Zobrazeno 1 - 10
of 443
pro vyhledávání: '"S, Zoghbi"'
Autor:
Sridhar Goud Nerella, Sanjay Telu, Jeih-San Liow, Madeline D. Jenkins, Sami S. Zoghbi, Juan L. Gomez, Michael Michaelides, Mark A. G. Eldridge, Barry J. Richmond, Robert B. Innis, Victor W. Pike
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Chemogenetic tools are designed to control neuronal signaling. These tools have the potential to contribute to the understanding of neuropsychiatric disorders and to the development of new treatments. One such chemogenetic technology compris
Externí odkaz:
https://doaj.org/article/dc85f38a8fc449c2a2f81a76b0068687
Autor:
Lisheng Cai, Jeih-San Liow, Cheryl L. Morse, Sanjay Telu, Riley Davies, Lester S. Manly, Sami S. Zoghbi, Frederick T. Chin, Robert B. Innis, Victor W. Pike
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Key points Question: Do GluN2B radioligands 11C-NR2B-Me enantiomers show cross-binding with σ1 receptors in brain in vivo? Pertinent findings: 11C-(+)-NR2B-Me, 11C-(−)-NR2B-Me, 11C-(S)-NR2B-SMe, and 11C-(R)-NR2B-SMe give specific signals in whole
Externí odkaz:
https://doaj.org/article/0a8dea1580224d03a86adc98e17465ab
Autor:
Jae-Hoon Lee, Mattia Veronese, Jeih-San Liow, Cheryl L. Morse, Jose A. Montero Santamaria, Mohammad B. Haskali, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis, Paolo Zanotti-Fregonara
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Background Previous studies found that the positron emission tomography (PET) radioligand [18F]LSN3316612 accurately quantified O-GlcNAcase in human brain using a two-tissue compartment model (2TCM). This study sought to assess kinetic model
Externí odkaz:
https://doaj.org/article/52d77ecbd92a4d8aaad302f00ded1beb
Autor:
Stal Shrestha, Min-Jeong Kim, Mark Eldridge, Michael L. Lehmann, Michael Frankland, Jeih-San Liow, Zu-Xi Yu, Michelle Cortes-Salva, Sanjay Telu, Ioline D. Henter, Evan Gallagher, Jae-Hoon Lee, J. Megan Fredericks, Chelsie Poffenberger, George Tye, Yanira Ruiz-Perdomo, Fernanda Juarez Anaya, Jose A. Montero Santamaria, Robert L. Gladding, Sami S. Zoghbi, Masahiro Fujita, James D. Katz, Victor W. Pike, Robert B. Innis
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background Cyclooxygenase-2 (COX-2), which is rapidly upregulated by inflammation, is a key enzyme catalyzing the rate-limiting step in the synthesis of several inflammatory prostanoids. Successful positron emission tomography (PET) radiolig
Externí odkaz:
https://doaj.org/article/549fdcb2b5f34261b797487884d7bade
Autor:
Jae-Hoon Lee, Jeih-San Liow, Soumen Paul, Cheryl L. Morse, Mohammad B. Haskali, Lester Manly, Sergey Shcherbinin, J. Craig Ruble, Nancy Kant, Emily C. Collins, Hugh N. Nuthall, Paolo Zanotti-Fregonara, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Background Previous studies found that [18F]LSN3316612 was a promising positron emission tomography (PET) radioligand for imaging O-GlcNAcase in nonhuman primates and human volunteers. This study sought to further evaluate the suitability of
Externí odkaz:
https://doaj.org/article/bb5eb72643d84f0aadd17788a06265b4
Autor:
Min-Jeong Kim, Meghan McGwier, Kimberly J. Jenko, Joseph Snow, Cheryl Morse, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis, William C. Kreisl
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1327-1331 (2019)
Abstract This study used 11C‐PBR28 positron emission tomography (PET) imaging to determine whether levels of 18‐kDa translocator protein (TSPO), an inflammation‐specific biomarker, are increased in frontotemporal lobar degeneration (FTLD) patie
Externí odkaz:
https://doaj.org/article/4eb0047842b247e58d7ae1375df09343
Autor:
Stefano Altomonte, Xuefeng Yan, Cheryl L. Morse, Jeih-San Liow, Madeline D. Jenkins, Jose A. Montero Santamaria, Sami S. Zoghbi, Robert B. Innis, Victor W. Pike
Publikováno v:
ACS Pharmacology & Translational Science. 6:614-632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf3e576354872f2e2c39aa3833fb579
https://doi.org/10.1021/acsptsci.3c00003
https://doi.org/10.1021/acsptsci.3c00003
Autor:
Masahiro Fujita, Masato Kobayashi, Masamichi Ikawa, Roger N. Gunn, Eugenii A. Rabiner, David R. Owen, Sami S. Zoghbi, Mohamad B. Haskali, Sanjay Telu, Victor W. Pike, Robert B. Innis
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-5 (2017)
Abstract Translocator protein (TSPO) is a biomarker for detecting neuroinflammation by PET. 11C-(R)-PK11195 has been used to image TSPO since the 1980s. Here, we compared the utility of four 11C-labeled ligands—(R)-PK11195, PBR28, DPA-713, and ER17
Externí odkaz:
https://doaj.org/article/247da3f25f554cfd98e5c523d7c2a91e
Autor:
Min-Jeong Kim, Fernanda Juarez Anaya, Lester S. Manly, Jae-Hoon Lee, Jinsoo Hong, Stal Shrestha, Sanjay Telu, Katharine Henry, Jose A. Montero Santamaria, Jeih-San Liow, Paolo Zanotti-Fregonara, H. Umesha Shetty, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis
Publikováno v:
Journal of Nuclear Medicine. 64:159-164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed86780304dac397af9d1c23e72ea61
https://doi.org/10.2967/jnumed.122.264061
https://doi.org/10.2967/jnumed.122.264061
Autor:
Yuichi Wakabayashi, Per Stenkrona, Ryosuke Arakawa, Xuefeng Yan, Maia G. Van Buskirk, Madeline D. Jenkins, Jose A. Montero Santamaria, Kevin P. Maresca, Akihiro Takano, Jeih-San Liow, Thomas A. Chappie, Andrea Varrone, Sangram Nag, Lei Zhang, Zoë A. Hughes, Christopher J. Schmidt, Shawn D. Doran, Andrew Mannes, Paolo Zanotti-Fregonara, Maarten Ooms, Cheryl L. Morse, Sami S. Zoghbi, Christer Halldin, Victor W. Pike, Robert B. Innis
Publikováno v:
Journal of Nuclear Medicine. 63:1919-1924
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61c7d547cbcb5109418140c2b1e19428
https://doi.org/10.2967/jnumed.122.263838
https://doi.org/10.2967/jnumed.122.263838