Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Séan P. Kennelly"'
Autor:
Adam H. Dyer, Helena Dolphin, Antoinette O’Connor, Laura Morrison, Gavin Sedgwick, Conor Young, Emily Killeen, Conal Gallagher, Aoife McFeely, Eimear Connolly, Naomi Davey, Paul Claffey, Paddy Doyle, Shane Lyons, Christine Gaffney, Ruth Ennis, Cathy McHale, Jasmine Joseph, Graham Knight, Emmet Kelly, Cliona O’Farrelly, Aoife Fallon, Sean O’Dowd, Nollaig M. Bourke, Sean P. Kennelly
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Plasma p-tau217 has emerged as the most promising blood-based marker (BBM) for the detection of Alzheimer Disease (AD) pathology, yet few studies have evaluated plasma p-tau217 performance in memory clinic settings. We examined th
Externí odkaz:
https://doaj.org/article/0e00f717357c41d39551a030163c489b
Publikováno v:
International journal of geriatric psychiatry. 37(8)
Aducanumab is a monoclonal antibody which has recently been licenced for use by the food and drug administration for treatment of patients with mild cognitive impairment due to Alzheimer's disease (AD) or mild AD dementia. Appropriate use criteria (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9e40d41522b3e2699c7b794789ccb5
https://pubmed.ncbi.nlm.nih.gov/35861223
https://pubmed.ncbi.nlm.nih.gov/35861223
Autor:
Laura Morrison, Adam H. Dyer, Helena Dolphin, Isabella Batten, Conor Reddy, Matthew Widdowson, Conor P. Woods, James Gibney, Nollaig M. Bourke, Sean P. Kennelly
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100862- (2024)
Midlife cardiovascular risk factors such as Type 2 Diabetes (T2DM) and obesity are associated with the later development of cognitive impairment and dementia. Systemic inflammation is postulated as a crucial mechanism, yet there are few studies exami
Externí odkaz:
https://doaj.org/article/f8306b991c3b4f9d803209c20cf33e90
Publikováno v:
Sensors, Vol 24, Iss 17, p 5550 (2024)
Gait speed is increasingly recognized as an important health indicator. However, gait analysis in clinical settings often encounters inconsistencies due to methodological variability and resource constraints. To address these challenges, GaitKeeper u
Externí odkaz:
https://doaj.org/article/6bc94227d33b4abca7e3c792eb2b9def
Autor:
Laura Morrison, Adam H. Dyer, Helena Dolphin, Isabelle Killane, Nollaig M. Bourke, Matthew Widdowson, Conor P. Woods, James Gibney, Richard B. Reilly, Sean P. Kennelly
Publikováno v:
Sensors, Vol 24, Iss 12, p 3903 (2024)
Midlife risk factors such as type 2 diabetes mellitus (T2DM) confer a significantly increased risk of cognitive impairment in later life with executive function, memory, and attention domains often affected first. Spatiotemporal gait characteristics
Externí odkaz:
https://doaj.org/article/16cf272cc77e44509db8c53eb78b646e
Autor:
Tim Dukelow, Philip Vassilev, Erin Grace Lawrence, Liron Jacobson, Ivan Koychev, Kinan Muhammed, Sean P. Kennelly
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
Modifiable risk factors for dementia remain prevalent in Ireland. A detailed examination of barriers to risk reduction behaviours in an Irish context has heretofore been lacking. Many existing studies examining barriers to brain health behaviours fai
Externí odkaz:
https://doaj.org/article/d39b1b62439c4c0887ee15c2a337982b
Autor:
Heike C. Hawerkamp, Adam H. Dyer, Neha D. Patil, Matt McElheron, Niamh O’Dowd, Laura O’Doherty, Aisling Ui Mhaonaigh, Angel M. George, Aisling M. O’Halloran, Conor Reddy, Rose Anne Kenny, Mark A. Little, Ignacio Martin-Loeches, Colm Bergin, Sean P. Kennelly, Seamas C. Donnelly, Nollaig M. Bourke, Aideen Long, Jacklyn Sui, Derek G. Doherty, Niall Conlon, Cliona Ni Cheallaigh, Padraic G. Fallon
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic, are remarkably variable ranging from asymptomatic infection to severe pneumonia and death. One of the key drivers of this variability is differing trajectories in t
Externí odkaz:
https://doaj.org/article/55a248964b0f4c47b23b9c07a22af0be
Autor:
Tim Dukelow, Erin Grace Lawrence, Liron Jacobson, Philip Vassilev, Ivan Koychev, Kinan Muhammed, Sean P. Kennelly
Publikováno v:
Frontiers in Psychology, Vol 13 (2023)
Up to 40% of dementias globally are attributable to modifiable risk factors. Many existing studies examining attitudes to brain health are limited by a failure to consider a range of pertinent risk factors and associated barriers to protective behavi
Externí odkaz:
https://doaj.org/article/a4ee2112629d459e96d1149dde83b173
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background With the evolving knowledge on hearing as a potentially modifiable mid-life risk factor for dementia, identification of people at risk becomes increasingly important. People with mild cognitive impairment (MCI) presenting to speci
Externí odkaz:
https://doaj.org/article/4272a47f89cd473ab782fbc00674d41e
Autor:
Irina Kinchin, Iracema Leroi, Sean P. Kennelly, Slavica Kochovska, Conor Brady, Deborah Fitzhenry, Cathy McHale, Philip Kinghorn, Joanna Coast
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionEconomic evaluation currently focuses almost exclusively on the maximization of health, using the Quality-Adjusted Life-Year (QALY) framework with instruments such as the EQ-5D, with a limited number of health-focused dimensions providing
Externí odkaz:
https://doaj.org/article/808136d21a3a45f182b56bbeae9dfb26