mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer.

Autor: Casadevall D; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain.; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain., Hernández-Prat A; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., García-Alonso S; Experimental Oncology Group, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Arpí-Llucià O; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Menéndez S; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Qin M; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Guardia C; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Morancho B; Preclinical & Translational Research Program, Vall d'Hebron Institute of Oncology (VHIO)-CIBERONC, Barcelona, Spain., Sánchez-Martín FJ; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Zazo S; Pathology Department, IIS-Hospital Universitario Fundación Jiménez Díaz-CIBERONC, Madrid, Spain., Gavilán E; Department of Experimental Oncology, Instituto Europeo di Oncologia (IEO). Milan, Italy., Sabbaghi MA; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Eroles P; INCLIVA Biomedical Research Institute, Hospital Clínico de Valencia, Universitat de València-CIBERONC, Valencia, Spain., Cejalvo JM; INCLIVA Biomedical Research Institute, Hospital Clínico de Valencia, Universitat de València-CIBERONC, Valencia, Spain., Lluch A; INCLIVA Biomedical Research Institute, Hospital Clínico de Valencia, Universitat de València-CIBERONC, Valencia, Spain., Rojo F; Pathology Department, IIS-Hospital Universitario Fundación Jiménez Díaz-CIBERONC, Madrid, Spain., Pandiella A; Centro de Investigación del Cáncer, CSIC-IBSAL and CIBERONC, Salamanca, Spain., Rovira A; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain.; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain., Albanell J; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain.; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2022 Jul 06; Vol. 20 (7), pp. 1108-1121.

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.

Autor: Montagut C; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain.; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Argilés G; Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.; Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain., Ciardiello F; Seconda Università degli Studi di Napoli, Naples, Italy., Poulsen TT; Symphogen A/S, Ballerup, Denmark., Dienstmann R; Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.; Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain., Kragh M; Symphogen A/S, Ballerup, Denmark., Kopetz S; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston., Lindsted T; Symphogen A/S, Ballerup, Denmark., Ding C; Symphogen A/S, Ballerup, Denmark., Vidal J; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain., Clausell-Tormos J; Symphogen A/S, Ballerup, Denmark., Siravegna G; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Torino, Italy.; FIRC Institute of Molecular Oncology (IFOM), Milan, Italy., Sánchez-Martín FJ; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Koefoed K; Symphogen A/S, Ballerup, Denmark., Pedersen MW; Symphogen A/S, Ballerup, Denmark., Grandal MM; Symphogen A/S, Ballerup, Denmark., Dvorkin M; BHI of Omsk Region 'Clinical Oncology Dispensary,' Omsk, Russia., Wyrwicz L; Centrum Onkologii-Instytut im. M. Sklodowskiej Curie, Warsaw, Poland., Rovira A; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain., Cubillo A; Centro Integral Oncologico Clara Campa, Madrid, Spain., Salazar R; Institut Català d'Oncologia, Institut d'Investigació biomèdica de Bellvitge, CIBERONC, Barcelona, Spain., Desseigne F; Consultation d'Oncologie Génétique, Centre de Lutte Contre le Cancer Leon Berard, Lyon, France., Nadal C; Hospital Clinic of Barcelona, University of Barcelona, Spain., Albanell J; Medical Oncology Department, Hospital del Mar-CIBERONC, Barcelona, Spain.; Cancer Research Program, IMIM (Hospital del Mar Research Institute), Barcelona, Spain.; Pompeu Fabra University, Barcelona, Spain., Zagonel V; Medical Oncology Unit 1, Istituto Oncologico Veneto, IRCCS, Padova, Italy., Siena S; Grande Ospedale Metropolitano Niguarda and Università degli Studi di Milano, Milano, Italy., Fumi G; Azienda Ospedaliera S. Maria Di Terni, Terni, Italy., Rospo G; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Torino, Italy., Nadler P; Symphogen A/S, Ballerup, Denmark., Horak ID; Symphogen A/S, Ballerup, Denmark., Bardelli A; Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Torino, Italy.; University of Torino, School of Medicine, Torino, Italy., Tabernero J; Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.; Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.

Publikováno v: JAMA oncology [JAMA Oncol] 2018 Apr 12; Vol. 4 (4), pp. e175245. Date of Electronic Publication: 2018 Apr 12.

AhR-dependent 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in human neuronal cell line SHSY5Y.

Autor: Morales-Hernández A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain., Corrales-Redondo M; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain., Marcos-Merino JM; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain., González-Rico FJ; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain., Sánchez-Martín FJ; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain., Merino JM; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Extremadura, 06071-Badajoz, Spain. Electronic address: jmmerino@unex.es.

Publikováno v: Neurotoxicology [Neurotoxicology] 2016 Sep; Vol. 56, pp. 55-63. Date of Electronic Publication: 2016 Jul 05.

Prenatal and early postnatal lead exposure in mice: neuroimaging findings.

Autor: Lindquist DM; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA., Beckwith T; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA., Cecil KM; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA., Sánchez-Martín FJ; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA., Landero-Figueroa J; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA., Puga A; 1 Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA ; 2 Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA ; 3 Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, USA.

Publikováno v: Quantitative imaging in medicine and surgery [Quant Imaging Med Surg] 2015 Aug; Vol. 5 (4), pp. 511-8.

Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead.

Autor: Sánchez-Martín FJ; Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Lindquist DM; Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Landero-Figueroa J; Metallomics Center of the Americas, Department of Chemistry, University of Cincinnati, Cincinnati, OH 45219, USA., Zhang X; Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Chen J; Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Cecil KM; Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Medvedovic M; Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Puga A; Department of Environmental Health and Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.

Publikováno v: Neurotoxicology [Neurotoxicology] 2015 Jan; Vol. 46, pp. 92-100. Date of Electronic Publication: 2014 Dec 18.