://doi.org/10.1007/978-1-4939-6780-3_16

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An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers

Autor: Jérôme Durivault, Angélique Bole, Benoit Dérijard, Eszter Doma, Anne-Odile Hueber, Sébastien Huault, Krittalak Chakrabandhu, Ly Ta Ngoc, Kévin Lang, Michel Pierres, Jean-Pierre Gérard

Publikováno v: PLoS Biology
PLoS Biology, 2016, 14 (3), pp.e1002401. ⟨10.1371/journal.pbio.1002401⟩
PLoS Biology, Public Library of Science, 2016, 14 (3), pp.e1002401. ⟨10.1371/journal.pbio.1002401⟩
Plos Biology
Plos Biology, 2016, 14 (3), pp.e1002401. ⟨10.1371/journal.pbio.1002401⟩
PLoS Biology, Vol 14, Iss 3, p e1002401 (2016)

Demonstrations of both pro-apoptotic and pro-survival abilities of Fas (TNFRSF6/CD95/APO-1) have led to a shift from the exclusive “Fas apoptosis” to “Fas multisignals” paradigm and the acceptance that Fas-related therapies face a major chall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652761d477e35e8bb828df2b3f8e3326
https://hal.science/hal-01438523

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Distinctive molecular signaling in triple-negative breast cancer cell death triggered by hexadecylphosphocholine (miltefosine)

Autor: Sébastien Huault, Krittalak Chakrabandhu, Anne-Odile Hueber

Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2008, 582 (30), pp.4176-84. ⟨10.1016/j.febslet.2008.11.019⟩

International audience; This study describes the molecular signaling involved in the different cell death modes of triple-negative breast cancer cells induced by hexadecylphosphocholine (HePC/miltefosine), a clinically relevant anticancer alkylphosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afaa417c1a3af69a53626432c12ff95a
https://doi.org/10.1016/j.febslet.2008.11.019

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The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells

Autor: B. Martoglio, Sébastien Huault, E. Friedmann, Martin Zörnig, F. Guardiola-Serrano, W. S. Wels, Katharina Lückerath, N. Novac, Nathalie Cahuzac, Anne-Odile Hueber, Vladimir Kirkin

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2007, 14 (9), pp.1678-87. ⟨10.1038/sj.cdd.4402175⟩

Fas ligand (FasL) is a type II transmembrane protein belonging to the tumor necrosis factor family. Its binding to the cognate Fas receptor triggers the apoptosis that plays a pivotal role in the maintenance of immune system homeostasis. The cell dea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae03b22f8b1750953ae6208499d4a006
https://doi.org/10.1038/sj.cdd.4402175

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Palmitoylation is required for efficient Fas cell death signaling

Autor: Sébastien Huault, Hai-Tao He, Krittalak Chakrabandhu, Britta Dost, Zoltán Hérincs, Fabien Conchonaud, Anne-Odile Hueber, Didier Marguet, Ling Peng

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2007, 26 (1), pp.209-20. ⟨10.1038/sj.emboj.7601456⟩
EMBO Journal, 2007, 26 (1), pp.209-20. ⟨10.1038/sj.emboj.7601456⟩

Localization of the death receptor Fas to specialized membrane microdomains is crucial to Fas-mediated cell death signaling. Here, we report that the post-translational modification of Fas by palmitoylation at the membrane proximal cysteine residue i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d702110ae6d7795e037298502098d74
https://doi.org/10.1038/sj.emboj.7601456

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Interferon decreases VEGF levels in patients with chronic myeloid leukemia treated with imatinib

Autor: Mahon Fx, François Guilhot, Joelle Guilhot, Anne-Odile Hueber, Laurence Legros, Claude Preudhomme, Sébastien Huault

Publikováno v: Leukemia Research
Leukemia Research, 2014, 38 (6), pp.662-665. ⟨10.1016/j.leukres.2014.01.010⟩
Leukemia Research, Elsevier, 2014, 38 (6), pp.662-665. ⟨10.1016/j.leukres.2014.01.010⟩

International audience; In chronic myeloid leukemia (CML), evidence is supporting the role of VEGF in growth, and survival of leukemia cells. The evaluation of plasma VEGF levels in 403 CML patients randomized within SPIRIT study to received imatinib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b4918fae33f521a156c6a33ddb9073
https://www.hal.inserm.fr/inserm-03360989/document

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