Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sébastien, Flajollet"'
Autor:
Sébastien Flajollet, Christophe Rachez, Maheul Ploton, Céline Schulz, Rozenn Gallais, Raphaël Métivier, Michal Pawlak, Aymeric Leray, Al Amine Issulahi, Laurent Héliot, Bart Staels, Gilles Salbert, Philippe Lefebvre
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64880 (2013)
Nuclear all-trans retinoic acid receptors (RARs) initiate early transcriptional events which engage pluripotent cells to differentiate into specific lineages. RAR-controlled transactivation depends mostly on agonist-induced structural transitions in
Externí odkaz:
https://doaj.org/article/65662d84c5e14954949695af67b93e71
Autor:
Sébastien Flajollet, Tian V Tian, Ludovic Huot, Nathalie Tomavo, Anne Flourens, Muriel Holder-Espinasse, Marion Le Jeune, Patrick Dumont, David Hot, Frédéric Mallein-Gerin, Martine Duterque-Coquillaud
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48656 (2012)
In monolayer culture, primary articular chondrocytes have an intrinsic tendency to lose their phenotype during expansion. The molecular events underlying this chondrocyte dedifferentiation are still largely unknown. Several transcription factors are
Externí odkaz:
https://doaj.org/article/193f01834d3d47558dd9acec6a27a85f
Autor:
Isabelle Poras, Philippe Moreau, Samuel Valable, Stine Skov Jensen, Edgardo D. Carosella, Soldano Ferrone, Layale Yaghi, Isabela J. Wastowski, Bjarne Winther Kristensen, Emmanuèle Lechapt-Zalcman, João T Pancoto, Myriam Bernaudin, Eduardo Antônio Donadi, Carlos Gilberto Carlotti, Sébastien Flajollet, Renata T Simões
Publikováno v:
American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2013, 182 (2), pp.540-552. ⟨10.1016/j.ajpath.2012.10.021⟩
American Journal of Pathology, 2013, 182 (2), pp.540-552. ⟨10.1016/j.ajpath.2012.10.021⟩
American Journal of Pathology, American Society for Investigative Pathology, 2013, 182 (2), pp.540-552. ⟨10.1016/j.ajpath.2012.10.021⟩
American Journal of Pathology, 2013, 182 (2), pp.540-552. ⟨10.1016/j.ajpath.2012.10.021⟩
Human leukocyte antigen-G (HLA-G) is a nonclassical major histocompatibility complex (MHC) class I molecule involved in immune tolerance processes, playing an important role in the maintenance of the semi-allogeneic fetus. Although HLA-G expression i
Autor:
E. Perrier-Groult, Karim Boumediene, M.-C. Ronzière, Hanane Chajra, Anne-Marie Freyria, Philippe Galéra, S. Claus, Magali Demoor, Frédéric Mallein-Gerin, Odile Damour, Sébastien Flajollet, Florence Legendre, Tian V. Tian, C. Bougault, E. Aubert-Foucher, David Ollitrault, Martine Duterque-Coquillaud
Publikováno v:
IRBM. 32:95-98
Resume Le projet PROMOCART (2007–2010) a ete retenu suite a l’appel 2006 ANR-TecSan. Il a ete conduit par le laboratoire « Biologie et ingenierie du cartilage » (Lyon) en partenariat avec les laboratoires « Matrice extracellulaire et pathologi
Publikováno v:
Journal of Cellular and Molecular Medicine
Human leucocyte antigen-G (HLA-G) plays a key role in maternal-foetal tolerance and allotransplantation acceptance and is also implicated in tumour escape from the immune system. The modulation of HLA-G expression can prove to be very important to th
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2007, 270 (1-2), pp.23. ⟨10.1016/j.mce.2007.02.004⟩
Molecular and Cellular Endocrinology, Elsevier, 2007, 270 (1-2), pp.23. ⟨10.1016/j.mce.2007.02.004⟩
Retinoic acid receptors (RARs) activate transcription by recruiting coactivator complexes such as histone acetyltransferases (HAT) and the mediator complex, to increase chromatin accessibility by general transcription factors and to promote transcrip
Autor:
Tian V. Tian, Y. De Launoit, Xavier Leroy, Ludovic Huot, Nathalie Tomavo, Martine Duterque-Coquillaud, Anne Flourens, Sébastien Flajollet, Edith Bonnelye, David Hot
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2014, 33 (17), pp.2204-2214. ⟨10.1038/onc.2013.176⟩
Oncogene, 2014, 33 (17), pp.2204-2214. ⟨10.1038/onc.2013.176⟩
Oncogene, Nature Publishing Group, 2014, 33 (17), pp.2204-2214. ⟨10.1038/onc.2013.176⟩
Oncogene, 2014, 33 (17), pp.2204-2214. ⟨10.1038/onc.2013.176⟩
International audience; Prostate cancer (PCa) is one of the major public health problems in Western countries. Recently, the TMPRSS2:ERG gene fusion, which results in the aberrant expression of the transcription factor ERG, has been shown to be the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d576f6a8be17c3a0773fdc727480c1
https://hal.archives-ouvertes.fr/hal-02353391
https://hal.archives-ouvertes.fr/hal-02353391
Publikováno v:
Hormone molecular biology and clinical investigation. 14(3)
Vitamin A, ingested either as retinol or β-carotene from animal- or plant-derived foods respectively, is a nutrient essential for many biological functions such as embryonic development, vision, immune response, tissue remodeling, and metabolism. It
Autor:
Raphaël Métivier, Bart Staels, Christophe Rachez, Céline Schulz, Aymeric Leray, Maheul Ploton, Philippe Lefebvre, Rozenn Gallais, Al Amine Issulahi, Michał Pawlak, Gilles Salbert, Sébastien Flajollet, Laurent Héliot
Publikováno v:
PLoS ONE
PLoS ONE, 2013, 8 (6), pp.e64880. ⟨10.1371/journal.pone.0064880⟩
PLoS ONE, Vol 8, Iss 6, p e64880 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (6), pp.e64880. ⟨10.1371/journal.pone.0064880⟩
PLoS ONE, 2013, 8 (6), pp.e64880. ⟨10.1371/journal.pone.0064880⟩
PLoS ONE, Vol 8, Iss 6, p e64880 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (6), pp.e64880. ⟨10.1371/journal.pone.0064880⟩
International audience; Nuclear all-trans retinoic acid receptors (RARs) initiate early transcriptional events which engage pluripotent cells to differentiate into specific lineages. RAR-controlled transactivation depends mostly on agonist-induced st
Autor:
W. David Wilson, Chad E. Stephens, Martine Duterque-Coquillaud, Arvind Kumar, Paul Peixoto, Sabine Depauw, David W. Boykin, Marie-Hélène David-Cordonnier, Raja Nhili, Xavier Dezitter, Manoj Munde, Sébastien Flajollet, Abdelbasset A. Farahat, Mohamed A. Ismail
Publikováno v:
Nucleic Acids Research
Direct modulation of gene expression by targeting oncogenic transcription factors is a new area of research for cancer treatment. ERG, an ETS-family transcription factor, is commonly over-expressed or translocated in leukaemia and prostate carcinoma.