Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sævar Ingthorsson"'
Autor:
Jon Petur Joelsson, Arni Asbjarnarson, Snaevar Sigurdsson, Jennifer Kricker, Bryndis Valdimarsdottir, Holmfridur Thorarinsdottir, Eir Starradottir, Thorarinn Gudjonsson, Saevar Ingthorsson, Sigurbergur Karason
Publikováno v:
Laboratory Animal Research, Vol 38, Iss 1, Pp 1-15 (2022)
Abstract Background Mechanical ventilation is a life-saving therapy for critically ill patients, providing rest to the respiratory muscles and facilitating gas exchange in the lungs. Ventilator-induced lung injury (VILI) is an unfortunate side effect
Externí odkaz:
https://doaj.org/article/72de43d601f14dc88678df500648563b
Autor:
Jon Petur Joelsson, Saevar Ingthorsson, Jennifer Kricker, Thorarinn Gudjonsson, Sigurbergur Karason
Publikováno v:
Laboratory Animal Research, Vol 37, Iss 1, Pp 1-11 (2021)
Abstract Ventilator-induced lung injury (VILI) is a serious acute injury to the lung tissue that can develop during mechanical ventilation of patients. Due to the mechanical strain of ventilation, damage can occur in the bronchiolar and alveolar epit
Externí odkaz:
https://doaj.org/article/b90051c7044b44fb9080169462e24f79
Autor:
Alexander Schepsky, Gunnhildur Asta Traustadottir, Jon Petur Joelsson, Sævar Ingthorsson, Jennifer Kricker, Jon Thor Bergthorsson, Arni Asbjarnarson, Thorkell Gudjonsson, Nina Nupponen, Ana Slipicevic, Fredrik Lehmann, Thorarinn Gudjonsson
Publikováno v:
Cancer Medicine, Vol 9, Iss 18, Pp 6726-6738 (2020)
Abstract Melphalan flufenamide (hereinafter referred to as “melflufen”) is a peptide‐conjugated drug currently in phase 3 trials for the treatment of relapsed or refractory multiple myeloma. Due to its lipophilic nature, it readily enters cells
Externí odkaz:
https://doaj.org/article/5b8204561d5640db964aa4eb74a5b510
Autor:
Jon Petur Joelsson, Jennifer A. Kricker, Ari J. Arason, Snaevar Sigurdsson, Bryndis Valdimarsdottir, Fridrik Runar Gardarsson, Clive P. Page, Fredrik Lehmann, Thorarinn Gudjonsson, Saevar Ingthorsson
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung diseases that are commonly treated with A
Externí odkaz:
https://doaj.org/article/68af876a3a5d4feaab0da207655852e8
Publikováno v:
Cancers, Vol 14, Iss 21, p 5209 (2022)
The human breast gland is a unique organ as most of its development occurs postnatally between menarche and menopause, a period ranging from 30 to 40 years. During this period, the monthly menstruation cycle drives the mammary gland through phases of
Externí odkaz:
https://doaj.org/article/e56da40cdfba456cba8fb8acdf18d70a
Autor:
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity
Externí odkaz:
https://doaj.org/article/c8da4be92fa246189c8660fe3fd024d1
Autor:
Zhiqian Yi, Yixi Su, Maonian Xu, Andreas Bergmann, Saevar Ingthorsson, Ottar Rolfsson, Kourosh Salehi-Ashtiani, Sigurdur Brynjolfsson, Weiqi Fu
Publikováno v:
Marine Drugs, Vol 16, Iss 8, p 272 (2018)
Diatoms are a major group of unicellular algae that are rich in lipids and carotenoids. However, sustained research efforts are needed to improve the strain performance for high product yields towards commercialization. In this study, we generated a
Externí odkaz:
https://doaj.org/article/401ee90898b34b968a9af2f4f03f9625
Autor:
Ari Jon Arason, Hulda R Jonsdottir, Skarphedinn Halldorsson, Berglind Eva Benediktsdottir, Jon Thor Bergthorsson, Saevar Ingthorsson, Olafur Baldursson, Satrajit Sinha, Thorarinn Gudjonsson, Magnus K Magnusson
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88683 (2014)
The upper airways are lined with a pseudostratified bronchial epithelium that forms a barrier against unwanted substances in breathing air. The transcription factor p63, which is important for stratification of skin epithelium, has been shown to be e
Externí odkaz:
https://doaj.org/article/7ee2d0d85e3c4f28814a8743b7be37bd
Autor:
Valgardur Sigurdsson, Saevar Ingthorsson, Bylgja Hilmarsdottir, Sigrun M Gustafsdottir, Sigridur Rut Franzdottir, Ari Jon Arason, Eirikur Steingrimsson, Magnus K Magnusson, Thorarinn Gudjonsson
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60798 (2013)
Branching morphogenesis is a mechanism used by many species for organogenesis and tissue maintenance. Receptor tyrosine kinases (RTKs), including epidermal growth factor receptor (EGFR) and the sprouty protein family are believed to be critical regul
Externí odkaz:
https://doaj.org/article/7a8e2ff643864228badca2336c49eecb
Autor:
Bryndis Valdimarsdottir, Saevar Ingthorsson, Jennifer A. Kricker, Ari Jon Arason, Snaevar Sigurdsson, Fridrik Runar Gardarsson, Clive P. Page, Thorarinn Gudjonsson, Jon Petur Joelsson, Fredrik Lehmann
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Respiratory Research
Respiratory Research
Publisher's version (útgefin grein)
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease