Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sébastien, Marion"'
Autor:
William C. Wetsel, Jean-Martin Beaulieu, Valentina Ghisi, Ivan O. Medvedev, Sébastien Marion, Robert J. Lefkowitz, Tatyana D. Sotnikova, Marc G. Caron, Ramona M. Rodriguiz, Raul R. Gainetdinov
Publikováno v:
Cell. 132(1):125-136
Besides their role in desensitization, beta-arrestin 1 and 2 promote the formation of signaling complexes allowing G protein-coupled receptors (GPCR) to signal independently from G proteins. Here we show that lithium, a pharmacological agent used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a167903622244c5b65945edbd7904ab6
Autor:
H. Kim Lyerly, Lauren K. Rochelle, Larry S. Barak, Marc G. Caron, Sébastien Marion, Joshua C. Snyder
Publikováno v:
Journal of cell science. 128(6)
Embryonic development and adult tissue homeostasis require precise information exchange between cells and their microenvironment to coordinate cell behavior. A specialized class of ultra-long actin-rich filopodia, termed cytonemes, provides one mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce72bd98d07007fd054c13261657fbd
https://pubmed.ncbi.nlm.nih.gov/25653388
https://pubmed.ncbi.nlm.nih.gov/25653388
Autor:
Diane Ramires Fernandes, Michel Cyr, Caroline Batista Franco Ribeiro, Cristina Martins-Silva, Natalia Rodrigues Carvalho, Carlos Chávez-Olórtegui, Lucimar T. Ferreira, Marco A. M. Prado, Vania F. Prado, Sébastien Marion, Janaina Koenen
Publikováno v:
Brain Research. 1119:1-12
We isolated from a brain library a cDNA encoding an isoform of rat CED-6 that has not been previously described. This transcript results from alternative splicing of the ced-6 gene present on chromosome 9. We expressed this isoform as his-tagged prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2986859fe20c940dc42218d1e0d3cd0
https://doi.org/10.1016/j.brainres.2006.08.064
https://doi.org/10.1016/j.brainres.2006.08.064
Autor:
Elodie Kara, Pascale Crépieux, Florian Guillou, Vincent Piketty, Nadine Martinat, Sébastien Marion, Eric Reiter
Publikováno v:
Journal of Endocrinology. 190:341-350
FSH-receptor (FSH-R) signaling is regulated by agonist-induced desensitization and internalization. It has been shown, in a variety of overexpression systems, that G protein-coupled receptor kinases (GRKs) phosphorylate the activated FSH-R, promote b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4d4eb97463c823e01353cad0ac84d7
https://doi.org/10.1677/joe.1.06857
https://doi.org/10.1677/joe.1.06857
Publikováno v:
Journal of Biological Chemistry. 281:2932-2938
beta-Arrestins have been shown to inhibit competitively G protein-dependent signaling and to mediate endocytosis for many of the hundreds of nonvisual rhodopsin family G protein-coupled receptors (GPCR). An open question of fundamental importance con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e38bec1399ebef979de859f58fce1e
https://doi.org/10.1074/jbc.m508074200
https://doi.org/10.1074/jbc.m508074200
Autor:
Elodie Kara, Nadine Martinat, Eric Reiter, Charlotte Lécureuil, Florian Guillou, Dominique Royere, Vincent Piketty, Sébastien Marion, Pascale Crepieux
Publikováno v:
Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2004, 10 (5), pp.449-469
Current Pharmaceutical Design, Bentham Science Publishers, 2004, 10 (5), pp.449-469
The testis is devoted to two important tasks: haploid cell production and sexual steroid synthesis. A number of highly sophisticated and unique strategies operate during spermatogenesis, a process crucial for reproduction, heredity and evolution. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88f2440053dda60ef348c816c619b9d
https://doi.org/10.2174/1381612043453270
https://doi.org/10.2174/1381612043453270
Publikováno v:
Journal of Biological Chemistry. 279:2945-2954
The 5-hydroxytryptamine2c receptor (5-HT2cR) is subjected to RNA editing, in the second intracellular loop, generating 14 different isoforms in human brain. This post-transcriptional event markedly alters the signaling properties of the receptor by r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c023258e4091f7ad1751cbfa20687604
https://doi.org/10.1074/jbc.m308742200
https://doi.org/10.1074/jbc.m308742200
Publikováno v:
Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, Elsevier, 2002, 399 (2), pp.245-250
Archives of Biochemistry and Biophysics, Elsevier, 2002, 399 (2), pp.245-250
The cellular adhesion status and the exposure to soluble growth factors both contribute to mitogen-activated protein (MAP) kinase activation. To date, however, whether mitogens acting through G-protein-coupled receptors (GPCRs) need cell adhesion to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb13d9fe4dca74d55c818adf6a8753be
https://doi.org/10.1006/abbi.2002.2773
https://doi.org/10.1006/abbi.2002.2773
Autor:
Sébastien Marion, F. Robert, Carine Troispoux, Pascale Crépieux, Florian Guillou, Nadine Martinat, Eric Reiter
Publikováno v:
Biology of Reproduction. 66:70-76
The FSH receptor (FSH-R) is a member of the rhodopsin-like subfamily of G protein-coupled receptors that undergoes homologous desensitization upon agonist stimulation. In immortalized cell lines overexpressing the FSH-R, G protein-coupled receptor ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9412a9cd13a5b420f262d3828d49fd06
https://doi.org/10.1095/biolreprod66.1.70
https://doi.org/10.1095/biolreprod66.1.70
Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein
Autor:
Raul R. Gainetdinov, Jean-Martin Beaulieu, Sean M. Peterson, Sébastien Marion, Nikhil M. Urs, Tatyana D. Sotnikova, Marc G. Caron
Publikováno v:
The Journal of biological chemistry. 289(17)
Striatal dopamine D2 receptor (D2R) relies upon G protein- and β-arrestin-dependent signaling pathways to convey its action on motor control and behavior. Considering that D2R activation inhibits Akt in the striatum and that huntingtin physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d425a6df6f26c6226cd23831c4a64d5
https://pubmed.ncbi.nlm.nih.gov/24619418
https://pubmed.ncbi.nlm.nih.gov/24619418