Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Sándor, Paku"'
Autor:
Beáta Szeitz, Zsolt Megyesfalvi, Nicole Woldmar, Zsuzsanna Valkó, Anna Schwendenwein, Nándor Bárány, Sándor Paku, Viktória László, Helga Kiss, Edina Bugyik, Christian Lang, Attila Marcell Szász, Luciana Pizzatti, Krisztina Bogos, Mir Alireza Hoda, Konrad Hoetzenecker, György Marko‐Varga, Peter Horvatovich, Balázs Döme, Karin Schelch, Melinda Rezeli
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background Small‐cell lung cancer (SCLC) molecular subtypes have been primarily characterized based on the expression pattern of the following key transcription regulators: ASCL1 (SCLC‐A), NEUROD1 (SCLC‐N), POU2F3 (SCLC‐P) and YAP1 (
Externí odkaz:
https://doaj.org/article/817dbbeab6fd44cfb710da099fa8d926
Autor:
Judit Berta, Szilvia Török, Júlia Tárnoki-Zách, Orsolya Drozdovszky, József Tóvári, Sándor Paku, Ildikó Kovács, András Czirók, Bernard Masri, Zsolt Megyesfalvi, Henriett Oskolás, Johan Malm, Christian Ingvar, György Markó-Varga, Balázs Döme, Viktória László
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Apelin, a ligand of the APJ receptor, is overexpressed in several human cancers and plays an important role in tumor angiogenesis and growth in various experimental systems. We investigated the role of apelin signaling in the malignant behav
Externí odkaz:
https://doaj.org/article/6db1b99335754b2f8199806375af0954
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Several studies have shown that liver fibrosis, and even cirrhosis can be reversed, disproving the old “dogma” that cirrhosis is irreversible. In addition to scaring, vascular alterations appear to be critically important in the progression of ch
Externí odkaz:
https://doaj.org/article/fc3e8dae80874c43b2be57f1354b8d57
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233736 (2020)
INTRODUCTION:The liver is well known for its enormous regenerative capacity. If the hepatocytes are compromised the reserve stem cells can regrow the lost tissue by means of oval cells differentiating into hepatocytes. We were curious whether this st
Externí odkaz:
https://doaj.org/article/86289a863c8348e5a82e6ea157aa2e7a
Autor:
Edina Bugyik, Vanessza Szabó, Katalin Dezső, András Rókusz, Armanda Szücs, Péter Nagy, József Tóvári, Viktória László, Balázs Döme, Sándor Paku
Publikováno v:
Cancer Communications, Vol 38, Iss 1, Pp 1-11 (2018)
Abstract Background It remains unclear if the vascular and connective tissue structures of primary and metastatic tumors are intrinsically determined or whether these characteristics are defined by the host tissue. Therefore we examined the microanat
Externí odkaz:
https://doaj.org/article/40d0e446d6b44058afa8052ea057a467
Autor:
Júlia Tárnoki-Zách, Elod Mehes, Zsófia Varga-Medveczky, Dona Greta Isai, Nandor Barany, Edina Bugyik, Zsolt Revesz, Sándor Paku, Franciska Erdo, Andras Czirok
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 910 (2021)
There is an increasing demand for transdermal transport measurements to optimize topical drug formulations and to achieve proper penetration profile of cosmetic ingredients. Reflecting ethical concerns the use of both human and animal tissues is beco
Externí odkaz:
https://doaj.org/article/2b87c923bc8d49c8b74449f7fb400ee3
Autor:
Zoltán Hujber, Gábor Petővári, Norbert Szoboszlai, Titanilla Dankó, Noémi Nagy, Csilla Kriston, Ildikó Krencz, Sándor Paku, Olivér Ozohanics, László Drahos, András Jeney, Anna Sebestyén
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)
Abstract Background Multiple studies concluded that oncometabolites (e.g. D-2-hydroxyglutarate (2-HG) related to mutant isocitrate dehydrogenase 1/2 (IDH1/2) and lactate) have tumour promoting potential. Regulatory mechanisms implicated in the mainte
Externí odkaz:
https://doaj.org/article/1c8ed741a22d4def9eb36e58f86bf587
Autor:
Karin Schelch, Anna Tisza, Mir Alireza Hoda, Balazs Dome, Anna Schwendenwein, Balazs Hegedus, Anita Rozsas, Konrad Hoetzenecker, Kristiina Boettiger, Ferenc Rényi-Vámos, Viktoria Laszlo, Sándor Paku, Nandor Barany, Zsolt Megyesfalvi, Christian Lang, Michael Grusch
Publikováno v:
Lung Cancer. 161:128-135
Objectives: Circulating levels of activin A (ActA) and follistatin (FST) have been investigated in various disorders including malignancies. However, to date, their diagnostic and prognostic relevance is largely unknown in small cell lung cancer (SCL
Autor:
Péter Hollósi, Lóránd Váncza, Katalin Karászi, Katalin Dobos, Bálint Péterfia, Enikő Tátrai, Péter Tátrai, Tibor Szarvas, Sándor Paku, László Szilák, Ilona Kovalszky
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1356 (2020)
Syndecan-1 is a transmembrane heparan sulfate proteoglycan which is indispensable in the structural and functional integrity of epithelia. Normal hepatocytes display strong cell surface expression of syndecan-1; however, upon malignant transformation
Externí odkaz:
https://doaj.org/article/1ff1e411c6d34a5399e32d66a6bcc316
Autor:
András Rókusz, Dániel Veres, Armanda Szücs, Edina Bugyik, Miklós Mózes, Sándor Paku, Péter Nagy, Katalin Dezső
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176518 (2017)
BACKGROUND AND AIMS:Ductular reaction is a standard component of fibrotic liver tissue but its function is largely unknown. It is supposed to interact with the matrix producing myofibroblasts and compensate the declining regenerative capacity of hepa
Externí odkaz:
https://doaj.org/article/ab3856e0a54f4fc98e0dfb24636621d7