Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sébastien Fiorucci"'
Autor:
Cédric Bouysset, Sébastien Fiorucci
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-9 (2021)
Abstract Interaction fingerprints are vector representations that summarize the three-dimensional nature of interactions in molecular complexes, typically formed between a protein and a ligand. This kind of encoding has found many applications in dru
Externí odkaz:
https://doaj.org/article/b80815d56a404d318b8aa6f615e5059f
Autor:
Nadège Parassol, Céline Bienvenu, Cécile Boglio, Sébastien Fiorucci, Delphine Cerezo, Xiao-Min Yu, Guilhem Godeau, Jacques Greiner, Pierre Vierling, Stéphane Noselli, Christophe Di Giorgio, Véronique Van De Bor
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82908 (2013)
Molecular motors transport various cargoes including vesicles, proteins and mRNAs, to distinct intracellular compartments. A significant challenge in the field of nanotechnology is to improve drug nuclear delivery by engineering nanocarriers transpor
Externí odkaz:
https://doaj.org/article/cbe7955472244aad90dc7f7e0169b054
Autor:
Mee-Ra Rhyu, Sébastien Fiorucci, Jérôme Golebiowski, Jérémie Topin, Yi-Seul Kim, Jody Pacalon, Cédric Bouysset
Publikováno v:
Cellular and Molecular Life Sciences. 78:7605-7615
Bitter taste receptors (TAS2Rs) are a poorly understood subgroup of G protein-coupled receptors (GPCRs). The experimental structure of these receptors has yet to be determined, and key-residues controlling their function remain mostly unknown. We des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ae6d34bc79c5e6f08acefb61587718
https://doi.org/10.1007/s00018-021-03968-7
https://doi.org/10.1007/s00018-021-03968-7
Autor:
Sébastien Fiorucci, Cédric Bouysset
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-9 (2021)
Journal of Cheminformatics
Journal of Cheminformatics
Interaction fingerprints are vector representations that summarize the three-dimensional nature of interactions in molecular complexes, typically formed between a protein and a ligand. This kind of encoding has found many applications in drug-discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0563c31d5ac26886ad6caab2d40c06f3
https://doaj.org/article/b80815d56a404d318b8aa6f615e5059f
https://doaj.org/article/b80815d56a404d318b8aa6f615e5059f
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(3)
Flavonoids are secondary metabolites ubiquitously found in plants. Their antioxidant properties make them highly interesting natural compounds to be used in pharmacology. Therefore, unravelling the mechanisms of flavonoids biosynthesis is a current h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb152c43889b9aad81ecb6190c35f8c
https://pubmed.ncbi.nlm.nih.gov/34859558
https://pubmed.ncbi.nlm.nih.gov/34859558
Autor:
Yi Wang, Sébastien Fiorucci, Peihua Jiang, Weiwei Lei, Huabin Zhao, Cédric Bouysset, Robert F. Margolskee, Amanda L Zajac, Jérôme Golebiowski, Carol M. Christensen
Publikováno v:
Chemical Senses
Chemical Senses, Oxford University Press (OUP), 2019, 44 (5), pp.339-347. ⟨10.1093/chemse/bjz024⟩
Chemical Senses, Oxford University Press (OUP), 2019, 44 (5), pp.339-347. ⟨10.1093/chemse/bjz024⟩
Divalent and trivalent salts exhibit a complex taste profile. They are perceived as being astringent/drying, sour, bitter, and metallic. We hypothesized that human bitter-taste receptors may mediate some taste attributes of these salts. Using a cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1843663b99331cc0418bb00b93ec09ec
https://doi.org/10.1093/chemse/bjz024
https://doi.org/10.1093/chemse/bjz024
Autor:
Jérémie Topin, Cédric Bouysset, Jody Pacalon, Yiseul Kim, MeeRa Rhyu, Sébastien Fiorucci, Jérôme Golebiowski
Bitter taste receptors (TAS2Rs) are a poorly understood subgroup of G protein-coupled receptors (GPCRs). The experimental structure of these receptors has yet to be determined, and key-residues controlling their function remain mostly unknown. We des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b48296755feeac68191e4ff03ac5c7
https://doi.org/10.1101/2020.10.23.348706
https://doi.org/10.1101/2020.10.23.348706
Publikováno v:
Food Chemistry
Food Chemistry, Elsevier, 2020, 324, pp.126864. ⟨10.1016/j.foodchem.2020.126864⟩
Food Chemistry, Elsevier, 2020, 324, pp.126864. ⟨10.1016/j.foodchem.2020.126864⟩
Sugar replacement is still an active issue in the food industry. The use of structure-taste relationships remains one of the most rational strategy to expand the chemical space associated to sweet taste. A new machine learning model has been setup ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21173c239e876400b80520997aa430bb
https://hal.univ-cotedazur.fr/hal-02547525
https://hal.univ-cotedazur.fr/hal-02547525
Autor:
Cédric Bouysset, Jérôme Golebiowski, Gabriela Caballero-Vidal, Sébastien Fiorucci, Nicolas Montagné, Hubert Grunig, Emmanuelle Jacquin-Joly
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-58564-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1655. ⟨10.1038/s41598-020-58564-9⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-58564-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1655. ⟨10.1038/s41598-020-58564-9⟩
Odorant receptors expressed at the peripheral olfactory organs are key proteins for animal volatile sensing. Although they determine the odor space of a given species, their functional characterization is a long process and remains limited. To date,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd7ebb9fd5a36043333321ae3177a18
https://hal.archives-ouvertes.fr/hal-02544670
https://hal.archives-ouvertes.fr/hal-02544670
Publikováno v:
Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters, American Chemical Society, 2018, 9 (9), pp.2235-2240. ⟨10.1021/acs.jpclett.8b00633⟩
J Phys Chem Lett
Journal of Physical Chemistry Letters, American Chemical Society, 2018, 9 (9), pp.2235-2240. ⟨10.1021/acs.jpclett.8b00633⟩
J Phys Chem Lett
Predicting the activity of chemicals for a given odorant receptor is a longstanding challenge. Here the activity of 258 chemicals on the human G-protein-coupled odorant receptor (OR)51E1, also known as prostate-specific G-protein-coupled receptor 2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24c7879ee308f39573f29a6025f5576
https://doi.org/10.1021/acs.jpclett.8b00633
https://doi.org/10.1021/acs.jpclett.8b00633