Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Sébastien, Rodrigue"'
Autor:
Frédéric Grenier, Vincent Baby, Sarah Allard, Simon Lévesque, François Papale, Richard Sullivan, Hannah L. Landecker, Paul G. Higgins, Sébastien Rodrigue, Louis-Patrick Haraoui
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT blaNDM, the most prevalent carbapenemase among carbapenem-resistant Enterobacteriaceae, is thought to have emerged in India, as its initial detection in 2008 was linked to this country, and subsequent retrospective surveys had so far establi
Externí odkaz:
https://doaj.org/article/8ec345d98fb04779b4ced6610b10fed6
Autor:
Antoine Champie, Jean-Christophe Lachance, Anand Sastry, Dominick Matteau, Colton J. Lloyd, Frédéric Grenier, Cameron R. Lamoureux, Simon Jeanneau, Adam M. Feist, Pierre-Étienne Jacques, Bernhard O. Palsson, Sébastien Rodrigue
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Microorganisms with simplified genomes represent interesting cell chassis for systems and synthetic biology. However, genome reduction can lead to undesired traits, such as decreased growth rate and metabolic imbalances. To investigate the i
Externí odkaz:
https://doaj.org/article/04a55e0de4eb4ac2a7d3e89e6f0be8fb
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Bacterial conjugation is a major horizontal gene transfer mechanism. While the functions encoded by many conjugative plasmids have been intensively studied, the contribution of recipient chromosome-encoded genes remains largely unknown. Here
Externí odkaz:
https://doaj.org/article/d41d9ca7d9eb4c2ebd591024ebdf69b8
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTTigecycline is an antibiotic of last resort for infections with carbapenem-resistant Acinetobacter baumannii. Plasmids harboring variants of the tetracycline destructase gene tetX promote rising tigecycline resistance rates. We report the ear
Externí odkaz:
https://doaj.org/article/1757d7bf9f8140f08ddaef607de52ffb
Autor:
Maude Pomerleau, Vincent Charron-Lamoureux, Lucille Léonard, Frédéric Grenier, Sébastien Rodrigue, Pascale B. Beauregard
Publikováno v:
mSystems, Vol 9, Iss 2 (2024)
ABSTRACTRoot-associated microorganisms play an important role in plant health, such as plant growth-promoting rhizobacteria (PGPR) from the Bacillus and Pseudomonas genera. Although bacterial consortia including these two genera would represent a pro
Externí odkaz:
https://doaj.org/article/f32ec2dff0f444ecab509c43e8caf2cb
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Mesoplasma florum is an emerging model organism for systems and synthetic biology due to its small genome (∼800 kb) and fast growth rate. While M. florum was isolated and first described almost 40 years ago, many important aspects of its biology ha
Externí odkaz:
https://doaj.org/article/87985913c305490887cdc29348570f00
Enabling low-cost and robust essentiality studies with high-throughput transposon mutagenesis (HTTM)
Autor:
Antoine Champie, Amélie De Grandmaison, Simon Jeanneau, Frédéric Grenier, Pierre-Étienne Jacques, Sébastien Rodrigue
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Transposon-insertion sequencing (TIS) methods couple high density transposon mutagenesis with next-generation sequencing and are commonly used to identify essential or important genes in bacteria. However, this approach can be work-intensive and some
Externí odkaz:
https://doaj.org/article/f0cea8d18a6348a69e127b7d13a13d3f
Autor:
Kevin Neil, Nancy Allard, Patricia Roy, Frédéric Grenier, Alfredo Menendez, Vincent Burrus, Sébastien Rodrigue
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp 1-12 (2021)
Abstract Antibiotic resistance threatens our ability to treat infectious diseases, spurring interest in alternative antimicrobial technologies. The use of bacterial conjugation to deliver CRISPR‐cas systems programmed to precisely eliminate antibio
Externí odkaz:
https://doaj.org/article/c9ddf6574182493ea5f2edf2a1f7117a
Autor:
Jean‐Christophe Lachance, Dominick Matteau, Joëlle Brodeur, Colton J Lloyd, Nathan Mih, Zachary A King, Thomas F Knight, Adam M Feist, Jonathan M Monk, Bernhard O Palsson, Pierre‐Étienne Jacques, Sébastien Rodrigue
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 7, Pp 1-20 (2021)
Abstract Mesoplasma florum, a fast‐growing near‐minimal organism, is a compelling model to explore rational genome designs. Using sequence and structural homology, the set of metabolic functions its genome encodes was identified, allowing the rec
Externí odkaz:
https://doaj.org/article/ffd50eb1a2234bef84adfb826296e9f3
Autor:
Guillaume Millette, David Lalonde Séguin, Charles Isabelle, Suzanne Chamberland, Jean-François Lucier, Sébastien Rodrigue, André M. Cantin, François Malouin
Publikováno v:
Antibiotics, Vol 12, Iss 6, p 1069 (2023)
Prototypic Staphylococcus aureus and their small-colony variants (SCVs) are predominant in cystic fibrosis (CF), but the interdependence of these phenotypes is poorly understood. We characterized S. aureus isolates from adult CF patients over several
Externí odkaz:
https://doaj.org/article/2ae385d95a6e4b7182b92b0258094ba3