Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sébastien Brûlé"'
Autor:
Mariano Martinez, Anthony Bouillon, Sébastien Brûlé, Bertrand Raynal, Ahmed Haouz, Pedro M. Alzari, Jean-Christophe Barale
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Malaria symptoms are associated with the asexual multiplication of Plasmodium falciparum within human red blood cells (RBCs) and fever peaks coincide with the egress of daughter merozoites following the rupture of the parasitophorous vacuole
Externí odkaz:
https://doaj.org/article/ba0f32637eef4326823e45be733aa725
Autor:
Thierry Mourer, Mennat El Ghalid, Gérard Pehau-Arnaudet, Brice Kauffmann, Antoine Loquet, Sébastien Brûlé, Vitor Cabral, Christophe d’Enfert, Sophie Bachellier-Bassi
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract The human commensal fungus Candida albicans can attach to epithelia or indwelling medical devices and form biofilms, that are highly tolerant to antifungal drugs and can evade the immune response. The cell surface protein Pga59 has been show
Externí odkaz:
https://doaj.org/article/8cd84241961946acb2fee85a8d833f53
Autor:
Yanlei Zhu, Flavio Alvarez, Nicolas Wolff, Ariel Mechaly, Sébastien Brûlé, Benoit Neitthoffer, Sandrine Etienne-Manneville, Ahmed Haouz, Batiste Boëda, Célia Caillet-Saguy
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ-binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains, which is identical to the PBM of SARS-CoV. The latter is involved in the pathogen
Externí odkaz:
https://doaj.org/article/83f9c47b27174efc8db594ca4eb44d6f
Autor:
Bruno Tello Rubio, Florence Bugault, Blandine Baudon, Bertrand Raynal, Sébastien Brûlé, Jean-David Morel, Sarah Saint-Auret, Nicolas Blanchard, Caroline Demangel, Laure Guenin-Macé
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mycolactone is a diffusible lipid toxin produced by Mycobacterium ulcerans, the causative agent of Buruli ulcer disease. Altough bacterially derived mycolactone has been shown to traffic from cutaneous foci of infection to the bloodstream, the mechan
Externí odkaz:
https://doaj.org/article/686671b24ba34cd3a90a370297460600
Autor:
Alexis Voegele, Mirko Sadi, Darragh Patrick O'Brien, Pauline Gehan, Dorothée Raoux‐Barbot, Maryline Davi, Sylviane Hoos, Sébastien Brûlé, Bertrand Raynal, Patrick Weber, Ariel Mechaly, Ahmed Haouz, Nicolas Rodriguez, Patrice Vachette, Dominique Durand, Sébastien Brier, Daniel Ladant, Alexandre Chenal
Publikováno v:
Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)
Abstract The molecular mechanisms and forces involved in the translocation of bacterial toxins into host cells are still a matter of intense research. The adenylate cyclase (CyaA) toxin from Bordetella pertussis displays a unique intoxication pathway
Externí odkaz:
https://doaj.org/article/ab5620c2ceda4fd589efb6c6a8e4c275
Autor:
Clément Madru, Ayten Dizkirici Tekpinar, Sandrine Rosario, Dariusz Czernecki, Sébastien Brûlé, Ludovic Sauguet, Marc Delarue
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250610 (2021)
To stop the COVID-19 pandemic due to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which caused more than 2.5 million deaths to date, new antiviral molecules are urgently needed. The replication of SARS-CoV-2 requires the RNA-depe
Externí odkaz:
https://doaj.org/article/420e08afabc54742ac1f3b295bdff275
Autor:
Pierre Raia, Marta Carroni, Etienne Henry, Gérard Pehau-Arnaudet, Sébastien Brûlé, Pierre Béguin, Ghislaine Henneke, Erik Lindahl, Marc Delarue, Ludovic Sauguet
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000122 (2019)
PolD is an archaeal replicative DNA polymerase (DNAP) made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2). Recently, we reported the individual crystal structures of the DP1 and DP2 catalytic cores, thereb
Externí odkaz:
https://doaj.org/article/ff23331df20647f8a096ed185fd83ce6
Autor:
Adrien A. Blisnick, Ladislav Šimo, Catherine Grillon, Fabienne Fasani, Sébastien Brûlé, Bernard Le Bonniec, Eric Prina, Maud Marsot, Anthony Relmy, Sandra Blaise-Boisseau, Jennifer Richardson, Sarah I. Bonnet
Publikováno v:
Vaccines, Vol 7, Iss 4, p 148 (2019)
Ticks are the most important vectors of pathogens affecting both domestic and wild animals worldwide. Hard tick feeding is a slow process—taking up to several days—and necessitates extended control over the host response. The success of the feedi
Externí odkaz:
https://doaj.org/article/a586b47480ba437eb79bfcd156b9e18b
Autor:
William P. M. Worrall, Jasper B. J. Kamphuis, Julien Stackowicz, Aurélie Mougel, Emilie Mauré, Cyprien Pecalvel, Sébastien Brûlé, Pierre Bruhns, Laurent Guilleminault, Laurent L. Reber
Publikováno v:
Allergy
Allergy, 2022, 77 (6), pp.1903-1906. ⟨10.1111/all.15269⟩
Allergy, 2022, 77 (6), pp.1903-1906. ⟨10.1111/all.15269⟩
International audience; In humans, the high-affinity IgE receptor FcεRI is expressed as a tetramer in mast cells (MCs) and basophils, and as a trimer in additional myeloid cell populations, including monocytes, macrophages, dendritic cells (DCs), an
Autor:
Souheyla Benfrid, Kyu‐Ho Park, Mariano Dellarole, James E Voss, Carole Tamietti, Gérard Pehau‐Arnaudet, Bertrand Raynal, Sébastien Brûlé, Patrick England, Xiaokang Zhang, Anastassia Mikhailova, Milena Hasan, Marie‐Noëlle Ungeheuer, Stéphane Petres, Scott B Biering, Eva Harris, Anavaj Sakuntabhai, Philippe Buchy, Veasna Duong, Philippe Dussart, Fasséli Coulibaly, François Bontems, Félix A Rey, Marie Flamand
Publikováno v:
EMBO Reports
EMBO Reports, 2022, 23 (7), pp.e53600. ⟨10.15252/embr.202153600⟩
EMBO Reports, 2022, 23 (7), pp.e53600. ⟨10.15252/embr.202153600⟩
International audience; The dengue virus nonstructural protein 1 (NS1) is a secreted virulence factor that modulates complement, activates immune cells and alters endothelial barriers. The molecular basis of these events remains incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26614778de3f47f3eade783ba4462ef
https://hal-pasteur.archives-ouvertes.fr/pasteur-03698274/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03698274/document