Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sébastien, Denanglaire"'
Autor:
Marie Le Moine, Abdulkader Azouz, Guillem Sanchez Sanchez, Solange Dejolier, Muriel Nguyen, Séverine Thomas, Valdrin Shala, Hacene Dreidi, Sébastien Denanglaire, Frédérick Libert, David Vermijlen, Fabienne Andris, Stanislas Goriely
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112876- (2023)
Summary: The co-inhibitory programmed death (PD)-1 signaling pathway plays a major role in the context of tumor-specific T cell responses. Conversely, it also contributes to the maintenance of peripheral tolerance, as patients receiving anti-PD-1 tre
Externí odkaz:
https://doaj.org/article/b082a4b6d11f4acfb5dc137c34148778
Autor:
Anouk Lepez, Tiphène Pirnay, Sébastien Denanglaire, David Perez-Morga, Marjorie Vermeersch, Oberdan Leo, Fabienne Andris
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells is still controversial. Using both in vitro and in vivo model
Externí odkaz:
https://doaj.org/article/9c385a8aea9048439529ca4cda5d6ca6
Autor:
Charlotte Bisilliat Donnet, Valérie Acolty, Abdulkader Azouz, Anaëlle Taquin, Coralie Henin, Sarah Trusso Cafarello, Sébastien Denanglaire, Massimiliano Mazzone, Guillaume Oldenhove, Oberdan Leo, Stanislas Goriely, Muriel Moser
Publikováno v:
Cancer Immunology Research. 11:339-350
The prolyl hydroxylase domain/hypoxia-inducible factor (PHD/HIF) pathway has been implicated in a wide range of immune and inflammatory processes, including in the oxygen-deprived tumor microenvironment. To examine the effect of HIF stabilization in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dccfa9f278b384b6d13668bd6d777e
https://doi.org/10.1158/2326-6066.cir-22-0099
https://doi.org/10.1158/2326-6066.cir-22-0099
Autor:
Hind Hussein, Sébastien Denanglaire, Frédéric Van Gool, Abdulkader Azouz, Yousra Ajouaou, Hana El-Khatib, Guillaume Oldenhove, Oberdan Leo, Fabienne Andris
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
RORγt-expressing Tregs form a specialized subset of intestinal CD4+ Foxp3+ cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota. Recently, c-Maf emerged as a critical factor in the regulation of RORγt expressio
Externí odkaz:
https://doaj.org/article/5b6f4b76b978471a84b84521bf3b3619
Autor:
Muriel Moser, Stanislas Goriely, Oberdan Leo, Guillaume Oldenhove, Massimiliano Mazzone, Sébastien Denanglaire, Sarah Trusso Cafarello, Coralie Henin, Anaëlle Taquin, Abdulkader Azouz, Valérie Acolty, Charlotte Bisilliat Donnet
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfa827d3f3114233fe60e76655e2953
https://doi.org/10.1158/2326-6066.22546475.v1
https://doi.org/10.1158/2326-6066.22546475.v1
Autor:
Muriel Moser, Stanislas Goriely, Oberdan Leo, Guillaume Oldenhove, Massimiliano Mazzone, Sébastien Denanglaire, Sarah Trusso Cafarello, Coralie Henin, Anaëlle Taquin, Abdulkader Azouz, Valérie Acolty, Charlotte Bisilliat Donnet
The prolyl hydroxylase domain/hypoxia-inducible factor (PHD/HIF) pathway has been implicated in a wide range of immune and inflammatory processes, including in the oxygen-deprived tumor microenvironment. To examine the effect of HIF stabilization in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a09ca2ad50144785e7831fa029ee3bb
https://doi.org/10.1158/2326-6066.c.6551183.v1
https://doi.org/10.1158/2326-6066.c.6551183.v1
Cyclophosphamide treatment regulates the balance of functional/exhausted tumor-specific CD8+ T cells
Autor:
Aurélie Hanoteau, Coralie Henin, David Svec, Charlotte Bisilliat Donnet, Sébastien Denanglaire, Didier Colau, Pedro Romero, Oberdan Leo, Benoit Van den Eynde, Muriel Moser
Publikováno v:
OncoImmunology, Vol 6, Iss 8 (2017)
An important question is how chemotherapy may (re-)activate tumor-specific immunity. In this study, we provide a phenotypic, functional and genomic analysis of tumor-specific CD8+ T cells in tumor (P815)-bearing mice, treated or not with cyclophospha
Externí odkaz:
https://doaj.org/article/c8345ee694324e43988a73ec92e52dc0
Autor:
Fabienne Andris, Sébastien Denanglaire, Maelle Anciaux, Mélanie Hercor, Hind Hussein, Oberdan Leo
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Follicular helper T cells (Tfh) have been identified as the primary cell subpopulation regulating B cell responses in germinal centers, thus supporting high-affinity antibody production. Among the transcription factors orchestrating Tfh cell differen
Externí odkaz:
https://doaj.org/article/d750791585f340e597518480782efe4a
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/140990b8da46449e892cd2eec15d5ad9
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84415 (2013)
Follicular T helper cells (Tfh) are crucial for effective antibody responses and long term T cell-dependent humoral immunity. Although many studies are devoted to this novel T helper cell population, the molecular mechanisms governing Tfh cell differ
Externí odkaz:
https://doaj.org/article/82210bf8720241069b6cf2bc9bbd779a