Zobrazeno 1 - 10 of 30 pro vyhledávání: '"Sébastien Anguille"'
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The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells
Autor: Sébastien Anguille, Herman Goossens, Johan M.J. Van den Bergh, Tessa Kerre, Zwi N. Berneman, Marc Peeters, Evelien Smits, Carlo Heirman, Viggo Van Tendeloo, Sarah Bonte, Kris Thielemans, Barbara Stein, Yannick Willemen
Publikováno v: Oncotarget
ONCOTARGET
We formerly demonstrated that vaccination with Wilms tumor 1 (WT1)-loaded autologous monocyte-derived dendritic cells (mo-DCs) can be a well-tolerated effective treatment in acute myeloid leukemia (AML) patients. Here, we investigated whether we coul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c69b80346774f2d5cfcab087a31ada
https://doi.org/10.18632/oncotarget.12170
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2
Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells
Autor: Yannick Willemen, Zwi N. Berneman, Eva Lion, Heleen H. Van Acker, Johan M.J. Van den Bergh, Viggo Van Tendeloo, Evelien Smits, Sébastien Anguille
Publikováno v: Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-13 (2016)
Journal of Hematology & Oncology
Journal of hematology and oncology
Background Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural killer cells and αβ T cells. The advent of γδ T cells is largely due to t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5870a6b9e58b013260bc7e7dc7fbfae
http://link.springer.com/article/10.1186/s13045-016-0329-3
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3
Engineering monocyte-derived dendritic cells to secrete interferon-alpha enhances their ability to promote adaptive and innate anti-tumor immune effector functions
Autor: Viggo Van Tendeloo, Heleen H. Van Acker, Carl G. Figdor, Johan M.J. Van den Bergh, Barbara Stein, Eva Lion, Marc Peeters, Steven Heynderickx, Zwi N. Berneman, Sébastien Anguille, Vicky A. E. Roelandts, I. Jolanda M. de Vries, Gosse J. Adema, Evelien Smits, Yannick Willemen
Publikováno v: Cancer immunology and immunotherapy
Cancer Immunology Immunotherapy, 64, 831-42
Cancer Immunology Immunotherapy, 64, 7, pp. 831-42
Contains fulltext : 155181.pdf (Publisher’s version ) (Open Access) Dendritic cell (DC) vaccination has demonstrated potential in clinical trials as a new effective cancer treatment, but objective and durable clinical responses are confined to a mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8321e0578be2aea15a2594c7a908f4
https://hdl.handle.net/2066/155181
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6
Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy
Autor: Yannick Willemen, Evelien Smits, Johan M.J. Van den Bergh, Eva Lion, Viggo Van Tendeloo, Zwi N. Berneman, Sébastien Anguille, Heleen H. Van Acker
Publikováno v: Human vaccines & immunotherapeutics
Owing to their professional antigen-presenting capacity and unique potential to induce tumor antigen-specific T cell immunity, dendritic cells (DCs) have attracted much interest over the past decades for therapeutic vaccination against cancer. Clinic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6017eae4fb6f045f9cd64262d6fe86d6
https://doi.org/10.4161/hv.25373
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7
Medical costs of treatment and survival of patients with acute myeloid leukemia in Belgium
Autor: Herman Goossens, Wilfried Schroyens, S. Dom, Philippe Beutels, Zwi N. Berneman, Anke Verlinden, I. Cornille, Evelien Smits, Griet Nijs, Viggo Van Tendeloo, A. Gadisseur, Sébastien Anguille, A. Van de Velde
Publikováno v: Leukemia research
The advent of new cell-based immunotherapies for leukemia offers treatment possibilities for certain leukemia subgroups. The wider acceptability of these new technologies in clinical practice will depend on its impact on survival and costs. Due to th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e007954dcdcb5a2c67bfd9479b2ba
https://hdl.handle.net/10067/1335470151162165141
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8
Generation and Cryopreservation of Clinical Grade Wilms’ Tumor 1 mRNA-Loaded Dendritic Cell Vaccines for Cancer Immunotherapy
Autor: Zwi N. Berneman, Yannick Willemen, Griet Nijs, Barbara Stein, Eva Lion, Evelien Smits, Viggo Van Tendeloo, Sébastien Anguille
Publikováno v: Methods in Molecular Biology ISBN: 9781493933365
First described in the 1970s, dendritic cells (DC) are currently subjects of intense investigation to exploit their unique antigen-presenting and immunoregulatory capacities. In cancer, DC show promise to elicit or amplify immune responses directed a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d9289736465b49ca8e1c9b04cb047b4
https://doi.org/10.1007/978-1-4939-3338-9_3
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9
Interferon-α in acute myeloid leukemia: an old drug revisited
Autor: Viggo Van Tendeloo, Sébastien Anguille, Evelien Smits, Zwi N. Berneman, Yannick Willemen, Eva Lion
Publikováno v: Leukemia
Interferon-α (IFN-α), a type I IFN, is a well-known antitumoral agent. The investigation of its clinical properties in acute myeloid leukemia (AML) has been prompted by its pleiotropic antiproliferative and immune effects. So far, integration of IF
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f679b47508e74be359ece5326a4911c
https://doi.org/10.1038/leu.2010.324
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10
Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials
Autor: Heleen H. Van Acker, Evelien Smits, Yannick Willemen, Sébastien Anguille, Viggo Van Tendeloo
Publikováno v: Pharmacology and therapeutics
A growing body of evidence points toward an important anti-cancer effect of bisphosphonates, a group of inexpensive, safe, potent, and long-term stable pharmacologicals that are widely used as osteoporosis drugs. To date, they are already used in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31667bcc93ea7e119a5973b4b5c9e65
https://pubmed.ncbi.nlm.nih.gov/26617219
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