Výsledky vyhledávání - "Sánchez Tejada L"

DNA Methylation of Tumor Suppressor Genes in Pituitary Neuroendocrine Tumors

Autor: García-Martínez A, Sottile J, Sánchez-Tejada L, Fajardo C, Cámara R, Lamas C, Barberá VM, Picó A

Publikováno v: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante

Context: Epigenetic alterations may play a role in the development and behavior of pituitary neuroendocrine tumors (PitNETs). Objective: To evaluate the effect of methylation of tumor suppressor genes (TSGs) on their gene expression and on the behavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::255e9fea2a0584256a54d523dabd048c
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2597

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Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas

Autor: Gallardo, Alberto, Lerma Puertas, Enrique, Escuin i Borràs, Daniel, Tibau Martorell, Ariadna, Muñoz, J., Ojeda, Belén, Barnadas i Molins, Agustí, Adrover, E., Sánchez-Tejada, L., Giner, D., Ortiz-Martínez, F., Peiró, G.., Universitat Autònoma de Barcelona

Publikováno v: BRITISH JOURNAL OF CANCER
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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British Journal of Cancer
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Breast cancer (BC) is one of the most frequent malignancies in women (Jemal et al, 2008). HER2 overexpressing and/or gene amplified tumours represent approximately 25% of all BC, and they are associated with an aggressive phenotype, metastases, resis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cac20c1602893d68a42739d14a6ff32
https://doi.org/10.1038/bjc.2012.85

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Over-expression of vascular endothelial growth factor in pituitary adenomas is associated with extrasellar growth and recurrence

Autor: Sánchez-Ortiga R, Sánchez-Tejada L, Moreno-Perez O, Riesgo P, Niveiro M, Picó Alfonso AM

Publikováno v: Pituitary
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
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Some pituitary adenomas (PA) demonstrate aggressive behavior with local invasion and recurrences. Angiogenesis is regarded as an essential step in the formation of solid tumors. The aim of this study is to find out whether angiogenic factors may have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::87461b74a0fdec660cbead03245f13c4
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8911

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Pituitary tumor transforming gene and insulin-like growth factor 1 receptor expression and immunohistochemical measurement of Ki-67 as potential prognostic markers of pituitary tumors aggressiveness

Autor: Sánchez-Tejada L, Sánchez-Ortiga R, Moreno-Pérez O, Montañana CF, Niveiro M, Tritos NA, Alfonso AM

Publikováno v: Endocrinologia y Nutricion
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

INTRODUCTION AND OBJECTIVE: The ability to predict recurrence of pituitary adenoma (PA) after surgery may be helpful to determine follow-up frequency and the need for adjuvant treatment. The purpose of this study was to assess the prognostic capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::2fe2b9a82635cd0de48b02a9c3ed4102
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8908

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Papel de pituitary tumour-transforming gene (PTTG) en los adenomas hipofisarios

Autor: Sánchez-Ortiga R, Sánchez Tejada L, Peiró Cabrera G, Moreno-Pérez O, Arias Mendoza N, Aranda López FI, Picó Alfonso A

Publikováno v: Endocrinologia y Nutricion
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

The pathogenesis of pituitary tumours is far to be understood. Pituitary transforming tumour gene (PTTG), a gen that induces aneuploidy, genetic instability, cellular proliferation and to stimulate angiogenesis, has been involved in neoplasic transfo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d7d21f5e4f80b088cd3badd4bbae8ad5
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8891

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