Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sára, Zsigrai"'
Autor:
Krisztina A. Szigeti, Alexandra Kalmár, Orsolya Galamb, Gábor Valcz, Barbara K. Barták, Zsófia B. Nagy, Sára Zsigrai, Ildikó Felletár, Árpád V. Patai, Tamás Micsik, Márton Papp, Eszter Márkus, Zsolt Tulassay, Peter Igaz, István Takács, Béla Molnár
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Hypomethylation of long interspersed nuclear element 1 (LINE-1) is characteristic of various cancer types, including colorectal cancer (CRC). Malfunction of several factors or alteration of methyl-donor molecules’ (folic acid an
Externí odkaz:
https://doaj.org/article/a3cba87d0ca445b29b049f95ed79730e
Autor:
William J. Kothalawala, Barbara K. Barták, Zsófia B. Nagy, Sára Zsigrai, Krisztina A. Szigeti, Gábor Valcz, István Takács, Alexandra Kalmár, Béla Molnár
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
In recent years, the evolution of the molecular biological technical background led to the widespread application of single-cell sequencing, a versatile tool particularly useful in the investigation of tumor heterogeneity. Even 10 years ago the compr
Externí odkaz:
https://doaj.org/article/fc8343cda35a4f69b2dafbeb2dcdc966
Autor:
Gábor Valcz, Edit I. Buzás, Ágnes Kittel, Tibor Krenács, Tamás Visnovitz, Sándor Spisák, György Török, László Homolya, Sára Zsigrai, Gábor Kiszler, Géza Antalffy, Krisztina Pálóczi, Zoltán Szállási, Vanessza Szabó, Anna Sebestyén, Norbert Solymosi, Alexandra Kalmár, Kristóf Dede, Péter Lőrincz, Zsolt Tulassay, Péter Igaz, Béla Molnár
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Small extracellular vesicles (EVs) are membrane enclosed structures that are usually released from cells upon exocytosis of multivesicular bodies (MVBs) as a collection of separate, free EVs. In this study, we analysed paraffin embedded sections of a
Externí odkaz:
https://doaj.org/article/00068c82b34b4d0f9a0b2d8080de71f7
Autor:
Alexandra Kalmár, Orsolya Galamb, Gitta Szabó, Orsolya Pipek, Anna Medgyes-Horváth, Barbara K. Barták, Zsófia B. Nagy, Krisztina A. Szigeti, Sára Zsigrai, István Csabai, Péter Igaz, Béla Molnár, István Takács
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 907
Volume 15
Issue 3
Pages: 907
Analysis of circulating cell-free DNA (cfDNA) of colorectal adenoma (AD) and cancer (CRC) patients provides a minimally invasive approach that is able to explore genetic alterations. It is unknown whether there are specific genetic variants that coul
Autor:
Sára Zsigrai, Alexandra Kalmár, Zsófia B. Nagy, Barbara K. Barták, Gábor Valcz, Krisztina A. Szigeti, Orsolya Galamb, Titanilla Dankó, Anna Sebestyén, Gábor Barna, Vanessza Szabó, Orsolya Pipek, Anna Medgyes-Horváth, István Csabai, Zsolt Tulassay, Péter Igaz, István Takács, Béla Molnár
Publikováno v:
Cells, Vol 9, Iss 8, p 1864 (2020)
Global DNA hypomethylation is a characteristic feature of colorectal carcinoma (CRC). The tumor inhibitory effect of S-adenosylmethionine (SAM) methyl donor has been described in certain cancers including CRC. However, the molecular impact of SAM tre
Externí odkaz:
https://doaj.org/article/6ed380cf3d6b4ef4974e97eea8289f16
Autor:
Krisztina A Szigeti, Barbara K Barták, Zsófia B Nagy, Sára Zsigrai, Márton Papp, Eszter Márkus, Peter Igaz, István Takács, Béla Molnár, Alexandra Kalmár
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11608
Long interspersed nuclear element 1 (LINE-1) bisulfite pyrosequencing is a widely used technique for genome-wide methylation analyses. We aimed to investigate the effects of experimental and biological factors on its results to improve the comparabil
Autor:
Anna Sebestyén, Zsolt Tulassay, Gábor Barna, Sára Zsigrai, Tibor Krenács, István Csabai, Alexandra Kalmár, Csilla Kriston, Zsófia Brigitta Nagy, Barbara Kinga Barták, Peter Igaz, Béla Molnár, Orsolya Galamb, Titanilla Dankó, Barnabás Wichmann, Péter Hollósi, István Fűri
Publikováno v:
Pathology Oncology Research
Up-regulation of the long non-coding RNA LINC00152 can contribute to cancer development, proliferation and invasion, including colorectal cancer, however, its mechanism of action in colorectal carcinogenesis and progression is only insufficiently und
Autor:
Sára Zsigrai, Katalin Leiszter, Alexandra Kalmár, Zsolt Tulassay, Peter Igaz, Béla Molnár, Magdolna Dank, Gábor Valcz, Barbara Kinga Barták, Zsolt Liposits, Krisztina Andrea Szigeti, Zsófia Nagy, Orsolya Galamb
Publikováno v:
Orvosi Hetilap. 161:532-543
Absztrakt: A colorectalis carcinoma (CRC) az egyik leggyakrabban előforduló daganatos megbetegedés világszerte. A sporadikus vastagbélrák incidenciája ötvenéves kor alatt alacsonyabb, majd az életkor előrehaladtával nő, továbbá jellegz
Autor:
Barbara Kinga Barták, Tamás Fodor, Alexandra Kalmár, Zsófia Brigitta Nagy, Sára Zsigrai, Krisztina Andrea Szigeti, Gábor Valcz, Péter Igaz, Magdolna Dank, István Takács, Béla Molnár
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3774
Monitoring the therapeutic response of colorectal cancer (CRC) patients is crucial to determine treatment strategies; therefore, we constructed a liquid biopsy-based approach for tracking tumor dynamics in non-metastatic (nmCRC) and metastatic (mCRC)
Autor:
Sára Zsigrai, Alexandra Kalmár, Barbara K. Barták, Zsófia B. Nagy, Krisztina A. Szigeti, Gábor Valcz, William Kothalawala, Titanilla Dankó, Anna Sebestyén, Gábor Barna, Orsolya Pipek, István Csabai, Zsolt Tulassay, Péter Igaz, István Takács, Béla Molnár
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1820
Folic acid (FA) is a synthetic form of vitamin B9, generally used as a nutritional supplement and an adjunctive medication in cancer therapy. FA is involved in genetic and epigenetic regulation; therefore, it has a dual modulatory role in established