CDK6 is activated by the atypical cyclin I to promote E2F‐mediated gene expression and cancer cell proliferation

Autor: Eva Quandt, Núria Masip, Sara Hernández‐Ortega, Abril Sánchez‐Botet, Laura Gasa, Ainhoa Fernández‐Elorduy, Sara Plutta, Joan Marc Martínez‐Láinez, Samuel Bru, Pau M. Munoz‐Torres, Martin Floor, Jordi Villà‐Freixa, May C. Morris, August Vidal, Alberto Villanueva, Josep Clotet, Mariana P. C. Ribeiro

Publikováno v: Molecular Oncology, Vol 17, Iss 7, Pp 1228-1245 (2023)

Cyclin‐dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by distinctive structural features, but their partner

Externí odkaz: https://doaj.org/article/4d91340f06a24d8eb0bf9f70674462b3

Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway.

Autor: Sánchez-Botet, Abril¹ (AUTHOR), Quandt, Eva¹ (AUTHOR), Masip, Núria¹ (AUTHOR), Escribá, Rubén^2,3 (AUTHOR), Novellasdemunt, Laura⁴ (AUTHOR), Gasa, Laura¹ (AUTHOR), Li, Vivian S. W.⁴ (AUTHOR), Raya, Ángel^2,3,5 (AUTHOR), Clotet, Josep¹ (AUTHOR) jclotet@uic.es, Ribeiro, Mariana P. C.¹ (AUTHOR) mpontecardosoribeiro@uic.es

Publikováno v: Cellular Oncology (2211-3428). Dec2021, Vol. 44 Issue 6, p1273-1286. 14p.

Author response for 'CDK6 is activated by the atypical cyclin I to promote E2F ‐mediated gene expression and cancer cell proliferation'

Autor: null Eva Quandt, null Núria Masip, null Sara Hernández‐Ortega, null Abril Sánchez‐Botet, null Laura Gasa, null Ainhoa Fernández‐Elorduy, null Sara Plutta, null Joan Marc Martínez‐Láinez, null Samuel Bru, null Pau M. Munoz‐Torres, null Martin Floor, null Jordi Villà‐Freixa, null May C. Morris, null August Vidal, null Alberto Villanueva, null Josep Clotet, null Mariana P.C. Ribeiro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081541c2905d50af9b472ff7e0059db7
https://doi.org/10.1002/1878-0261.13438/v2/response1

Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex

Autor: Núria Masip, Gaetano Verde, Rebecca S. Levin, Stephen J. Kron, Abril Sánchez-Botet, Alma L. Burlingame, Donald Wolfgeher, Eva Quandt, Florentine U. Rutaganira, Laura Gasa, Josep Clotet, Kevan M. Shokat, Sara Hernández-Ortega, Javier Jiménez, Mariana P.C. Ribeiro

Publikováno v: Experimental & molecular medicine, vol 51, iss 4
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-17 (2019)
Recercat. Dipósit de la Recerca de Catalunya
instname
Experimental & Molecular Medicine

CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that forms an active complex with cyclin Y (CCNY). Although both proteins have been recently implicated in cancer pathogenesis, it is still uncl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236fe3488f1831f3b6494a71cd53fcdb
https://escholarship.org/uc/item/8wn0z8nk

La ciclina CNTD2: un nuevo inductor del desarrollo tumoral

Autor: Sánchez Botet, Abril

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

El cáncer colorrectal (CRC) es uno de los cánceres más comunes en todo el mundo, con un 8-10% de estos tumores que presentan una mutación BRAF (V600E). Las ciclinas son oncogenes comúnmente desregulados en muchos cánceres, pero el papel de la n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fcf54b0ad2499b57820b2a6d1cb0521e
http://hdl.handle.net/10803/593163